Tony Kelly
@tonykellyeu.bsky.social
46 followers 87 following 12 posts
Bringing deep neuroscience and epilepsy domain expertise to data science
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tonykellyeu.bsky.social
Recently I referred to how dendritic compartmentalisation increases computation.
What is a computational unit. How has the view evolved from point neuron (basis for ANNs). How a neuroscience view may increase AI efficiency.
buff.ly/zoF1rJz
preprint on compartmentalisation buff.ly/TAsJuVr
biological neuron is not same as point neuron
tonykellyeu.bsky.social
It was great working with @JuanEdoRG @NetanelOfer @mbarboni92 @TTchumatchenko @ValentinNagerl @HeinzBeck8 and all the other contributors
at @UniklinikBonn @UniBonn @DZNE
tonykellyeu.bsky.social
Dendrites have been under the microscope, since 1888. We took it further and put dendrites under 3 different microscopes (ExM, STED, EM) and reconstructed entire branches to reveal fine nanoscale details. #SuperResolution #ElectronMicroscopy #Morphology
https://doi.org/10.1101/2025.07.18.664460
tonykellyeu.bsky.social
Pleasure working with @Maikl_Wenzel & @NicolaMasala1, as well as @ptrrupprecht, @Norambr, @FritjofHelmchen, @yusterafa, @HeinzBeck8, Xless Martin Fuhrmann, Manuel Mittag, Darik A. O’Neil, Fabian Distler.
Across different institutions @UniBonn, @DZNE_en @Columbia_NTC, @UZH_en 3/3
tonykellyeu.bsky.social
Very happy our cautionary tale of GECI expression in the hippocampus is out in @eLife.
https://elifesciences.org/articles/93804
We describe Ca2+ waves though the hippocampus. Mesmerising but artefact of GECI expression.
Also a tweet print https://x.com/tonykellyEU/status/1723654794626154891. 1/3
tonykellyeu.bsky.social
Our @eLife paper on artefactual Ca2+ waves following calcium indicator expression is highlighted in neuroscience magazine @_TheTransmitter. Really nice talking with @avaskham and seeing the perspectives from @Sheffield_Lab, @DanielDombeck & @LoogerL https://t.co/vqy9K5hEeP
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
www.thetransmitter.org
tonykellyeu.bsky.social
Nice work on how differences in dendritic morphology btwn human and mouse neurons impact dendritic excitability. https://x.com/GregStuartLab/status/1602900777328332800
tonykellyeu.bsky.social
Thanks also to @Brain1878 and reviewers. One of my most positive review processes, working how it should:
The referees had critical points
We responded with changes and experiments.
Always their intent was to improve the ms.
Thanks to the referees it is a much stronger paper
tonykellyeu.bsky.social
appreciate all the work from everyone who contributed to make this a great paper. It has been a massive effort from everyone. @heinzbeck, @marpofahl, @haubrich_andre @MaryPasn, @KirstenBohmbach
@HennebergerLab, @LalaEwell and the twitterless others...