Uli Stelzl
@ulistelzl.bsky.social
Ulrich Stelzl, molecular life sciences at University of Graz, Austria
Reposted by Uli Stelzl
The cytosolic PRMT5-CDK4 complex impairs cell cycle kinase signaling https://www.biorxiv.org/content/10.64898/2025.12.11.693714v1
December 14, 2025 at 7:02 PM
The cytosolic PRMT5-CDK4 complex impairs cell cycle kinase signaling https://www.biorxiv.org/content/10.64898/2025.12.11.693714v1
Reposted by Uli Stelzl
8/ Conclusion: This study provides evolutionary and functional insights into germline piRNA production across Drosophila species, highlighting the dynamic nature of protein-protein interactions in genome defence pathways.
October 30, 2024 at 1:59 PM
8/ Conclusion: This study provides evolutionary and functional insights into germline piRNA production across Drosophila species, highlighting the dynamic nature of protein-protein interactions in genome defence pathways.
Reposted by Uli Stelzl
🧬 New PAN Lab Preprint Alert! 🧬
1/ Genome defence pathway genes are crucial for animal fertility yet often evolve rapidly. We investigated the molecular basis of such rapid evolution in the fly piRNA pathway
TL;DR: protein-protein interaction innovation 💡🤝
🧵👇
www.biorxiv.org/content/10.1...
1/ Genome defence pathway genes are crucial for animal fertility yet often evolve rapidly. We investigated the molecular basis of such rapid evolution in the fly piRNA pathway
TL;DR: protein-protein interaction innovation 💡🤝
🧵👇
www.biorxiv.org/content/10.1...
Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
Despite being essential for fertility, genome defence pathway genes often evolve rapidly. However, little is known about the molecular basis of this adaptation. Here, we characterize the evolution of ...
www.biorxiv.org
October 30, 2024 at 1:57 PM
🧬 New PAN Lab Preprint Alert! 🧬
1/ Genome defence pathway genes are crucial for animal fertility yet often evolve rapidly. We investigated the molecular basis of such rapid evolution in the fly piRNA pathway
TL;DR: protein-protein interaction innovation 💡🤝
🧵👇
www.biorxiv.org/content/10.1...
1/ Genome defence pathway genes are crucial for animal fertility yet often evolve rapidly. We investigated the molecular basis of such rapid evolution in the fly piRNA pathway
TL;DR: protein-protein interaction innovation 💡🤝
🧵👇
www.biorxiv.org/content/10.1...