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y-luo.bsky.social
Yang Luo
@y-luo.bsky.social
130 followers 76 following 55 posts
Group Leader @OxfordUni working on MHC, immune-mediated traits, multi-ancestry and omics studies
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · 7d
🌟 Postdoc Opportunity – MRC CoRE in Exposome Immunology 🌟
Join us to explore how the exposome shapes complex disease risk using multi-omics & global biobank data. @kiroxford.bsky.social , @exposomeimmunology.bsky.social

✅ Apply: lnkd.in/gJHJDvKn

🗓️ Deadline: 12pm, 30 Oct 2025
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Reposted by Yang Luo
powrielab.bsky.social
The Powrie Lab @powrielab.bsky.social · 2d
We’re delighted to hear that our favourite cell type (Regulatory T cells!) have been recognised in the Nobel Prize this year! Huge congratulations to Mary, Fred, and Shimon for their pivotal work in the field & here’s to many exciting Treg advances to come!🥳👏🎉
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · 7d
🌟 Postdoc Opportunity – MRC CoRE in Exposome Immunology 🌟
Join us to explore how the exposome shapes complex disease risk using multi-omics & global biobank data. @kiroxford.bsky.social , @exposomeimmunology.bsky.social

✅ Apply: lnkd.in/gJHJDvKn

🗓️ Deadline: 12pm, 30 Oct 2025
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · 13d
@soumya-boston.bsky.social when are you coming ? ;-)
y-luo.bsky.social
Yang Luo @y-luo.bsky.social · 13d
Great to host Fan at Kennedy - explainable AI model in single cell!
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Yang Luo @y-luo.bsky.social · 13d
Great to host Fan at Kennedy - explainable AI model in single cell!
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Reposted by Yang Luo
mrattray.bsky.social
Magnus Rattray @mrattray.bsky.social · Sep 4
We are recruiting two biomedical data scientists as part of a new Centre of Research Excellence (MRC CoRE) in Exposome Immunology hosted jointly by @fbmh-uom.bsky.social and @ox.ac.uk.
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Senior Biomedical Data Scientist:Oxford Road
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
www.jobs.manchester.ac.uk
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · 29d
Congratulations Lino!
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Reposted by Yang Luo
exposomeimmunology.bsky.social
MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 8
WE ARE HIRING! www.manchester.ac.uk/exposome-jobs

Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.

Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.

#hiring #immunosky
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Sep 5
Congratulations Nik!
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Reposted by Yang Luo
kiroxford.bsky.social
Kennedy Institute of Rheumatology @kiroxford.bsky.social · Sep 4
On Monday 8 September, Dr Jonathan Marchini will present 'Using human genetics at scale to power drug discovery'. Our External Seminars are open to any member of the University of Oxford. Don't miss it! talks.ox.ac.uk/talks/id/c42...
A purple and white poster reads 'The Kennedy Institute of Rheumatology external seminar: using human genetics at scale to power drug discovery'. The speaker is Dr Jonathan Marchini from Regeneron Cancer Centre. The seminar will take place on 8 September 2025 in the Kennedy Lecture Theatre - 12:00 to 13:00. It is open to all members of the University of Oxford. It is hosted by Yang Luo.
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Reposted by Yang Luo
kiroxford.bsky.social
Kennedy Institute of Rheumatology @kiroxford.bsky.social · Sep 4
Thinking of applying for a PhD (DPhil) with us?

Join our DPhil Open Day to meet our group leaders and chat with other students!

🗓️ Friday 24 October
⏰ 1 – 5pm
📍 Kennedy Institute

Find out more and register for your place 👉https://www.kennedy.ox.ac.uk/study-with-us/open-day
A blue and white poster reads "Kennedy open day - lab tours, meet our students, taster lectures". It has photos of a lab, a group of students, a building, and a microscopy image. It states a URL as www.kennedy.ox.ac.uk/open-day
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Sep 1
This project is in close collaboration with the amazing @lukejostins.bsky.social, and the student will benefit from a multi-disciplinary team! 🌟🧬🧠
y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Sep 1
🎓 New PhD opportunity in our lab @kiroxford.bsky.social @oxforduni.bsky.social We're exploring host–microbiome genetic interactions in IBD using population-scale data 🧬🦠
🔗 kennedy.ox.ac.uk/.../deciphering-host2013microbiome-genetic-interactions-in-inflammatory-bowel-disease #PhD #Genetics
kennedy.ox.ac.uk
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Sep 1
🎓 New PhD opportunity in our lab @kiroxford.bsky.social @oxforduni.bsky.social We're exploring host–microbiome genetic interactions in IBD using population-scale data 🧬🦠
🔗 kennedy.ox.ac.uk/.../deciphering-host2013microbiome-genetic-interactions-in-inflammatory-bowel-disease #PhD #Genetics
kennedy.ox.ac.uk
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Aug 20
A truly amazing and inspiring PI to work with!
nickywhiffin.bsky.social
Nicky Whiffin @nickywhiffin.bsky.social · Jul 31
📣 We are recruiting! Please share!!

Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺

We have two roles available 👇

🧵 1/4
Image of an old building in Oxford with the heading 'postdoc opportunities' and the text 'computational approaches to improve rare disease diagnosis and treatment' and 'Big Data Institute, University of Oxford'
y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 30
Summer outing for the team — feeling very fortunate to work with such talented and wonderful people.
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Yang Luo @y-luo.bsky.social · Jul 28
Thanks Franze!
y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
Thanks Alex!
y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
Thank you ☺️
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
🙏 Huge thanks to @EstherNg (lab's first postdoc!) for her incredible work, and to @bpfairfax.bsky.social‬ for a fantastic collaboration.
Working with open, brilliant scientists is always a joy — I learned so much about cancer immunology! 😊
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
🔍 As expected, the strongest trans-regulation of TCRs occurs in the MHC region.
What’s interesting 🤨 is that HLA-associated V genes were less stable across treatment. Notably, patients with HLA-regulated TCR clones showed improved overall survival.
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
🧬 In this study, we analysed the genetic regulation of CD8+ TCRs in 250 cancer patients, before and after ICB treatment.
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 28
📣First paper from the lab is out in @science.org‬! 📣https://www.science.org/doi/10.1126/sciadv.adu3461 It’s well known that HLA shapes the TCR repertoire — but how does this change under immune checkpoint blockade (ICB)?
Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade
Immune checkpoint blockade influences the genetically determined relationship between TCR repertoire and HLA alleles in cancer.
www.science.org
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Reposted by Yang Luo
kiroxford.bsky.social
Kennedy Institute of Rheumatology @kiroxford.bsky.social · Jul 25
We're hiring a skilled Research Assistant to process and inventory samples from clinical studies looking at inflammatory diseases, including Rheumatoid Arthritis and Inflammatory Bowel Disease.

Apply by 6 August!

www.kennedy.ox.ac.uk/jobs/researc...
Research Assistant (180619)
As a Research Assistant you'll work across the Coles, Buckley and Dendrou research groups focusing on immune-mediated inflammatory diseases including Rheumatoid Arthritis and Inflammatory Bowel Diseas...
www.kennedy.ox.ac.uk
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Reposted by Yang Luo
lydiabeckeriii.bsky.social
Lydia Becker Institute @lydiabeckeriii.bsky.social · Jul 16
🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases.
#Exposome #ImmunoSky

sites.manchester.ac.uk/lydia-becker...
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A groundbreaking £50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.
sites.manchester.ac.uk
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jul 16
Amazing news! Excited to be part of this new direction of research.
kiroxford.bsky.social
Kennedy Institute of Rheumatology @kiroxford.bsky.social · Jul 16
Huge news! A £50M MRC CoRE will bring together Manchester & Oxford to study how environmental exposures cause chronic inflammatory disease.

The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR.

www.kennedy.ox.ac.uk/news/new-ps5...
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A new Medical Research Council Centre of Research Excellence (MRC CoRE) will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases, such as asthma, ...
www.kennedy.ox.ac.uk
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y-luo.bsky.social
Yang Luo @y-luo.bsky.social · Jun 24
Sarah, a talented master student in the group, is presenting her (4-week-long) work on multi-ancestry HLA-pQTLs at Human Proteome and Health meeting today @ox.ac.uk! 🥳
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