Tulsi Upadhyay
@tulsiupadhyay.bsky.social
Postdoctoral fellow at Bogyo Lab, Stanford University| Protein Biochemist| Proud IISER Bhopal Alumni
Excited to share my First GRS and GRC moments. It was very special #Bioorganic GRC2025. Met my PhD advisor @saraogi-ishu.bsky.social. Great Science and networking. Won “Outstanding Poster” award.
Thanks to my postdoc advisor @mbogyo.bsky.social for the opportunity to present in GRC with him.
Thanks to my postdoc advisor @mbogyo.bsky.social for the opportunity to present in GRC with him.
June 25, 2025 at 8:39 PM
Excited to share my First GRS and GRC moments. It was very special #Bioorganic GRC2025. Met my PhD advisor @saraogi-ishu.bsky.social. Great Science and networking. Won “Outstanding Poster” award.
Thanks to my postdoc advisor @mbogyo.bsky.social for the opportunity to present in GRC with him.
Thanks to my postdoc advisor @mbogyo.bsky.social for the opportunity to present in GRC with him.
I'm thrilled to share that my second paper from my postdoctoral work is now published! A heartfelt thank you to my PI, Prof. Bogyo @mbogyo.bsky.social, for his unwavering support throughout this project. I am also deeply grateful to our fantastic collaboration team for making it a great success.🙌
Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work from @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. #chembio
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Nature Communications
Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. New tools are needed to both image and treat this pathogen. We previously identified a group of S. aureus serine hy...
link.springer.com
May 30, 2025 at 11:26 PM
I'm thrilled to share that my second paper from my postdoctoral work is now published! A heartfelt thank you to my PI, Prof. Bogyo @mbogyo.bsky.social, for his unwavering support throughout this project. I am also deeply grateful to our fantastic collaboration team for making it a great success.🙌
Reposted by Tulsi Upadhyay
🧪 Working to develop #drugs to treat #chikungunya ? Check out new fluorogenic substrates that help read out viral protease activity, developed by @tulsiupadhyay.bsky.social @westberglab.com @eunayoo.bsky.social @michaelzlin.bsky.social et al! pubmed.ncbi.nlm.nih.gov/39981948/
March 3, 2025 at 8:57 PM
🧪 Working to develop #drugs to treat #chikungunya ? Check out new fluorogenic substrates that help read out viral protease activity, developed by @tulsiupadhyay.bsky.social @westberglab.com @eunayoo.bsky.social @michaelzlin.bsky.social et al! pubmed.ncbi.nlm.nih.gov/39981948/
Reposted by Tulsi Upadhyay
Amazing work by @sijiewang.bsky.social and our collaborators is out in JACS today. Interested in covalent inhibitors of protein-protein interactions? Check it out. pubs.acs.org/doi/10.1021/...
Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display
Peptide macrocycles are promising therapeutics for a variety of disease indications due to their overall metabolic stability and potential to make highly selective binding interactions with targets. R...
pubs.acs.org
February 25, 2025 at 2:51 AM
Amazing work by @sijiewang.bsky.social and our collaborators is out in JACS today. Interested in covalent inhibitors of protein-protein interactions? Check it out. pubs.acs.org/doi/10.1021/...
Reposted by Tulsi Upadhyay
New article out in ACS Infectious Diseases! Using activity-based probes by H. Overkleeft, former PhD candidate @jalal228.bsky.social identified an alpha-amylase family protein of S. aureus supporting virulence during Galleria infection! @monaj66.bsky.social pubs.acs.org/doi/10.1021/...
Activity-Based Protein Profiling Identifies an α-Amylase Family Protein Contributing to the Virulence of Methicillin-Resistant Staphylococcus aureus
In search of new putative antimicrobial drug targets in methicillin-resistant Staphylococcus aureus, we aimed to identify and characterize retaining glycosidase activities in this bacterial pathogen. ...
pubs.acs.org
February 11, 2025 at 8:38 AM
New article out in ACS Infectious Diseases! Using activity-based probes by H. Overkleeft, former PhD candidate @jalal228.bsky.social identified an alpha-amylase family protein of S. aureus supporting virulence during Galleria infection! @monaj66.bsky.social pubs.acs.org/doi/10.1021/...
Reposted by Tulsi Upadhyay
Another big publication from @sijiewang.bsky.social this week. Check out our efforts to use mRNA display to screen for covalent binding inhibitors of Staphylococcus aureus serine hydrolases. pubs.acs.org/articlesonre...
pubs.acs.org
February 27, 2025 at 4:54 PM
Another big publication from @sijiewang.bsky.social this week. Check out our efforts to use mRNA display to screen for covalent binding inhibitors of Staphylococcus aureus serine hydrolases. pubs.acs.org/articlesonre...
Reposted by Tulsi Upadhyay
Cool new preprint from @stanford-chemh.bsky.social fellow @mbogyo.bsky.social @stanfordmedicine.bsky.social
www.researchsquare.com/article/rs-5...
www.researchsquare.com/article/rs-5...
Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation
Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. This is largely because infection sites are often difficult to localize and the bacteria forms biofilms which are n...
www.researchsquare.com
January 10, 2025 at 1:03 PM
Cool new preprint from @stanford-chemh.bsky.social fellow @mbogyo.bsky.social @stanfordmedicine.bsky.social
www.researchsquare.com/article/rs-5...
www.researchsquare.com/article/rs-5...
Excited to repost the news on this new platform!! Great collaborative work under the mentorship of @mbogyo.bsky.social is out for your read.
First real post on @bsky.app! Check out our latest work identifying covalent fragments as inhibitors of the Fph serine hydrolases in S. aureus. Great work from Tulsi Upadhyay and our many collaborators. www.researchsquare.com/article/rs-5...
Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation
Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. This is largely because infection sites are often difficult to localize and the bacteria forms biofilms which are n...
www.researchsquare.com
January 10, 2025 at 7:53 PM
Excited to repost the news on this new platform!! Great collaborative work under the mentorship of @mbogyo.bsky.social is out for your read.