victorsimon.bsky.social
@victorsimon.bsky.social
Reposted
New Review: Florence Hommais and coworkers explore how small RNAs (sRNAs) regulate nucleoid-associated proteins (NAPs), how NAPs regulate sRNAs, as well as the role of sRNAs in nucleoid structuring.
#MicroSky #Chromatin #sRNA
onlinelibrary.wiley.com/doi/10.1111/...
The Power Duo: How the Interplay Between Nucleoid‐Associated Proteins and Small Noncoding RNAs Orchestrates the Cellular Regulatory Symphony
Nucleoid-associated proteins play a crucial role in the compaction of bacterial DNA and the regulation of gene expression. The emergence of small noncoding RNAs as regulatory elements in these proces....
onlinelibrary.wiley.com
April 6, 2025 at 1:06 PM
Reposted
Simon et al. explore the the Roc (regulation of cup) two-component systems in P. aeruginosa, including two histidine kinases (RocS1 and RocS2) and (now) 5 response regulators that regulate virulence, antibiotic resistance, and biofilm formation.
#MicroSky

onlinelibrary.wiley.com/doi/10.1111/...
Functional and Pangenomic Exploration of Roc Two‐Component Regulatory Systems Identifies Novel Players Across Pseudomonas Species
The Roc system represents a highly interconnected but incomplete network of two-component regulatory systems involved in the virulence of Pseudomonas aeruginosa. Our work has enabled us to identify t....
onlinelibrary.wiley.com
March 18, 2025 at 2:28 PM