About the 2010s « Psychiatric researchers and scientific leaders became acutely aware of the need to play a scientifically well-grounded long game that avoids the kinds of reductive and overconfident claims that had been made in the past. »

Very insightful as usual from @awaisaftab.bsky.social reviewing Elusive cures.
👇One sentence I wish applied to research in 2025 🇫🇷 where 10s of M€ are still being thrown out in dead-end reductionism in a promise to solve things while following the same path.

New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons
www.biorxiv.org/content/10.1...

A subset of dorsal raphe dopamine neurons is critical for survival-oriented vigilance. https://www.biorxiv.org/content/10.1101/2025.03.31.646345v1

This!... + perhaps the financial illness goes beyond bullshit jobs & tasks, to encompass the for-profit obsession of public institutions and the idea that we must prepare students for the private market.
We are failing ourselves so badly by losing focus of our core missions

As far as I can see, a small group of colleagues psychiatrists/scientists have themselves pushed inflammatory reductionism (fantasy)… not some Instagram guru