Vicky Tan
@vickytan.bsky.social
490 followers
190 following
6 posts
Postdoc in the White Lab (Ludwig Cancer Research/Uni of Oxford). I am interested in how melanin's electrical properties may influence cell-cell communication and melanoma initiation. Alum of Cox and Dawson Labs (Peter Mac/Uni of Melbourne).
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Vicky Tan
@vickytan.bsky.social
· Jan 5
Mark Dawson
@mafdawson.bsky.social
· Jan 2
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.
www.cell.com