Vincent Van Deuren
@vincentvandeuren.bsky.social
Postdoc at Dedecker Lab
Protein engineer
Protein engineer
Reposted by Vincent Van Deuren
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Synthetic fluorophores for live-cell fluorescence microscopy and biosensing - Nature Chemical Biology
Performing live-cell microscopy experiments with high spatial and temporal resolution requires fluorophores with highly optimized properties. This Review examines the progress in developing synthetic ...
www.nature.com
November 5, 2025 at 9:29 PM
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Reposted by Vincent Van Deuren
New preprint! Our work together with @agtebo.bsky.social : our 'NanoBlocks' strategy to generate fluorescent biosensors from binders such as nanobodies. Proof-of-concept sensors with ALFA nanobody & Erbin PDZ domain shows the concept in vitro, in cells, and for FACS.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
NanoBlocks: creating fluorescent biosensors from affinity binders using competitive binding
Genetically-encoded fluorescent biosensors have revolutionized our understanding of complex systems by permitting the in situ observation of chemical activities. However, only a comparatively small se...
www.biorxiv.org
October 29, 2025 at 1:33 PM
New preprint! Our work together with @agtebo.bsky.social : our 'NanoBlocks' strategy to generate fluorescent biosensors from binders such as nanobodies. Proof-of-concept sensors with ALFA nanobody & Erbin PDZ domain shows the concept in vitro, in cells, and for FACS.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
🚨New preprint 🚨Our 'NanoBlocks' strategy to generate fluorescent biosensors from binders such as nanobodies. Proof-of-concept sensors with ALFA nanobody & Erbin PDZ domain shows the concept in vitro, in cells, and for FACS. Have an antibody-like binder? Turn it into a biosensor using NanoBlocks.
October 30, 2025 at 8:23 AM
🚨New preprint 🚨Our 'NanoBlocks' strategy to generate fluorescent biosensors from binders such as nanobodies. Proof-of-concept sensors with ALFA nanobody & Erbin PDZ domain shows the concept in vitro, in cells, and for FACS. Have an antibody-like binder? Turn it into a biosensor using NanoBlocks.
Do you want to do nanoscale ratiometric fluorescence imaging? Make sure to account for point-spread-function (PSF) mismatch between emission channels! The differences in image formation causes the appearance of spurious structuring, resulting in misleading ratiometric images
June 23, 2025 at 2:19 PM
Do you want to do nanoscale ratiometric fluorescence imaging? Make sure to account for point-spread-function (PSF) mismatch between emission channels! The differences in image formation causes the appearance of spurious structuring, resulting in misleading ratiometric images
Reposted by Vincent Van Deuren
🚨 Want a fast confocal? Struggling to capture dynamics in 3D? Lacking a system capable of 3D DNA-PAINT imaging 🧬✨?
TriScan – a single-molecule sensitive line-scan confocal with the speed of a widefield!
Preprint: biorxiv.org/content/10.1101/2023.04.11.536163v2
#Microscopy #DNApaint #Confocal
TriScan – a single-molecule sensitive line-scan confocal with the speed of a widefield!
Preprint: biorxiv.org/content/10.1101/2023.04.11.536163v2
#Microscopy #DNApaint #Confocal
April 25, 2025 at 8:07 AM
🚨 Want a fast confocal? Struggling to capture dynamics in 3D? Lacking a system capable of 3D DNA-PAINT imaging 🧬✨?
TriScan – a single-molecule sensitive line-scan confocal with the speed of a widefield!
Preprint: biorxiv.org/content/10.1101/2023.04.11.536163v2
#Microscopy #DNApaint #Confocal
TriScan – a single-molecule sensitive line-scan confocal with the speed of a widefield!
Preprint: biorxiv.org/content/10.1101/2023.04.11.536163v2
#Microscopy #DNApaint #Confocal