Translucence Biosystems
@translucencebio.bsky.social
Leaders in next-generation 3D histology and AI-powered quantification for intact biological samples
Day 3 of #Neuroscience2025! Join us for our final poster highlighting collaborative work with Innopsys on “High Throughput Immunohistochemistry Imaging and Quantification Using PMT-Generated Images and Cloud-Based ML-Powered Software” (PSTR198.22) from 8 AM - 12 PM.
November 17, 2025 at 4:42 PM
Day 3 of #Neuroscience2025! Join us for our final poster highlighting collaborative work with Innopsys on “High Throughput Immunohistochemistry Imaging and Quantification Using PMT-Generated Images and Cloud-Based ML-Powered Software” (PSTR198.22) from 8 AM - 12 PM.
We're presenting three posters today from 1-5 PM covering brain-wide quantification of AD pathology (PSTR111.19), tools for mapping neuronal activity with Npas4 and cFos (PSTR143.04), and brain-wide quantification of antibody therapeutics (PSTR111.18), highlighting our collaborative work with Roche.
November 16, 2025 at 7:51 PM
We're presenting three posters today from 1-5 PM covering brain-wide quantification of AD pathology (PSTR111.19), tools for mapping neuronal activity with Npas4 and cFos (PSTR143.04), and brain-wide quantification of antibody therapeutics (PSTR111.18), highlighting our collaborative work with Roche.
Booths open today! Find us at Booth #3224 during #SfN25 from Nov. 15-19, where we'll be sharing our latest advances in tissue clearing, light sheet imaging, and 3D quantification. We're also presenting posters throughout the conference. Stay tuned for poster presentation details!
November 16, 2025 at 7:00 AM
Booths open today! Find us at Booth #3224 during #SfN25 from Nov. 15-19, where we'll be sharing our latest advances in tissue clearing, light sheet imaging, and 3D quantification. We're also presenting posters throughout the conference. Stay tuned for poster presentation details!
Today we will be presenting our first poster (PSTR049.03), where we will highlight tools we've developed to streamline the analysis of large, terabyte-scale light sheet datasets.
November 15, 2025 at 11:09 PM
Today we will be presenting our first poster (PSTR049.03), where we will highlight tools we've developed to streamline the analysis of large, terabyte-scale light sheet datasets.
If you have been following along, you will know that we are sharing multiple posters at the Society for Neuroscience (SfN) Annual Meeting in San Diego, California!
November 15, 2025 at 10:54 PM
If you have been following along, you will know that we are sharing multiple posters at the Society for Neuroscience (SfN) Annual Meeting in San Diego, California!
We are excited to announce another poster that we have worked on in collaboration with Innopsys.
November 13, 2025 at 7:51 PM
We are excited to announce another poster that we have worked on in collaboration with Innopsys.
Thank you for joining us at our recent Lunch and Learn, hosted in collaboration with the Innovation Core at the Weill Institute for Neurosciences at the University of California, San Francisco.
November 7, 2025 at 7:29 PM
Thank you for joining us at our recent Lunch and Learn, hosted in collaboration with the Innovation Core at the Weill Institute for Neurosciences at the University of California, San Francisco.
Happening tomorrow! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco.
November 4, 2025 at 10:24 PM
Happening tomorrow! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco.
Time is running out! Grab a spot while you still can! Next week, join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco, on Wednesday, November 5th!
October 30, 2025 at 7:45 AM
Time is running out! Grab a spot while you still can! Next week, join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco, on Wednesday, November 5th!
Happening in a few weeks! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco on November 5th!
October 24, 2025 at 11:58 PM
Happening in a few weeks! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco on November 5th!
Recent FDA approvals of antibody therapeutics for Alzheimer's Disease, such as Leqembi and Kinsula, mark an important advancement in CNS drug discovery. (1/5)
October 21, 2025 at 7:31 PM
Recent FDA approvals of antibody therapeutics for Alzheimer's Disease, such as Leqembi and Kinsula, mark an important advancement in CNS drug discovery. (1/5)
Translucence Biosystems will be hosting a Lunch and Learn in collaboration with the Innovation Core at the Weill Institute for Neurosciences at the University of California, San Francisco, on November 5th!
October 14, 2025 at 4:54 PM
Translucence Biosystems will be hosting a Lunch and Learn in collaboration with the Innovation Core at the Weill Institute for Neurosciences at the University of California, San Francisco, on November 5th!
Happy #FluorescenceFriday! This video, generated by Jose Maldonado, shows Myelin Basic Protein (MBP) in a whole-mouse brain.
MBP is a component of the myelin sheath, which insulates nerve fibers and plays an important role in nerve signal transmission. →
MBP is a component of the myelin sheath, which insulates nerve fibers and plays an important role in nerve signal transmission. →
October 10, 2025 at 5:32 PM
Happy #FluorescenceFriday! This video, generated by Jose Maldonado, shows Myelin Basic Protein (MBP) in a whole-mouse brain.
MBP is a component of the myelin sheath, which insulates nerve fibers and plays an important role in nerve signal transmission. →
MBP is a component of the myelin sheath, which insulates nerve fibers and plays an important role in nerve signal transmission. →
We are excited to announce we'll be attending #SfN25 in San Diego, California, from Nov. 15-19. Visit Translucence Biosystems at Booth #3224 to learn about our latest advances in whole-brain imaging and tissue clearing.
October 9, 2025 at 12:37 AM
We are excited to announce we'll be attending #SfN25 in San Diego, California, from Nov. 15-19. Visit Translucence Biosystems at Booth #3224 to learn about our latest advances in whole-brain imaging and tissue clearing.
We are excited to highlight tissue clearing data generated by Dr. Ian Smith at @ucirvine.bsky.social. This cleared mouse brain sample, stained for amyloid (Amylo-Glo, green) and capillaries (cyan), reveals the brain’s microvascular network and amyloid pathology in intact tissue.
September 25, 2025 at 4:45 PM
We are excited to highlight tissue clearing data generated by Dr. Ian Smith at @ucirvine.bsky.social. This cleared mouse brain sample, stained for amyloid (Amylo-Glo, green) and capillaries (cyan), reveals the brain’s microvascular network and amyloid pathology in intact tissue.
We appreciate the kind words from one of our kit users, Dr. Ian Smith! Dr. Smith is a Research Professor at the University of California, Irvine, and used the Translucence Universal Tissue Clearing Kit to clear a mouse brain.
September 5, 2025 at 2:54 AM
We appreciate the kind words from one of our kit users, Dr. Ian Smith! Dr. Smith is a Research Professor at the University of California, Irvine, and used the Translucence Universal Tissue Clearing Kit to clear a mouse brain.
Happy #FluorescenceFriday! This video, generated by Jose Maldonado, of a mouse brain stained for Tyrosine Hydroxylase (TH) reveals dopaminergic neurons using our Universal Tissue Clearing Kit!
August 30, 2025 at 1:04 AM
Happy #FluorescenceFriday! This video, generated by Jose Maldonado, of a mouse brain stained for Tyrosine Hydroxylase (TH) reveals dopaminergic neurons using our Universal Tissue Clearing Kit!
We’re excited to share beautiful data from one of our kit users, UC Irvine Research Professor Dr. Ian F. Smith. Using the Translucence Universal Tissue Clearing Kit, Dr. Smith cleared a mouse brain to visualize amyloid (Amylo-Glo, green) and capillaries (cyan).
August 27, 2025 at 3:14 PM
We’re excited to share beautiful data from one of our kit users, UC Irvine Research Professor Dr. Ian F. Smith. Using the Translucence Universal Tissue Clearing Kit, Dr. Smith cleared a mouse brain to visualize amyloid (Amylo-Glo, green) and capillaries (cyan).
Happy #FluorescenceFriday! iDISCO-based tissue clearing and whole-organ Light Sheet Fluorescence Microscopy (#LSFM) reveal 3D vasculature and bile duct networks in an intact mouse liver stained for Smooth Muscle Actin (cyan; vasculature) and Cytokeratin 7 (green; bile ducts).
August 22, 2025 at 9:43 PM
Happy #FluorescenceFriday! iDISCO-based tissue clearing and whole-organ Light Sheet Fluorescence Microscopy (#LSFM) reveal 3D vasculature and bile duct networks in an intact mouse liver stained for Smooth Muscle Actin (cyan; vasculature) and Cytokeratin 7 (green; bile ducts).
Congratulations to the team at Denali Therapeutics on their new publication in Science showing that a transferrin receptor–targeted antibody vehicle enhances brain delivery of anti-amyloid therapy while reducing ARIA.
August 22, 2025 at 1:30 AM
Congratulations to the team at Denali Therapeutics on their new publication in Science showing that a transferrin receptor–targeted antibody vehicle enhances brain delivery of anti-amyloid therapy while reducing ARIA.
Jenna McCloskey is a Ph.D. candidate in the Neuroscience Graduate Program at @umich.edu and recently used a Translucence Neuronal Activity Tissue Clearing Kit for her rat‑brain work. See what she has to say about the kits below!
August 14, 2025 at 8:07 PM
Jenna McCloskey is a Ph.D. candidate in the Neuroscience Graduate Program at @umich.edu and recently used a Translucence Neuronal Activity Tissue Clearing Kit for her rat‑brain work. See what she has to say about the kits below!
New publication in @nature.com Neuroscience from our collaboration with the Olson Lab (@ucdavis.bsky.social) and the Heifits Lab (Stanford). The study demonstrates that TBG—a non-hallucinogenic analogue of 5-MeO-DMT—can promote cortical neuroplasticity without inducing hallucinogenic effects.
August 14, 2025 at 3:13 AM
New publication in @nature.com Neuroscience from our collaboration with the Olson Lab (@ucdavis.bsky.social) and the Heifits Lab (Stanford). The study demonstrates that TBG—a non-hallucinogenic analogue of 5-MeO-DMT—can promote cortical neuroplasticity without inducing hallucinogenic effects.