@vasculitides
@vasculitides.bsky.social
Living with EGPA/Churg-Strauss Syndrome • NIH-funded researcher • vasculitis patient advocate
www.vasculitides.com
www.vasculitides.com
Pinned
@vasculitides
@vasculitides.bsky.social
· Oct 21
Access our new review on diagnosis, classification, and prognosis of ANCA-associated vasculitis in Nat Rev Rheum for free at rdcu.be/eL3wJ
Pregnancy and delivery in patients with coronary artery lesions and myocardial involvement caused by Kawasaki disease
Pregnancy and delivery in patients with coronary artery lesions and myocardial involvement caused by Kawasaki disease - PubMed
Our purpose was to determine the outcome of pregnancy and delivery in patients with coronary artery lesions and myocardial involvement caused by Kawasaki disease after half a century after the first report of this disease. We investigated 67 deliveries in 39 patients with coronary artery lesions cau …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:20 PM
Pregnancy and delivery in patients with coronary artery lesions and myocardial involvement caused by Kawasaki disease
ANK2-MAVS signaling dysfunction triggers mitochondrial stress and enhances IL-8 mediated inflammatory responses in Takayasu arteritis
ANK2-MAVS signaling dysfunction triggers mitochondrial stress and enhances IL-8 mediated inflammatory responses in Takayasu arteritis - PubMed
Childhood-onset Takayasu arteritis (c-TA) is a severe autoimmune vasculitis with elusive genetic drivers. In this study, the clinical data indicated that c-TA patients exhibited more severe renal stenosis than adult-onset TA (a-TA) patients. Furthermore, whole-exome sequencing of 25 c-TA patients id …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:19 PM
ANK2-MAVS signaling dysfunction triggers mitochondrial stress and enhances IL-8 mediated inflammatory responses in Takayasu arteritis
Estimation of Health Utility Values for Eosinophilic Granulomatosis With Polyangiitis
Estimation of Health Utility Values for Eosinophilic Granulomatosis With Polyangiitis - PubMed
The findings highlight the substantial HRQoL impact of EGPA across all health states, with a higher perceived impact for the relapse and refractory health states. The public and EGPA patient samples produced consistent ratings. This study addresses an evidence gap by characterising health states in …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:19 PM
Estimation of Health Utility Values for Eosinophilic Granulomatosis With Polyangiitis
Quantitative evaluation of myocardial fibrosis in pediatric patients with Kawasaki disease and coronary artery aneurysms by MRI-derived extracellular volume fraction
Quantitative evaluation of myocardial fibrosis in pediatric patients with Kawasaki disease and coronary artery aneurysms by MRI-derived extracellular volume fraction - PubMed
Question Highlights the unmet need for non-invasive fibrosis quantification in KD, as prior methods (e.g., LGE) lack sensitivity for diffuse fibrosis. Findings ECV elevation (size-dependent) in CAAs, along with thrombosis and LGE, serves as an independent predictor of ECV. Clinical relevance Emphasi …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:18 PM
Quantitative evaluation of myocardial fibrosis in pediatric patients with Kawasaki disease and coronary artery aneurysms by MRI-derived extracellular volume fraction
Subacute Infective Endocarditis Misdiagnosed as Polymyalgia Rheumatica: A Case Report
Subacute Infective Endocarditis Misdiagnosed as Polymyalgia Rheumatica: A Case Report - PubMed
Infective endocarditis (IE) is a rare disease with a myriad of signs and symptoms that overlap with other systemic inflammatory disorders. We present the case of an otherwise healthy 57-year-old male patient with a three-month history of back pain, muscle weakness, and weight loss that was initially …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:17 PM
Subacute Infective Endocarditis Misdiagnosed as Polymyalgia Rheumatica: A Case Report
A Case of Palpable Purpura Associated With Japanese Spotted Fever
A Case of Palpable Purpura Associated With Japanese Spotted Fever - PubMed
This report presents the case of a 90-year-old man with Japanese spotted fever (JSF), caused by <i>Rickettsia japonica</i>, who initially manifested high fever, rash, eschar, and lymphadenopathy. After successful antibiotic therapy, he developed palpable purpura similar to IgA vasculitis (IgAV). Pre …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:16 PM
A Case of Palpable Purpura Associated With Japanese Spotted Fever
A rare combination of relapsing polychondritis and systemic lupus erythematosus: a case report
[A rare combination of relapsing polychondritis and systemic lupus erythematosus: a case report] - PubMed
The coexistence of relapsing polychondritis in patients under follow-up for systemic lupus erythematosus is rarely reported in the literature, with a prevalence of about 1%. We here report the first Moroccan case, a 44-year-old female patient who, after nine years of lupus, developed relapsing polyc …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:14 PM
A rare combination of relapsing polychondritis and systemic lupus erythematosus: a case report
Cryoglobulinemic Vasculitis Manifesting as Rapidly Progressive Glomerulonephritis: A Case Report
Cryoglobulinemic Vasculitis Manifesting as Rapidly Progressive Glomerulonephritis: A Case Report - PubMed
Cryoglobulinemic vasculitis is a small- to medium-vessel vasculitis involving the skin, joints, peripheral nerves, and kidneys, due to deposition of immune complexes containing cryoglobulins. Cryoglobulins are immunoglobulins that precipitate below 37°C and are classified into three types: type I (m …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:14 PM
Cryoglobulinemic Vasculitis Manifesting as Rapidly Progressive Glomerulonephritis: A Case Report
Clinical, Biomarker, and Radiological Progression from Asthma to Systemic Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Cohort Study
Clinical, Biomarker, and Radiological Progression from Asthma to Systemic Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Cohort Study - PubMed
In conclusion, the L-EGPA phase may represent a distinct stage in EGPA development that is often challenging to distinguish from refractory asthma. Characterizing this phase and identifying specific biomarkers could facilitate earlier diagnosis and treatment, potentially improving patient outcomes-a …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:13 PM
Clinical, Biomarker, and Radiological Progression from Asthma to Systemic Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Cohort Study
Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica
Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica - PubMed
There is currently no gold standard diagnostic test or validated serological biomarker to monitor disease activity or inform disease prognostication in isolated Polymyalgia Rheumatica (PMR). This presents significant challenges as the diagnosis of PMR is often complicated by multiple disease mimics, …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:12 PM
Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica
The role of radiology in diagnosing synchronous subglottic and mediastinal haemangioma: a rare clinical entity
The role of radiology in diagnosing synchronous subglottic and mediastinal haemangioma: a rare clinical entity - PubMed
Subglottic haemangioma is a rare and life-threatening condition in infancy. A four-month-old girl presented with cough and wheezing with a history of three prior hospitalisations for bronchiolitis and inspiratory stridor. An upper airway endoscopy and imaging, including ultrasonography, CT scan, and …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:11 PM
The role of radiology in diagnosing synchronous subglottic and mediastinal haemangioma: a rare clinical entity
A Real-World Disproportionality Analysis of Avacopan in Anti-Neutrophil Cytoplasmic Antibodies Associated Vasculitis: Insights From FDA Adverse Event Reporting System
A Real-World Disproportionality Analysis of Avacopan in Anti-Neutrophil Cytoplasmic Antibodies Associated Vasculitis: Insights From FDA Adverse Event Reporting System - PubMed
Avacopan, an oral C5a receptor antagonist approved for treating anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis, has established efficacy and short-term safety from clinical trials, but its post-marketing adverse events (AEs) in real-world settings require further characterizatio …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:11 PM
A Real-World Disproportionality Analysis of Avacopan in Anti-Neutrophil Cytoplasmic Antibodies Associated Vasculitis: Insights From FDA Adverse Event Reporting System
A visual guide for emergency radiologists navigating the complexity of abdominal vasculitis: part 1 - true vasculitis
A visual guide for emergency radiologists navigating the complexity of abdominal vasculitis: part 1 - true vasculitis - PubMed
Systemic vasculitides are rare, multi-organ inflammatory disorders involving blood vessels, classified by the size of the affected vessels. When abdominal arteries are involved, diagnosis becomes particularly challenging due to nonspecific symptoms such as fever, fatigue, and abdominal pain, which c …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:10 PM
A visual guide for emergency radiologists navigating the complexity of abdominal vasculitis: part 1 - true vasculitis
Ulcerative colitis complicated by granulomatosis with polyangiitis treated with tacrolimus
Ulcerative colitis complicated by granulomatosis with polyangiitis treated with tacrolimus - PubMed
A 64-year-old woman presented with abdominal pain, upper gastrointestinal bleeding, and purpura on her face and extremities. She had previously been treated with mesalazine for ulcerative colitis. Tests revealed anaemia, elevated inflammatory markers (erythrocyte sedimentation rate, 82 mm/h; C-react …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:10 PM
Ulcerative colitis complicated by granulomatosis with polyangiitis treated with tacrolimus
Response to Commentary on "Factors associated with thrombosis in Behcet Syndrome: A systematic review and meta-analysis"
Response to Commentary on "Factors associated with thrombosis in Behçet Syndrome: A systematic review and meta-analysis" - PubMed
Response to Commentary on "Factors associated with thrombosis in Behçet Syndrome: A systematic review and meta-analysis"
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:09 PM
Response to Commentary on "Factors associated with thrombosis in Behcet Syndrome: A systematic review and meta-analysis"
Tumor Necrosis Factor Inhibitor Therapy in Polyarteritis Nodosa: Expanding Evidence From Systemic to Cutaneous Disease
Tumor Necrosis Factor Inhibitor Therapy in Polyarteritis Nodosa: Expanding Evidence From Systemic to Cutaneous Disease - PubMed
Tumor Necrosis Factor Inhibitor Therapy in Polyarteritis Nodosa: Expanding Evidence From Systemic to Cutaneous Disease
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:09 PM
Tumor Necrosis Factor Inhibitor Therapy in Polyarteritis Nodosa: Expanding Evidence From Systemic to Cutaneous Disease
The MAGIC (Mouth and Genital Ulcers With Inflamed Cartilage) of VEXAS: A Case of Overlap Between Behcet Disease and VEXAS Syndrome
The MAGIC (Mouth and Genital Ulcers With Inflamed Cartilage) of VEXAS: A Case of Overlap Between Behçet Disease and VEXAS Syndrome - PubMed
The MAGIC (Mouth and Genital Ulcers With Inflamed Cartilage) of VEXAS: A Case of Overlap Between Behçet Disease and VEXAS Syndrome
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:08 PM
The MAGIC (Mouth and Genital Ulcers With Inflamed Cartilage) of VEXAS: A Case of Overlap Between Behcet Disease and VEXAS Syndrome
Comment on "An update on stroke and transient ischemic attack in Takayasu arteritis: A systematic review and meta-analysis" by Jin et al. Joint Bone Spine 2026;93:105951*
Comment on "An update on stroke and transient ischemic attack in Takayasu arteritis: A systematic review and meta-analysis" by Jin et al. Joint Bone Spine 2026;93:105951* - PubMed
Comment on "An update on stroke and transient ischemic attack in Takayasu arteritis: A systematic review and meta-analysis" by Jin et al. Joint Bone Spine 2026;93:105951*
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:08 PM
Comment on "An update on stroke and transient ischemic attack in Takayasu arteritis: A systematic review and meta-analysis" by Jin et al. Joint Bone Spine 2026;93:105951*
Role of F-18 FDG-PET CT scan in the evaluation of medium vessel vasculitis
Role of F-18 FDG-PET CT scan in the evaluation of medium vessel vasculitis - PubMed
F-18 FDG PET/CT scans can show characteristic findings in MVV, with predominant involvement of lower extremity vessels and muscle uptake. However, it has limited sensitivity, and this can be further influenced by glucocorticoid use.
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 11:08 PM
Role of F-18 FDG-PET CT scan in the evaluation of medium vessel vasculitis
Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants
Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants - PubMed
While autoantibody levels remained normal, clinical profiles diverged significantly between variants. The Delta variant was associated with heightened systemic inflammation, whereas Omicron was associated with greater organ involvement, suggesting the possibility of distinct pathogenic mechanisms.
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:58 PM
Inflammatory tropism in COVID-19: a comparative analysis of Delta and Omicron variants
Epidemiological Characterization of Uveitis in Pediatric Population: A Systematic Review and Meta Analysis
Epidemiological Characterization of Uveitis in Pediatric Population: A Systematic Review and Meta Analysis - PubMed
Pediatric uveitis is a leading cause of visual impairment, often resulting in severe complications without timely and appropriate intervention. Its etiology varies geographically, necessitating a comprehensive epidemiological assessment. To identify prevalent causes of pediatric uveitis, assess geog …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:57 PM
Epidemiological Characterization of Uveitis in Pediatric Population: A Systematic Review and Meta Analysis
Early-stage cost-utility analysis of novel diagnostic tests for giant cell arteritis: a modelling study in UK secondary care
Early-stage cost-utility analysis of novel diagnostic tests for giant cell arteritis: a modelling study in UK secondary care - PubMed
The study highlights the potential for hypothetical tests to improve GCA diagnosis and reduce glucocorticoid toxicity, while demonstrating their market viability for use within the NHS. It also illustrates how early-stage economic models can provide valuable insights into potential cost-effectivenes …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:57 PM
Early-stage cost-utility analysis of novel diagnostic tests for giant cell arteritis: a modelling study in UK secondary care
Acute necrotising pancreatitis in a patient with Behcet's disease
Acute necrotising pancreatitis in a patient with Behçet's disease - PubMed
A man in his 40s of Middle Eastern descent, with no prior medical history, presented with severe abdominal pain that had progressed over 2 days. He was diagnosed with acute necrotising pancreatitis, multifocal venous thromboembolism and acute kidney injury, requiring admission to the intensive care …
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:56 PM
Acute necrotising pancreatitis in a patient with Behcet's disease
PAI-1 promotes thromboangiitis obliterans progression through NF-κB-NLRP3 pathway activation via HIF-1α-dependent signaling
PAI-1 promotes thromboangiitis obliterans progression through NF-κB-NLRP3 pathway activation via HIF-1α-dependent signaling - PubMed
PAI-1 promotes the progression of TAO by activating the NF-κB pathway via HIF-1α. Targeted inhibition of PAI-1 represents a potential therapeutic strategy for TAO.
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:56 PM
PAI-1 promotes thromboangiitis obliterans progression through NF-κB-NLRP3 pathway activation via HIF-1α-dependent signaling
Coronary Vasospasm in Eosinophilic Granulomatosis With Polyangiitis Presenting as Acute Coronary Syndrome Treated With Anti-IL-5
Coronary Vasospasm in Eosinophilic Granulomatosis With Polyangiitis Presenting as Acute Coronary Syndrome Treated With Anti-IL-5 - PubMed
EGPA should be considered in recurrent acute coronary syndrome with eosinophilia. Benralizumab offers a steroid-sparing strategy in cardiac EGPA.
pubmed.ncbi.nlm.nih.gov
November 19, 2025 at 10:55 PM
Coronary Vasospasm in Eosinophilic Granulomatosis With Polyangiitis Presenting as Acute Coronary Syndrome Treated With Anti-IL-5