Vladimir Heiskanen
@valtsuh.bsky.social
A Finnish dentist. Health blogger. Interested in evidence-based medicine, dentistry, nutrition, metabolism, photobiomodulation therapy etc...
Reposted by Vladimir Heiskanen
Science is sometimes very surprising! Low concentrations of cyanide are generated endogenously in mammalian cells in lysosomes, stimulated by glycine. It is good for mitochondria at low concentrations, but cytotoxic in high conc. --> Cyanide is endogenous transmitter. www.nature.com/articles/s42...
Regulation of mammalian cellular metabolism by endogenous cyanide production - Nature Metabolism
Zuhra and Petrosino et al. report evidence that cyanide acts as a regulatory gasotransmitter in mammalian cells, where it is shown to affect cellular bioenergetics, most likely via protein S-cyanylati...
www.nature.com
March 28, 2025 at 9:27 AM
Science is sometimes very surprising! Low concentrations of cyanide are generated endogenously in mammalian cells in lysosomes, stimulated by glycine. It is good for mitochondria at low concentrations, but cytotoxic in high conc. --> Cyanide is endogenous transmitter. www.nature.com/articles/s42...