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Ville Paakinaho

@villepaakinaho.bsky.social

26 followers 29 following 9 posts

PhD. Academy Research Fellow @uniuef.bsky.social. My research group investigates transcription factor crosstalk in cancers.

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Ville Paakinaho @villepaakinaho.bsky.social · 9d

Few days left to submit an abstract to the Annual Meeting of the Finnish Endocrine Society.

Ville Paakinaho @villepaakinaho.bsky.social · Aug 21

The upcoming Annual Finnish Endocrine Society meeting has excellent Scientific sessions on the 30th of October. Please see the attachment for more information.

Ville Paakinaho @villepaakinaho.bsky.social · Aug 25

Our new preprint is out.

p63-GATA2 molecular switch mediates the tumor suppressor to oncogene transition of glucocorticoid receptor in the prostate.

www.biorxiv.org/content/10.1...

p63-GATA2 molecular switch mediates the tumor suppressor to oncogene transition of glucocorticoid receptor in the prostate

Although glucocorticoids are widely used to alleviate side effects of prostate cancer (PCa) treatment, the glucocorticoid receptor (GR) exhibits a dual role exerting tumor-suppressive effects by inhib...

www.biorxiv.org

Ville Paakinaho @villepaakinaho.bsky.social · Aug 21

The upcoming Annual Finnish Endocrine Society meeting has excellent Scientific sessions on the 30th of October. Please see the attachment for more information.

Ville Paakinaho @villepaakinaho.bsky.social · Aug 12

The new Leydig Cells book features a chapter written by us

The Androgen Receptor: Key to Testosterone Function and Androgen Sensitivity

doi.org/10.1007/978-...

The Androgen Receptor: Key to Testosterone Function and Androgen Sensitivity

Androgens, vital for male sexual development and behavior, function through the androgen receptor (AR), a transcription factor controlled by testosterone and 5α-dihydrotestosterone. AR’s ac...

doi.org

Ville Paakinaho @villepaakinaho.bsky.social · Jun 3

Happy to share that our latest research study is out now @genomeresearch.bsky.social

Androgen receptor-mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

genome.cshlp.org/content/earl...

pubmed.ncbi.nlm.nih.gov/40456604/

Androgen receptor-mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms

genome.cshlp.org

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Ville Paakinaho @villepaakinaho.bsky.social · Apr 24

It’s the #WorldHormoneDay

My research group @uniuef.bsky.social investigates hormones and their role in endocrine-related diseases

#BecauseHormonesMatter

Ville Paakinaho @villepaakinaho.bsky.social · Apr 24

Tänään vietetään maailman hormonipäivää! Tutkimusryhmäni Itä-Suomen yliopistossa (@uniuef.bsky.social) tutkii hormonien toimintaa erilaisissa taudeissa.

#BecauseHormonesMatter

Ville Paakinaho @villepaakinaho.bsky.social · Feb 17

Thanks Eva!

Ville Paakinaho @villepaakinaho.bsky.social · Feb 17

Out now at Oncogene

SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells
www.nature.com/articles/s41...

SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells - Oncogene

Oncogene - SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells

www.nature.com

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Reposted by Ville Paakinaho

bioRxiv Genomics @biorxiv-genomic.bsky.social · Nov 16

Steroid receptor-assisted loading modulates transcriptional responses in prostate cancer cells https://www.biorxiv.org/content/10.1101/2024.11.15.623719v1

Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biologi

www.biorxiv.org

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