@themorrislab.bsky.social
+ Follow
86
followers
110
following
4
posts
Posts
Media
Videos
Starter Packs
themorrislab.bsky.social
@themorrislab.bsky.social
· Apr 30
Looking forward to support the UK’s fundamental biomedical research with the MRC
www.birmingham.ac.uk/news/2025/pr...
Professor Jo Morris to Chair Medical Research Council's Molecular and Cellular Medicine Board - University of Birmingham
The MRC has announced that Birmingham’s Professor Jo Morris will become the new Chair of the MRC Molecular and Cellular Medicine Board (MCMB).
www.birmingham.ac.uk
1
1
3
themorrislab.bsky.social
@themorrislab.bsky.social
· Apr 30
Looking forward to support the UK’s fundamental biomedical research with the MRC
www.birmingham.ac.uk/news/2025/pr...
Professor Jo Morris to Chair Medical Research Council's Molecular and Cellular Medicine Board - University of Birmingham
The MRC has announced that Birmingham’s Professor Jo Morris will become the new Chair of the MRC Molecular and Cellular Medicine Board (MCMB).
www.birmingham.ac.uk
Reposted
Garvin SUMO Biology Lab
@garvinlab.bsky.social
· Apr 23
Nice to see this one out in
@natcomms.nature.com
from
@themorrislab.bsky.social
,
@leneyms.bsky.social
,
@anoopsinghchauhan.bsky.social
,
@profstewartlab.bsky.social
. Still, plenty of surprises into how RNF168 works!
rdcu.be/eiXxy
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance
Nature Communications - The ubiquitin ligase, RNF168, promotes DNA break repair but must be regulated to prevent run-away ubiquitin signaling. Here, the authors identify a three-step...
rdcu.be
1
1
themorrislab.bsky.social
@themorrislab.bsky.social
· Apr 15
How is RNF168 cleared from sites of DNA damage? It’s complicated;
www.nature.com/articles/s41...
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance - Nature Communications
The ubiquitin ligase, RNF168, promotes DNA break repair but must be regulated to prevent run-away ubiquitin signaling. Here, the authors identify a three-step post-translational cascade regulating RNF...
www.nature.com
2
themorrislab.bsky.social
@themorrislab.bsky.social
· Mar 11
We are delighted to announce our first-ever BlueSky post – and the latest paper from our lab. with the Leney Lab
@leneyms.bsky.social
dlvr.it/TJN3yl
@cp-molcell.bsky.social
@unibirmingham.bsky.social
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Garvin et al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In...
dlvr.it
3
16
37
Reposted
Molecular Cell
@cp-molcell.bsky.social
· Mar 6
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Garvin et al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In the DNA damage response, this activity prevents…
dlvr.it
2
4
