@viciousbeans.bsky.social
I don't repost things to steal credit , or get likes. The things i repost , i believe need to be seen, so i help spread them. Because i have to do something..even if it's just this. ... Unless its about my dog..like the hell out of her o3 o
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In frontline Kramatorsk — a city under constant russian aggression — children refuse to give in to terror❤️
A snowball fight is the only kind of battle kids should experience❄️
A snowball fight is the only kind of battle kids should experience❄️
December 30, 2025 at 3:20 PM
In frontline Kramatorsk — a city under constant russian aggression — children refuse to give in to terror❤️
A snowball fight is the only kind of battle kids should experience❄️
A snowball fight is the only kind of battle kids should experience❄️
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USPS quietly changed its postmark rules — mail is no longer dated when you drop it off. The “official” date is when it hits automated sorting — sometimes days later
Which could have major implications for mail in voting — it’s a clever way to disenfranchise voters that’s going largely overlooked
Which could have major implications for mail in voting — it’s a clever way to disenfranchise voters that’s going largely overlooked
December 30, 2025 at 2:03 AM
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Have you seen my bell?🛎️
ベルがどこかにいっちゃいましたっ☆音は聞こえるんですがどこですかっ
ベルがどこかにいっちゃいましたっ☆音は聞こえるんですがどこですかっ
December 29, 2025 at 12:34 PM
Have you seen my bell?🛎️
ベルがどこかにいっちゃいましたっ☆音は聞こえるんですがどこですかっ
ベルがどこかにいっちゃいましたっ☆音は聞こえるんですがどこですかっ
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blood-brain barrier breakdown, nerve damage, and behavioral changes similar to those seen in people. When P7C3-A20 was given before symptoms began, it prevented disease features. More striking was what happened when treatment started later. Mice with advanced disease REGAINED normal NAD+ balance.
December 28, 2025 at 5:08 PM
blood-brain barrier breakdown, nerve damage, and behavioral changes similar to those seen in people. When P7C3-A20 was given before symptoms began, it prevented disease features. More striking was what happened when treatment started later. Mice with advanced disease REGAINED normal NAD+ balance.
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above safe levels, unlike some over-the-counter supplements. To model Alzheimer’s, researchers used two types of mice. One carried human mutations linked to amyloid buildup. The other carried a human mutation in tau, another hallmark of the disease. Both models developed memory loss, inflammation,
December 28, 2025 at 5:07 PM
above safe levels, unlike some over-the-counter supplements. To model Alzheimer’s, researchers used two types of mice. One carried human mutations linked to amyloid buildup. The other carried a human mutation in tau, another hallmark of the disease. Both models developed memory loss, inflammation,
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worsened as disease progressed. The team decided to focus on restoring NAD+ homeostasis (meaning healthy balance rather than excessive levels). They used a compound called P7C3-A20, developed in their lab, which helps cells maintain normal NAD+ under stress. Importantly, it does not push NAD+
December 28, 2025 at 5:07 PM
worsened as disease progressed. The team decided to focus on restoring NAD+ homeostasis (meaning healthy balance rather than excessive levels). They used a compound called P7C3-A20, developed in their lab, which helps cells maintain normal NAD+ under stress. Importantly, it does not push NAD+
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In Alzheimer’s, the drop is sharper and more damaging. By examining human Alzheimer’s brains AND engineered mouse models, researchers observed that NAD+ balance was SEVERELY disrupted. Cells could no longer meet energy demands or defend themselves against stress. This failure appeared early and
December 28, 2025 at 5:06 PM
In Alzheimer’s, the drop is sharper and more damaging. By examining human Alzheimer’s brains AND engineered mouse models, researchers observed that NAD+ balance was SEVERELY disrupted. Cells could no longer meet energy demands or defend themselves against stress. This failure appeared early and
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important? Nicotinamide adenine dinucleotide, or NAD+, helps cells turn nutrients into energy and repair daily damage. It supports DNA repair, controls inflammation, protects the blood-brain barrier, and keeps nerve cells connected. As you age, NAD+ levels decline throughout the body.
December 28, 2025 at 5:05 PM
important? Nicotinamide adenine dinucleotide, or NAD+, helps cells turn nutrients into energy and repair daily damage. It supports DNA repair, controls inflammation, protects the blood-brain barrier, and keeps nerve cells connected. As you age, NAD+ levels decline throughout the body.
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Institute at University Hospitals. He also holds faculty appointments at Case Western Reserve University and serves as a clinician-scientist at the Cleveland VA. Together, the team set out to test an idea rarely explored in Alzheimer’s research: recovery.
So, what exactly is NAD+? And why is it so
So, what exactly is NAD+? And why is it so
December 28, 2025 at 5:05 PM
Institute at University Hospitals. He also holds faculty appointments at Case Western Reserve University and serves as a clinician-scientist at the Cleveland VA. Together, the team set out to test an idea rarely explored in Alzheimer’s research: recovery.
So, what exactly is NAD+? And why is it so
So, what exactly is NAD+? And why is it so
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HUMAN brain tissue, researchers found that restoring balance to a central cellular energy molecule, NAD+, not only prevented disease features but reversed them, even at late stages. The senior author, Andrew A. Pieper, MD, PhD, directs the Brain Health Medicines Center at the Harrington Discovery
December 28, 2025 at 5:04 PM
HUMAN brain tissue, researchers found that restoring balance to a central cellular energy molecule, NAD+, not only prevented disease features but reversed them, even at late stages. The senior author, Andrew A. Pieper, MD, PhD, directs the Brain Health Medicines Center at the Harrington Discovery
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Hospitals, Case Western Reserve University, and the Louis Stokes Cleveland VA Medical Center report evidence that challenges this assumption. The study, published in Cell Reports Medicine, tested whether brains with advanced Alzheimer’s-like damage could recover. Using multiple mouse models and
December 28, 2025 at 5:04 PM
Hospitals, Case Western Reserve University, and the Louis Stokes Cleveland VA Medical Center report evidence that challenges this assumption. The study, published in Cell Reports Medicine, tested whether brains with advanced Alzheimer’s-like damage could recover. Using multiple mouse models and
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For more than a century, Alzheimer’s disease has been framed as irreversible. Once memory and thinking decline, recovery has not been considered possible. That belief shaped nearly all research, which focused on prevention or slowing damage, not repairing it. Now, researchers from University
December 28, 2025 at 5:04 PM
For more than a century, Alzheimer’s disease has been framed as irreversible. Once memory and thinking decline, recovery has not been considered possible. That belief shaped nearly all research, which focused on prevention or slowing damage, not repairing it. Now, researchers from University
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In preclinical models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer’s biomarkers (in HUMAN models as well).
• case.edu/news/new-stu...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
• case.edu/news/new-stu...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
December 28, 2025 at 5:03 PM
In preclinical models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer’s biomarkers (in HUMAN models as well).
• case.edu/news/new-stu...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
• case.edu/news/new-stu...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
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You can read all this and more here:
• www.cell.com/cell-reports...
• case.edu/news/new-stu...
• www.eurekalert.org/news-release...
• neurosciencenews.com/alzheimers-r...
• www.sciencedaily.com/releases/202...
• medicalresearch.com/case-western...
• www.psypost.org/scientists-a...
• www.cell.com/cell-reports...
• case.edu/news/new-stu...
• www.eurekalert.org/news-release...
• neurosciencenews.com/alzheimers-r...
• www.sciencedaily.com/releases/202...
• medicalresearch.com/case-western...
• www.psypost.org/scientists-a...
December 28, 2025 at 5:50 PM
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The approach tested here restores balance without pushing levels too high, an important safety distinction. If confirmed in humans, therapies aimed at NAD+ homeostasis could influence treatment strategies for Alzheimer’s and other age-related brain diseases.
December 28, 2025 at 5:14 PM
The approach tested here restores balance without pushing levels too high, an important safety distinction. If confirmed in humans, therapies aimed at NAD+ homeostasis could influence treatment strategies for Alzheimer’s and other age-related brain diseases.
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GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages.
December 28, 2025 at 5:00 PM
GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages.
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Today, on International Cinema Day, we remember the professionals of Ukrainian film production who gave their lives defending Ukraine against russian aggression.They could have continued to create, to tell stories, and to enrich Ukrainian culture, but they were killed by russia.
Remembered forever💔
Remembered forever💔
December 28, 2025 at 4:11 PM
Today, on International Cinema Day, we remember the professionals of Ukrainian film production who gave their lives defending Ukraine against russian aggression.They could have continued to create, to tell stories, and to enrich Ukrainian culture, but they were killed by russia.
Remembered forever💔
Remembered forever💔
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New Year’s resolutions quest, Day 2.🎅
We’ve almost achieved the 1st goal.🔥
💙Dark Night—$449,826
💛Sky Sentinel—$2,886,829
🦇Simone G won the Dark Night tee
Our 3rd NAFO turret is almost there, and we came close to 20 turrets overall.
Let’s do this:
u24.gov.ua/nafo-dark-ni...
We’ve almost achieved the 1st goal.🔥
💙Dark Night—$449,826
💛Sky Sentinel—$2,886,829
🦇Simone G won the Dark Night tee
Our 3rd NAFO turret is almost there, and we came close to 20 turrets overall.
Let’s do this:
u24.gov.ua/nafo-dark-ni...
December 28, 2025 at 7:01 PM
New Year’s resolutions quest, Day 2.🎅
We’ve almost achieved the 1st goal.🔥
💙Dark Night—$449,826
💛Sky Sentinel—$2,886,829
🦇Simone G won the Dark Night tee
Our 3rd NAFO turret is almost there, and we came close to 20 turrets overall.
Let’s do this:
u24.gov.ua/nafo-dark-ni...
We’ve almost achieved the 1st goal.🔥
💙Dark Night—$449,826
💛Sky Sentinel—$2,886,829
🦇Simone G won the Dark Night tee
Our 3rd NAFO turret is almost there, and we came close to 20 turrets overall.
Let’s do this:
u24.gov.ua/nafo-dark-ni...
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@////////@ NOMNOMNOMNOMNOMNOM
December 28, 2025 at 1:56 AM
@////////@ NOMNOMNOMNOMNOMNOM
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Filming them committing terrorism is now itself an act of terrorism?
December 27, 2025 at 7:06 PM
Filming them committing terrorism is now itself an act of terrorism?