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A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein: Cell Reports Medicine www.cell.com/cell-reports...
A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein
Abu-Shmais et al. isolate and characterize respiratory syncytial virus (RSV) and human
metapneumovirus (hMPV) cross-neutralizing antibodies. Structural analysis reveals
one antibody, RM 5-1, binds an ...
www.cell.com
January 20, 2026 at 2:55 PM
A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein: Cell Reports Medicine www.cell.com/cell-reports...
Reposted
A capture assay to analyse immunoglobulin secretion at the single-cell level https://www.biorxiv.org/content/10.64898/2026.01.07.698251v1
January 8, 2026 at 8:18 PM
A capture assay to analyse immunoglobulin secretion at the single-cell level https://www.biorxiv.org/content/10.64898/2026.01.07.698251v1
A vaccine targeting human IgE induces long-term protection against anaphylaxis in humanized mice | Science Translational Medicine www.science.org/doi/10.1126/...
A vaccine targeting human IgE induces long-term protection against anaphylaxis in humanized mice
A conjugate vaccine targeting human IgE induces long-term production of neutralizing antibodies and protects against anaphylaxis in humanized mice.
www.science.org
December 3, 2025 at 9:32 PM
A vaccine targeting human IgE induces long-term protection against anaphylaxis in humanized mice | Science Translational Medicine www.science.org/doi/10.1126/...
B cells and dengue: A cat-and-mouse game | Science Immunology www.science.org/doi/10.1126/...
B cells and dengue: A cat-and-mouse game
Repeated dengue infections elicit broadly neutralizing antibodies that are protective against severe disease.
www.science.org
November 21, 2025 at 9:13 PM
B cells and dengue: A cat-and-mouse game | Science Immunology www.science.org/doi/10.1126/...
B cells targeting parasites capture spatially linked antigens to secure T cell help | Science Immunology www.science.org/doi/10.1126/...
B cells targeting parasites capture spatially linked antigens to secure T cell help
Antigen location orchestrates T cell–B cell collaboration in response to large pathogens.
www.science.org
November 13, 2025 at 4:57 PM
B cells targeting parasites capture spatially linked antigens to secure T cell help | Science Immunology www.science.org/doi/10.1126/...
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development: Immunity www.cell.com/immunity/ful...
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
The dynamics of antigen-specific Tfh responses during extended germinal center reactions
are not well characterized. Marina-Zárate et al. show that vaccine-specific Tfh cells
in the lymph node undergo...
www.cell.com
November 10, 2025 at 2:13 PM
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development: Immunity www.cell.com/immunity/ful...
Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidity | Science Immunology www.science.org/doi/10.1126/...
Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidity
Clonal recruitment is governed by a T cell receptor avidity threshold, whereas probabilistic expansion preserves repertoire polyclonality.
www.science.org
October 17, 2025 at 7:17 PM
Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidity | Science Immunology www.science.org/doi/10.1126/...
Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization | Science Immunology www.science.org/doi/10.1126/...
Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization
SARS-CoV-2 variant booster vaccination broadens human B cell responses through the germinal center reaction.
www.science.org
October 17, 2025 at 7:16 PM
Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization | Science Immunology www.science.org/doi/10.1126/...
Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates | Science Immunology www.science.org/doi/10.1126/...
Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates
Simultaneous immunization with three germline-targeting immunogens primes multiple bnAb lineages in NHPs, advancing multiepitope HIV vaccine strategies.
www.science.org
October 17, 2025 at 7:14 PM
Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates | Science Immunology www.science.org/doi/10.1126/...
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models | Science Immunology www.science.org/doi/10.1126/...
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models
HIV bNAb precursors to multiple epitopes can be primed by germline-targeting mRNA-LNP immunogens in mouse models.
www.science.org
October 17, 2025 at 7:11 PM
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models | Science Immunology www.science.org/doi/10.1126/...
A replicating RNA vaccine protects cynomolgus macaques against lethal clade 2.3.4.4b influenza A H5N1 virus challenge | Science Translational Medicine www.science.org/doi/10.1126/...
A replicating RNA vaccine protects cynomolgus macaques against lethal clade 2.3.4.4b influenza A H5N1 virus challenge
LION-delivered replicating RNA vaccines are immunogenic and protect cynomolgus macaques against lethal influenza A (H5N1) virus challenge.
www.science.org
October 8, 2025 at 7:20 PM
A replicating RNA vaccine protects cynomolgus macaques against lethal clade 2.3.4.4b influenza A H5N1 virus challenge | Science Translational Medicine www.science.org/doi/10.1126/...