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Trials Change Lives @trialschangelives.bsky.social · 9h

#WordsOfToday "Good understanding needs calm and clear speaking, not anger and shouting" Martin Roquebrune, 2023
#BeCalm
#QuotesDaily
#Roquebrune

Trials Change Lives @trialschangelives.bsky.social · 11h

#CochraneDaily Among the Cochrane reviews of motor neurone disease, one from 2023 found a complete lack of randomised trials of methods for informing people with amyotrophic lateral sclerosis/motor neuron disease of their diagnosis
www.cochranelibrary.com/cdsr/doi/10....
#MND #ALS @cochrane.org

Methods for informing people with amyotrophic lateral sclerosis/motor neuron disease of their diagnosis - Bongioanni, P - 2023 | Cochrane Library

Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

www.cochranelibrary.com

Trials Change Lives @trialschangelives.bsky.social · 1d

#WordsOfToday "Simply opening your hand turns a fist for fighting into a palm for greeting” Joe Muredach, 1971
#QuoteForToday #Quotes #Quotation #GreatestQuotes

Trials Change Lives @trialschangelives.bsky.social · 1d

#CochraneDaily Today's comparison of the frequency of words in the Cochrane Library finds 35 Cochrane reviews containing the word "biscuit", 15 containing "cake" and 5 with both
#Biscuit #Cake
#CochraneLibrary #EvidenceSynthesis

Trials Change Lives @trialschangelives.bsky.social · 2d

For this week's reading and learning: when you can find >210,000 records in PubMed with a simple search for "meta-analyses OR meta-analysis", read this article by Kay Dickersin and colleagues about searching for #meta-analyses 35 years ago
www.sciencedirect.com/science/arti...
#EvidenceSynthesis

Identification of meta-analyses: The need for standard terminology

Our efforts to identify published articles describing meta-analyses of clinical trials illustrate the need for standard terminology to facilitate retr…

www.sciencedirect.com

Trials Change Lives @trialschangelives.bsky.social · 2d

#WordsOfToday “Smile. It is probably one of the cheapest things to do that brings most value, both to the receiver and the giver." John Barcroft 2007 www.nationaldaycalendar.com/internationa...
#WorldSmileDay #Smile
#GreatestQuotes

WORLD SMILE DAY | First Friday in October

WORLD SMILE DAY Each year on the first Friday in October, World Smile Day devotes a day to smiles and spreading random acts of kindness. #WorldSmileDay If

www.nationaldaycalendar.com

Trials Change Lives @trialschangelives.bsky.social · 2d

#CochraneDaily On #WorldCerebralPalsy Day (worldcpday.org), read this analysis of risk of bias assessments in 145 systematic reviews of interventions for cerebral palsy www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#CerebralPalsy
#RiskofBias #EvidenceSynthesis

World Cerebral Palsy Day – October 6th

worldcpday.org

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Trials Change Lives @trialschangelives.bsky.social · 6d

#WordsOfToday “The words spoken are important, not the mouth that said them." Kenmeina Kotoba, 1652
#QuoteForToday #GreatestQuotes

Trials Change Lives @trialschangelives.bsky.social · 6d

#CochraneDaily In September 2025 the Cochrane Library published 10 new reviews, 5 updated reviews where the conclusions had changed, 4 other updated reviews and one review that was given a new citation because of the changes needed to correct errors
#CochraneLibrary #EvidenceSynthesis
@cochrane.org

Trials Change Lives @trialschangelives.bsky.social · 7d

#WordsOfToday Here's a #quote for International Coffee Day www.internationalcoffeeday.org "There should always be a good time to stand, stretch and smell the coffee." Puti Edami, 2007
#Coffee #Stretch #InternationalCoffeeDay
#QuotesToLiveBy #PutiEdami

International Coffee Organization | International Coffee Day

International Coffee Day provides an opportunity for coffee enthusiasts to share their love of the beverage and support the millions of farmers whose livelihoods depend on this aromatic crop. This 1...

www.internationalcoffeeday.org

Trials Change Lives @trialschangelives.bsky.social · 7d

#CochraneDaily On #InternationalMusicDay (imc-cim.org/internationa...), there are many Cochrane reviews of #music therapy, including, most recently, the third update of one on music‐based therapies for people with #dementia @cochrane.org

www.cochranelibrary.com/cdsr/doi/10....

International Music Day – International Music Council

Following a resolution adopted at the 15th IMC General Assembly in Lausanne in 1973, the International Music Day was initiated in 1975 by Lord Yehudi Menuhin, President of the organisation from 1969 to 1975.

imc-cim.org

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Trials Change Lives @trialschangelives.bsky.social · 8d

#WordsOfToday "He does his best thinking when he's taking me for a walk" Max (he/him, adolescent, dog)

#QuoteOfToday #GreatestQuotes
#Dog #WalkTheDog

Trials Change Lives @trialschangelives.bsky.social · 8d

Here they are

Trials Change Lives @trialschangelives.bsky.social · 8d

#CochraneDaily Read reflections from Andy Oxman, Iain Chalmers and Paul Glasziou on the long and winding road of promoting informed health choices in this new James Lind Library article👇
www.jameslindlibrary.org/articles/pro...

@jameslindlibrary.bsky.social @cochrane.org @paulglasziou.bsky.social

Promoting informed health choices: the long and winding road. - The James Lind Library

Summary Those promoting evaluation of the effects of health interventions to inform health choices face numerous challenges. The list includes: uncritical reliance on inadequately informed opinions, i...

www.jameslindlibrary.org

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Trials Change Lives @trialschangelives.bsky.social · 9d

#WordsOfToday "If you went around again on the journey of life, what different career or life path would you choose?" Anon, 1989
#GreatestQuotes #QuoteOfTheDay #QuotesDaily

Trials Change Lives @trialschangelives.bsky.social · 9d

#CochraneDaily 28 September was World Rabies Day. #Cochrane review of treatment of mammalian bites highlights importance of preventing infections such as #rabies and #tetanus.
www.who.int/campaigns/wo...
www.cochranelibrary.com/cdsr/doi/10....
#WorldRabiesDay

World Rabies Day

World Rabies Day is celebrated annually to raise awareness about rabies prevention and to highlight progress in defeating this horrifying disease.

www.who.int

Trials Change Lives @trialschangelives.bsky.social · 12d

#WordsOfToday "Would trying to solve the puzzle of designing a study to solve the puzzle of whether people solving puzzles is good for the brain, help solve the puzzle?" Oko Dus, 2020

#Puzzle #Sudoku #Crossword
#RandomizedTrials #RCT
#WhoseTrialIsItAnyway?
#QuotesDaily

Trials Change Lives @trialschangelives.bsky.social · 12d

#CochraneDaily Just published! Study from Iberoamerican Cochrane Centre, Cochrane Ecuador and others found significant gaps in reporting compliance and #riskofbias of randomised trials published in Latin American #nursing journals
pubmed.ncbi.nlm.nih.gov/40993964/
#RoB #RCT #Cochrane
@cochrane.org

Quality and Bias in Randomized Controlled Trials Published in Latin American Nursing Journals: A Meta-Epidemiological Study - PubMed

Reporting compliance and risk of bias of RCTs published in Latin American nursing journals presents significant gaps, particularly in key methodological domains. These shortcomings hinder transparency...

pubmed.ncbi.nlm.nih.gov

Trials Change Lives @trialschangelives.bsky.social · 13d

#WordsOfToday Here's a quote for this National Cooking Day (www.daysoftheyear.com/days/cooking... ): "Maths of cooking: flour + water + heat = bread." Ric Etta, 1981
#QuotesDaily #GreatestQuotes
#Cooking #NationalCookingDay #Masterchef #Maths

National Cooking Day

Nothing beats the flavor and richness of a well-crafted, home-cooked meal. Dig out your recipe book, buy fresh ingredients, and spend some time in the kitchen.

www.daysoftheyear.com

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Trials Change Lives @trialschangelives.bsky.social · 13d

#CochraneDaily Promising results from trial of gene therapy for #Huntington Disease
www.science.org/content/arti...
#Cochrane reviews from 2009 show lack of effective treatments for symptoms or slowing progression
www.cochranelibrary.com/cdsr/doi/10....
www.cochranelibrary.com/cdsr/doi/10....

In a first, a gene therapy seems to slow Huntington disease

Small study suggests uniQure drug could be first successful treatment for devastating brain disorder

www.science.org

Trials Change Lives @trialschangelives.bsky.social · 14d

#WordsOfToday "The longer you delay planting the seeds, the longer you will wait to harvest the crop and eat the food" Hagear Beid, 2020
#ActNow #TimeToAct
#QuotesToLiveBy #GreatestQuotes
#Gardening

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Trials Change Lives @trialschangelives.bsky.social · 14d

5/5 We are long over due it being time to act to answer Doug Altman's call from 31 years ago for "less research, better research, and research done for the right reasons".
www.bmj.com/content/308/...
trialsjournal.biomedcentral.com/articles/10....
@streweek.bsky.social

Trials Change Lives @trialschangelives.bsky.social · 14d

4/5 ... when we still see conclusions such as "There is insufficient evidence to determine whether there is any difference in effectiveness between different methods ...", even in the second update of a #Cochrane review that began in 2008.
www.cochranelibrary.com/cdsr/doi/10....

Synchronised approach for intrauterine insemination in subfertile couples - Adesina, M - 2025 | Cochrane Library

Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

www.cochranelibrary.com

1

Trials Change Lives @trialschangelives.bsky.social · 14d

3/5 The problem might not be with the current evidence syntheses system but with the system producing the research for review, ...

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Trials Change Lives @trialschangelives.bsky.social · 14d

2/5 ... we also need much more emphasis on the need for better research to feed into those evidence syntheses. No matter how important it is to do the evidence synthesis, and no matter how well it is conducted, it cannot provide robust and reliable answers without robust and reliable research.

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