UW Clinical Trials Institute
@uw-cti.bsky.social
The UW Clinical Trials Institute supports #clinicaltrials participants and #clinicalresearch professionals to advance discovery and help improve #health in #Wisconsin and beyond.
The #FDA approved gepotidacin, an oral antibiotic to treat #gonorrhea. This is the first new treatment approved in over 30 years. buff.ly/vlr1G3k via @medpagetoday.com #clinicaltrials
FDA Approves New Type of Antibiotic for Gonorrhea, First in Decades
Gepotidacin was noninferior to standard care in the phase III EAGLE-1 trial
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December 13, 2025 at 12:33 AM
The #FDA approved gepotidacin, an oral antibiotic to treat #gonorrhea. This is the first new treatment approved in over 30 years. buff.ly/vlr1G3k via @medpagetoday.com #clinicaltrials
2 #HIV mRNA #vaccine #clinicaltrials have produced promising results. buff.ly/U8XgZC8 via @newscientist.com
Human trials point the way towards an mRNA vaccine against HIV
We may be a step closer to a highly effective mRNA vaccine against HIV, but tests so far reveal that the approach can cause unpleasant skin reactions
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December 5, 2025 at 2:58 AM
2 #HIV mRNA #vaccine #clinicaltrials have produced promising results. buff.ly/U8XgZC8 via @newscientist.com
For the first time, a clinical trial will test the effectiveness of a vaccine to prevent fentanyl overdose. buff.ly/gUUZfUf via @wired.com #opioid #addiction #clinicaltrials
A Fentanyl Vaccine Is About to Get Its First Major Test
ARMR Sciences of New York is trialing a vaccine in the Netherlands to protect against fentanyl-related overdose and death.
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December 4, 2025 at 1:24 AM
For the first time, a clinical trial will test the effectiveness of a vaccine to prevent fentanyl overdose. buff.ly/gUUZfUf via @wired.com #opioid #addiction #clinicaltrials
The #FDA recently approved a blood-based test to help diagnose high-grade #prostatecancer and aid in biopsy decisions buff.ly/Tlghh6K via @medpagetoday.com #clinicaltrials
FDA OKs Blood-Based Test to Help Detect High-Grade Prostate Tumors
IsoPSA can provide more information for biopsy decisions
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December 3, 2025 at 1:14 AM
The #FDA recently approved a blood-based test to help diagnose high-grade #prostatecancer and aid in biopsy decisions buff.ly/Tlghh6K via @medpagetoday.com #clinicaltrials
The #FDA could greenlight GLP-1 pills by the end of the year. buff.ly/Xtb81i2 via @npr.org #clinicaltrials #clinicalresearch
5 things to know about the new obesity pills that are on the way
Instead of struggling with weekly injections, patients may soon be able to swallow a daily pill to lose weight. Both the makers of Wegovy and Mounjaro are seeking FDA approval for tablets.
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December 2, 2025 at 12:02 AM
The #FDA could greenlight GLP-1 pills by the end of the year. buff.ly/Xtb81i2 via @npr.org #clinicaltrials #clinicalresearch
Study: Hundreds of #clinicaltrials and tens of thousands of participants were affected by #NIH grant terminations earlier this year. buff.ly/TB0EUi1 via @medpagetoday.com #clinicalresearch
NIH Cuts Disrupted Hundreds of Clinical Trials, Study Finds
Tens of thousands of patients were affected
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November 20, 2025 at 1:24 AM
Study: Hundreds of #clinicaltrials and tens of thousands of participants were affected by #NIH grant terminations earlier this year. buff.ly/TB0EUi1 via @medpagetoday.com #clinicalresearch
A recent study found that the use of annual supplemental multi-#cancer early detection testing led to a 45% decrease in stage IV diagnoses, relative to standard of care. buff.ly/PuBn0IT via @medpagetoday.com #clinicaltrials #clinicalresearch
Multi-Cancer Testing Could Transform Cancer Diagnosis, Study Suggests
The largest absolute reductions were among the most aggressive cancer types
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November 19, 2025 at 1:14 AM
A recent study found that the use of annual supplemental multi-#cancer early detection testing led to a 45% decrease in stage IV diagnoses, relative to standard of care. buff.ly/PuBn0IT via @medpagetoday.com #clinicaltrials #clinicalresearch
#AI is becoming an increasingly important facet of the #clinicaltrials landscape; however, trust in its ability remains a barrier to widespread adoption. buff.ly/PARUNtQ via Clinical Trials Arena #clinicalresearch
Clinical Trials Arena
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November 18, 2025 at 12:02 AM
#AI is becoming an increasingly important facet of the #clinicaltrials landscape; however, trust in its ability remains a barrier to widespread adoption. buff.ly/PARUNtQ via Clinical Trials Arena #clinicalresearch
Promising results from a new #malaria drug offer hope against emerging drug resistance in Africa. buff.ly/UORuUVb via @nature.com #clinicaltrials #clinicalresearch
First new type of malaria treatment in decades shows promise against drug resistance
If approved, GanLum could be available within a year and a half, according to maker.
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November 15, 2025 at 12:33 AM
Promising results from a new #malaria drug offer hope against emerging drug resistance in Africa. buff.ly/UORuUVb via @nature.com #clinicaltrials #clinicalresearch
The #FDA recently launched a “plausible mechanism pathway,” which allows personalized drugs to reach the market sooner for patients with genetic diseases. buff.ly/IiuK41d via Clinical Trials Arena #clinicaltrials #clinicalresearch
Clinical Trials Arena
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November 14, 2025 at 1:20 AM
The #FDA recently launched a “plausible mechanism pathway,” which allows personalized drugs to reach the market sooner for patients with genetic diseases. buff.ly/IiuK41d via Clinical Trials Arena #clinicaltrials #clinicalresearch
Study: Most dermabrasion trials don't report the race of participants, limiting the generalizability of study results. buff.ly/YmDso8a via @medpagetoday.com #dermatology #clinicaltrials #clinicalresearch
Most Dermabrasion Trials Don't Report Race of Participants
Only about 20% of studies analyzed reported on race or skin color
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November 6, 2025 at 1:24 AM
Study: Most dermabrasion trials don't report the race of participants, limiting the generalizability of study results. buff.ly/YmDso8a via @medpagetoday.com #dermatology #clinicaltrials #clinicalresearch
Stronger #biotech funding, fewer trial cancellations, and faster study startup have all led to a surge in global clinical trial initiations in 2025. buff.ly/nog7meb via Clinical Trials Arena #clinicaltrials #clinicalresearch
Clinical Trials Arena
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November 5, 2025 at 1:14 AM
Stronger #biotech funding, fewer trial cancellations, and faster study startup have all led to a surge in global clinical trial initiations in 2025. buff.ly/nog7meb via Clinical Trials Arena #clinicaltrials #clinicalresearch
Despite #AI's initial shortcomings, #regulatory professionals can help adopt the technology for their organizations in a safe and responsible manner. buff.ly/eTjXZTC via Regulatory Focus #clinicaltrials
Embrace AI in regulatory, but ensure humans are ‘in the loop’, experts say
ROTTERDAM, NETHERLANDS @ A panel of experts at RAPS@ European Digital Technology and Software Conference on Thursday urged regulatory professionals to embrace artificial intelligence (AI). They said…
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November 4, 2025 at 12:02 AM
Despite #AI's initial shortcomings, #regulatory professionals can help adopt the technology for their organizations in a safe and responsible manner. buff.ly/eTjXZTC via Regulatory Focus #clinicaltrials
A systematic review of 511 studies showed that #immunization against COVID-19, RSV, and influenza was safe and effective in people of all ages. buff.ly/SDoPaLv via @medpagetoday.com #clinicaltrials #clinicalresearch
Large Review Backs Safety, Effectiveness of COVID, Flu, and RSV Shots
The 511-study analysis is at odds with recent HHS recommendations
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October 31, 2025 at 11:33 PM
A systematic review of 511 studies showed that #immunization against COVID-19, RSV, and influenza was safe and effective in people of all ages. buff.ly/SDoPaLv via @medpagetoday.com #clinicaltrials #clinicalresearch
#FDA proposes ending testing for biosimilars, which are lower-cost versions of complex biologic medicines. buff.ly/JYiRNe1 via @medcitynews.com #clinicaltrials #clinicalresearch
FDA Proposes Dropping Clinical Trial Requirements to Bring Biosimilars to Market More Quickly - MedCity News
Generic drugs don’t need lengthy clinical trials to support a submission seeking FDA approval. The regulator now proposes ending this testing requirement for biosimilars, products that reference…
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October 31, 2025 at 12:20 AM
#FDA proposes ending testing for biosimilars, which are lower-cost versions of complex biologic medicines. buff.ly/JYiRNe1 via @medcitynews.com #clinicaltrials #clinicalresearch
UK researchers have analyzed over 150 #clinicaltrials to compare the side effects of dozens of antidepressants. buff.ly/QgIT9bo via @npr.org #mentalhealth #drug
Antidepressant side effects differ greatly depending on the drug, study finds
Millions of Americans take antidepressants. And like all medication, they come with side effects. Researchers studied 30 different antidepressants and found side effects vary from drug to drug.
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October 29, 2025 at 12:14 AM
UK researchers have analyzed over 150 #clinicaltrials to compare the side effects of dozens of antidepressants. buff.ly/QgIT9bo via @npr.org #mentalhealth #drug
Two recent European studies suggest that #cannabis might be an effective treatment, with fewer side effects, for back pain. buff.ly/Atmkr9e via @npr.org #clinicaltrials #clinicalresearch
Cannabis blunts back pain in 2 new studies
Millions of Americans use weed to treat chronic pain, but there's little high quality research on whether it works. New findings suggest it can be effective for low back pain, on par with opioids.
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October 27, 2025 at 11:02 PM
Two recent European studies suggest that #cannabis might be an effective treatment, with fewer side effects, for back pain. buff.ly/Atmkr9e via @npr.org #clinicaltrials #clinicalresearch
Preliminary research shows that some #cancer patients lived longer if they received the #COVID19 vaccine within 100 days of starting treatment. buff.ly/f8LRGlW via @apnews.com #clinicaltrials
COVID-19 vaccines may help some cancer patients fight tumors
The most widely used COVID-19 vaccines may offer a surprise benefit for some cancer patients by boosting their immune systems to help fight tumors.
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October 23, 2025 at 12:24 AM
Preliminary research shows that some #cancer patients lived longer if they received the #COVID19 vaccine within 100 days of starting treatment. buff.ly/f8LRGlW via @apnews.com #clinicaltrials
#AI agents can help with everyday, low-stakes research tasks. buff.ly/DLiag4H via @nature.com #clinicalresearch #technology
How AI agents will change research: a scientist’s guide
Researchers are increasingly turning to artificial-intelligence tools that can handle complex, multi-step processes.
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October 10, 2025 at 12:20 AM
#AI agents can help with everyday, low-stakes research tasks. buff.ly/DLiag4H via @nature.com #clinicalresearch #technology
Recent changes at the #FDA have changed the circumstances for #raredisease drug development, but this remains an area of opportunity for biotech companies. buff.ly/TBuTXiS via Clinical Trials Arena #clinicaltrials
Clinical Trials Arena
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October 7, 2025 at 11:18 PM
Recent changes at the #FDA have changed the circumstances for #raredisease drug development, but this remains an area of opportunity for biotech companies. buff.ly/TBuTXiS via Clinical Trials Arena #clinicaltrials
The #FDA recently issued product-specific guidance for generic #drug development. buff.ly/M3aB8Wl #clinicaltrials
Product-Specific Guidances for Generic Drug Development
The .gov means it's official.Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
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October 3, 2025 at 12:20 AM
The #FDA recently issued product-specific guidance for generic #drug development. buff.ly/M3aB8Wl #clinicaltrials
Federal #funding cuts have impacted at least 148 #clinicaltrials in the US, affecting over 138k patients. buff.ly/9dhoaJv via @nature.com #clinicalresearch
The damage done - Nature Medicine
When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.
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October 2, 2025 at 12:24 AM
Federal #funding cuts have impacted at least 148 #clinicaltrials in the US, affecting over 138k patients. buff.ly/9dhoaJv via @nature.com #clinicalresearch
Patients with chronic low back pain experienced clinically significant relief when taking an investigational #cannabis extract in a placebo-controlled clinical trial. buff.ly/VO4Pip5 via @medpagetoday.com #clinicaltrials #clinicalresearch
Cannabis Product Beats Placebo for Common Chronic Pain
Phase III trial shows efficacy, but lacks comparison with other active treatments
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September 30, 2025 at 11:18 PM
Patients with chronic low back pain experienced clinically significant relief when taking an investigational #cannabis extract in a placebo-controlled clinical trial. buff.ly/VO4Pip5 via @medpagetoday.com #clinicaltrials #clinicalresearch
Fifty years ago, Dr. Carol Baker proposed vaccinating pregnant women to save babies from a deadly microbe. Now, the idea is finally nearing fruition. buff.ly/X76GcYa via @science.org #clinicaltrials #clinicalresearch
Vaccine given during pregnancy could protect babies from an invisible killer
Shots target group B streptococcus, a little-known microbe that can cause stillbirths and life-threatening disease in infants
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September 26, 2025 at 11:33 PM
Fifty years ago, Dr. Carol Baker proposed vaccinating pregnant women to save babies from a deadly microbe. Now, the idea is finally nearing fruition. buff.ly/X76GcYa via @science.org #clinicaltrials #clinicalresearch
On this Research Administrators Day, we send a heartfelt THANKS to all of the administrative staff within the #clinicalresearch community @uwmadison.bsky.social and @uwhealth.bsky.social who work tirelessly to move medicine forward via #clinicaltrials innovation in #Wisconsin and beyond!
September 26, 2025 at 12:20 AM
On this Research Administrators Day, we send a heartfelt THANKS to all of the administrative staff within the #clinicalresearch community @uwmadison.bsky.social and @uwhealth.bsky.social who work tirelessly to move medicine forward via #clinicaltrials innovation in #Wisconsin and beyond!