William Sessions
@william.maxoutput.ai
Creating clinical research site automations. CEO & Co-Founder @MaxOutput. Building systems that eliminate the manual chaos site staff deal with daily.
Pinned
I've been a yacht deckhand, an SDR who 6x'd the sales record, and a CEO of a hardware startup. Now I build automation for clinical research sites. The through-line? Systems thinking. (1/4)
Clinical sites are drowning in protocol amendments.
Each one triggers 50+ manual tasks across spreadsheets, binders, and email chains.
We're building something that turns that into 3 clicks.
Admin burden shouldn't be the bottleneck to life-saving research.
#ClinicalResearch #ScienceFeed
Each one triggers 50+ manual tasks across spreadsheets, binders, and email chains.
We're building something that turns that into 3 clicks.
Admin burden shouldn't be the bottleneck to life-saving research.
#ClinicalResearch #ScienceFeed
January 12, 2026 at 11:12 PM
Clinical sites are drowning in protocol amendments.
Each one triggers 50+ manual tasks across spreadsheets, binders, and email chains.
We're building something that turns that into 3 clicks.
Admin burden shouldn't be the bottleneck to life-saving research.
#ClinicalResearch #ScienceFeed
Each one triggers 50+ manual tasks across spreadsheets, binders, and email chains.
We're building something that turns that into 3 clicks.
Admin burden shouldn't be the bottleneck to life-saving research.
#ClinicalResearch #ScienceFeed
Sunday reset: This week I'm obsessed with one question.
How much expertise gets wasted because smart people are drowning in admin work they shouldn't be doing?
We're building the answer. More soon.
How much expertise gets wasted because smart people are drowning in admin work they shouldn't be doing?
We're building the answer. More soon.
January 11, 2026 at 11:14 PM
Sunday reset: This week I'm obsessed with one question.
How much expertise gets wasted because smart people are drowning in admin work they shouldn't be doing?
We're building the answer. More soon.
How much expertise gets wasted because smart people are drowning in admin work they shouldn't be doing?
We're building the answer. More soon.
Spent Sunday morning debugging an n8n workflow that was supposed to save time.
The irony isn't lost on me.
But that's the thing about good systems - they cost upfront to build right. Most people quit here and stay buried in admin work forever.
#MDSky
The irony isn't lost on me.
But that's the thing about good systems - they cost upfront to build right. Most people quit here and stay buried in admin work forever.
#MDSky
January 10, 2026 at 11:13 PM
Spent Sunday morning debugging an n8n workflow that was supposed to save time.
The irony isn't lost on me.
But that's the thing about good systems - they cost upfront to build right. Most people quit here and stay buried in admin work forever.
#MDSky
The irony isn't lost on me.
But that's the thing about good systems - they cost upfront to build right. Most people quit here and stay buried in admin work forever.
#MDSky
First week of 2026: creating an automation that could save 40+ hours/month.
The pattern I keep seeing? Teams know _exactly_ what's broken. They just need someone to actually build the fix.
Systems over suffering.
#MSky #ClinicalResearch
The pattern I keep seeing? Teams know _exactly_ what's broken. They just need someone to actually build the fix.
Systems over suffering.
#MSky #ClinicalResearch
January 9, 2026 at 11:14 PM
First week of 2026: creating an automation that could save 40+ hours/month.
The pattern I keep seeing? Teams know _exactly_ what's broken. They just need someone to actually build the fix.
Systems over suffering.
#MSky #ClinicalResearch
The pattern I keep seeing? Teams know _exactly_ what's broken. They just need someone to actually build the fix.
Systems over suffering.
#MSky #ClinicalResearch
FDA's ramping up inspections with AI-driven site targeting.
Translation: If your systems look messy on paper, you're getting flagged before they even show up.
Most sites scramble after the notice. Smart ones are fixing their documentation systems now.
#ClinicalResearch #ScienceFeed
Translation: If your systems look messy on paper, you're getting flagged before they even show up.
Most sites scramble after the notice. Smart ones are fixing their documentation systems now.
#ClinicalResearch #ScienceFeed
January 8, 2026 at 11:13 PM
FDA's ramping up inspections with AI-driven site targeting.
Translation: If your systems look messy on paper, you're getting flagged before they even show up.
Most sites scramble after the notice. Smart ones are fixing their documentation systems now.
#ClinicalResearch #ScienceFeed
Translation: If your systems look messy on paper, you're getting flagged before they even show up.
Most sites scramble after the notice. Smart ones are fixing their documentation systems now.
#ClinicalResearch #ScienceFeed
Clinical research coordinators: 35-61% turnover rate. 7 open jobs for every 1 candidate.
The industry keeps hiring faster instead of asking why people leave.
You can't recruit your way out of broken systems. #ClinicalResearch #ScienceFeed
The industry keeps hiring faster instead of asking why people leave.
You can't recruit your way out of broken systems. #ClinicalResearch #ScienceFeed
January 7, 2026 at 11:14 PM
Clinical research coordinators: 35-61% turnover rate. 7 open jobs for every 1 candidate.
The industry keeps hiring faster instead of asking why people leave.
You can't recruit your way out of broken systems. #ClinicalResearch #ScienceFeed
The industry keeps hiring faster instead of asking why people leave.
You can't recruit your way out of broken systems. #ClinicalResearch #ScienceFeed
2026 is about to hit clinical research sites hard.
2026 is about to hit clinical research sites hard.
Check out the latest newsletter
open.substack.com
January 6, 2026 at 11:14 PM
2026 is about to hit clinical research sites hard.
#MedSky #ClinicalResearch
January 5, 2026 at 11:14 PM
#MedSky #ClinicalResearch
Sunday ritual: roadmap review
Mapping Q1 for Max Output. Building workflow tools for clinical sites - the kind that eliminate steps instead of just digitizing chaos.
What are you tackling this quarter?
#MSky #ClinicalResearch
Mapping Q1 for Max Output. Building workflow tools for clinical sites - the kind that eliminate steps instead of just digitizing chaos.
What are you tackling this quarter?
#MSky #ClinicalResearch
January 4, 2026 at 11:14 PM
Sunday ritual: roadmap review
Mapping Q1 for Max Output. Building workflow tools for clinical sites - the kind that eliminate steps instead of just digitizing chaos.
What are you tackling this quarter?
#MSky #ClinicalResearch
Mapping Q1 for Max Output. Building workflow tools for clinical sites - the kind that eliminate steps instead of just digitizing chaos.
What are you tackling this quarter?
#MSky #ClinicalResearch
Question for everyone running clinical trials:
What's the ONE system at your site that makes you think "there has to be a better way to do this" every single time you use it?
(Asking because I'm curious what patterns show up across sites)
#ClinicalResearch #MedSky
What's the ONE system at your site that makes you think "there has to be a better way to do this" every single time you use it?
(Asking because I'm curious what patterns show up across sites)
#ClinicalResearch #MedSky
January 3, 2026 at 11:13 PM
Question for everyone running clinical trials:
What's the ONE system at your site that makes you think "there has to be a better way to do this" every single time you use it?
(Asking because I'm curious what patterns show up across sites)
#ClinicalResearch #MedSky
What's the ONE system at your site that makes you think "there has to be a better way to do this" every single time you use it?
(Asking because I'm curious what patterns show up across sites)
#ClinicalResearch #MedSky
Clinical research runs on 47 different systems that don't talk to each other.
Then everyone wonders why coordinators spend 60% of their time on data entry instead of patients.
You don't have a staffing problem. You have a systems problem.
#ClinicalResearch #ScienceFeed
Then everyone wonders why coordinators spend 60% of their time on data entry instead of patients.
You don't have a staffing problem. You have a systems problem.
#ClinicalResearch #ScienceFeed
January 2, 2026 at 11:13 PM
Clinical research runs on 47 different systems that don't talk to each other.
Then everyone wonders why coordinators spend 60% of their time on data entry instead of patients.
You don't have a staffing problem. You have a systems problem.
#ClinicalResearch #ScienceFeed
Then everyone wonders why coordinators spend 60% of their time on data entry instead of patients.
You don't have a staffing problem. You have a systems problem.
#ClinicalResearch #ScienceFeed
What's the one system you're finally fixing in 2026?
Not a goal. Not a habit. The actual broken process that wastes your team's time every single week.
I'll go first: redundant data entry between our CRM and project tracker.
#MedSky #ClinicalResearch
Not a goal. Not a habit. The actual broken process that wastes your team's time every single week.
I'll go first: redundant data entry between our CRM and project tracker.
#MedSky #ClinicalResearch
January 1, 2026 at 11:14 PM
What's the one system you're finally fixing in 2026?
Not a goal. Not a habit. The actual broken process that wastes your team's time every single week.
I'll go first: redundant data entry between our CRM and project tracker.
#MedSky #ClinicalResearch
Not a goal. Not a habit. The actual broken process that wastes your team's time every single week.
I'll go first: redundant data entry between our CRM and project tracker.
#MedSky #ClinicalResearch
The research sites who shared their workflow headaches this year shaped everything we're building.
You showed us where the real bottlenecks are. Where good people lose hours to bad systems.
That honesty is what drives better solutions.
Thank you.
#ClinicalResearch #ScienceFeed
You showed us where the real bottlenecks are. Where good people lose hours to bad systems.
That honesty is what drives better solutions.
Thank you.
#ClinicalResearch #ScienceFeed
December 31, 2025 at 11:14 PM
The research sites who shared their workflow headaches this year shaped everything we're building.
You showed us where the real bottlenecks are. Where good people lose hours to bad systems.
That honesty is what drives better solutions.
Thank you.
#ClinicalResearch #ScienceFeed
You showed us where the real bottlenecks are. Where good people lose hours to bad systems.
That honesty is what drives better solutions.
Thank you.
#ClinicalResearch #ScienceFeed
Dug into 2025 site ops data this week. 38% cite protocol complexity as top challenge. Not recruitment. Complexity.
Dug into 2025 site ops data this week. 38% cite pr
Check out the latest newsletter
open.substack.com
December 31, 2025 at 5:05 AM
Dug into 2025 site ops data this week. 38% cite protocol complexity as top challenge. Not recruitment. Complexity.
We've been building something different for 2026.
Clinical research teams spending 60% of their time on admin work isn't normal. It's fixable.
More soon.
#ClinicalResearch #MSky
Clinical research teams spending 60% of their time on admin work isn't normal. It's fixable.
More soon.
#ClinicalResearch #MSky
December 30, 2025 at 1:08 AM
We've been building something different for 2026.
Clinical research teams spending 60% of their time on admin work isn't normal. It's fixable.
More soon.
#ClinicalResearch #MSky
Clinical research teams spending 60% of their time on admin work isn't normal. It's fixable.
More soon.
#ClinicalResearch #MSky
2026 is the year clinical research teams stop tolerating admin chaos.
Not because they found more budget. Because they finally realized their best people are spending 60% of their time on work a system should handle.
The talent shortage isn't real. The systems shortage is.
Not because they found more budget. Because they finally realized their best people are spending 60% of their time on work a system should handle.
The talent shortage isn't real. The systems shortage is.
December 29, 2025 at 1:13 AM
2026 is the year clinical research teams stop tolerating admin chaos.
Not because they found more budget. Because they finally realized their best people are spending 60% of their time on work a system should handle.
The talent shortage isn't real. The systems shortage is.
Not because they found more budget. Because they finally realized their best people are spending 60% of their time on work a system should handle.
The talent shortage isn't real. The systems shortage is.
Spent the morning teaching Sarah a few n8n workflow over hot cocoa.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
December 27, 2025 at 4:27 AM
Spent the morning teaching Sarah a few n8n workflow over hot cocoa.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Watching a clinical ops pro light up when she sees admin work disappear in real-time never gets old.
This is why we built Max Output.
Grateful for the humans who made this year worth it.
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
December 25, 2025 at 1:07 AM
Grateful for the humans who made this year worth it.
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
Everyone who trusted us with their chaos.
Merry Christmas to those celebrating. 🎄
To everyone in clinical research working through the holidays: your work matters more than most people realize.
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
December 23, 2025 at 9:47 AM
To everyone in clinical research working through the holidays: your work matters more than most people realize.
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Trials don't pause. Patients can't wait. You show up anyway.
Thank you.
#ClinicalResearch #ScienceFeed
Most site managers are one resignation away from chaos, because every process lives in someone's head.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
December 22, 2025 at 7:24 PM
Most site managers are one resignation away from chaos, because every process lives in someone's head.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Document your 3 most dreaded tasks, map where information gets lost, automate the repeatable stuff.
Holidays are stressful for CRCs: 'queries don't stop.' Urgency feels productive.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
December 21, 2025 at 3:30 PM
Holidays are stressful for CRCs: 'queries don't stop.' Urgency feels productive.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
But that's not strategy.
Try batching responses, setting sponsor expectations upfront, and automating updates. Protect your time like you protect patient safety. Burning out doesn't help anyone enroll faster.
Protocol amnesia costs you 15 minutes per patient visit.
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
December 20, 2025 at 8:30 PM
Protocol amnesia costs you 15 minutes per patient visit.
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Coordinators flip through protocols mid-visit, hunting visit windows or that one lab requirement.
The best sites? One laminated page per study.
- Visit windows (actual days)
- Critical I/E criteria
- Lab requirements + timing
- CRA contact
Many site coordinators I talk to eat lunch at their desk.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
December 19, 2025 at 7:08 PM
Many site coordinators I talk to eat lunch at their desk.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
You're managing 6 protocols, drowning in source docs, and skipping breaks because "there's too much to do."
Here's the thing: Your research org won't collapse if you leave for 30 minutes. But you might.
Take your break. Leave the building.
Most CRCs spend 15-20 min/visit updating CTMS. That's 6+ hours/week of admin.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
December 18, 2025 at 8:02 PM
Most CRCs spend 15-20 min/visit updating CTMS. That's 6+ hours/week of admin.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.
The trick: spend 90 mins setting up automated visit tracking at protocol launch. Make your calendar the single source of truth.
Result: visits auto-populate, deviations flag themselves. Stop playing detective.