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Tim Triche, Jr.🔰

@timtriche.bsky.social

5.4K followers 1.4K following 4.3K posts

Resident panhandler, http://trichelab.org/ Posts may contain trace quantities of blood🩸, chromatin 🧬, and stats 🧮 CV: https://scholar.google.com/citations?user=AOoIO74AAAAJ Views expressed are my own (but for the right price they can be yours!)

trichelab.org

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Tim Triche, Jr.🔰 @timtriche.bsky.social · Jan 23

NIH funded research benefits your community even if it doesn’t (yet!) directly benefit you. Each $ invested in NIH yields significantly higher return on investment (average 254%) than the same $ invested in “defense”.

Call your reps: (202) 224-3121

www.unitedformedicalresearch.org/nih-in-your-...

Non-defense spending such as NIH yields SIGNIFICANTLY higher return on investment than defense spending.

In Michigan alone, $991M of NIH funding creates $2420M of economic activity, a 244% return on investment.

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 15h

Small language models are becoming more fashionable

Tim Triche, Jr.🔰 @timtriche.bsky.social · 15h

That’s cool but can you run the model on an RPN calculator? Gotta throw down 😉

Tim Triche, Jr.🔰 @timtriche.bsky.social · 15h

Good news for these guys: the United States is not such a country

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 15h

Sunglasses and a hat are great. There’s also a reason I, a fair skinned individual, usually keep at least a remedial beard around. (Unlike sunscreen, it does not wear off.)

A lifetime in the mountains has torched my forearms, though. That’s the part of me that really looks 50.

Tim Triche, Jr.🔰 @timtriche.bsky.social · 16h

Do take care of your back
Do take care of your knees

Don’t get too fat (see above)
Don’t get too lazy (above)

Go new places, meet people

Do something enjoyable enough that, if it doesn’t work out, you haven’t thrown away your youth for someone else’s benefit

Work really hard and one day this can be you:

(On a tombstone)

RIP
Worked Really Hard

Tim Triche, Jr.🔰 @timtriche.bsky.social · 16h

I strongly doubt that Rubio is ignorant. You don’t get to be a senator by being an ignorant fool (unless you win a lot of sportsball trophies in the SEC, and little Marco did not do that)

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 16h

Staring into the abyss for 8 hours a day makes for great bar stories and severe mental health issues later

I swear, we knew this 30 years ago, why is anyone pretending it isn’t so?

This is exactly what “AI” is for: attempting binary classification (with occasional human review) of OK / not OK

Tim Triche, Jr.🔰 @timtriche.bsky.social · 16h

Very well, every institute of higher learning shall have an MLK boulevard

(The “ of his time “ is understood, you see)

Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

Excellent first sentence of the introduction, doubly so for these Lysenkoist times.

Neat work!

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

5) cheapdate
6) fruitless (ahem)

Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

Feynman had trouble following McClintock’s work. But then, plenty of biology grad students have trouble following Luria & Delbruck. Science is tough

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

Sounds about right

Hiring MBAs to run the joint might not have been the best idea

Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

This is why I send propublica $5/month.

Comforting the afflicted and afflicting the comfortable ✊

Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

This is a Hadley-ism. He’s jealous because he was not named Hadley Rickham

Tim Triche, Jr.🔰 @timtriche.bsky.social · 1d

Very possibly the best use of this meme format, full stop. Medical geneticists do not care about all those alts and haplotypes used to misplace HLA types and MHC reads. Medical geneticists do care that the reads aren’t in a sensible place on chr6

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

Failure to take any responsibility for their bully pulpit, more like it

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

Yeah it sucks to bite the bullet but it is 1000x worse to let it fester, and it is wrong to air dirty laundry in public (or semi-public) unless and until the alternatives have demonstrably failed.

If this job was easy nobody would pay us to do it, and these are the hardest parts imho

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

🤞

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

not wrong -- maybe if humans had more respect for the world around us, we might have more respect for each other. maybe.

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

Emmanuel Candes' JSM 2012 and JSM 2017 talks are all anyone really needs tbh

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

hmm, I vaguely remember something about the Hutus in Rwanda referring to Tutsis as "cockroaches" prior to the genocide. Of course the difference is that in other countries, there are consequences for such behavior: foreignpolicy.com/2016/04/15/r...

Rwandan Who Called Tutsis ‘Cockroaches’ in 1992 Gets Life Sentence

A man accused of encouraging the genocide in Rwanda has been sentenced to life in prison.

foreignpolicy.com

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

nb. tensors or stacks of matrices represented as fiber bundles fall into this category obviously. in the end everything that has a convergence bound and an eventually-computable gradient is "just statistics"

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

the number of linear decompositions, low-rank-and-sparse representations, tied autoencoders, etc. that we have benchmarked based on reconstruction error and compression is absurd. At the end of the day most people just want an SVD without sign flips and with a decent rank selection metric.

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

Who? All I hear about is ballrooms and fat generals

Tim Triche, Jr.🔰 @timtriche.bsky.social · 2d

Bart is on here: @bartdeplancke.bsky.social