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yaoxiaofang.bsky.social
yaoxiaofang
@yaoxiaofang.bsky.social
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imetascience.bsky.social
💡 An Interpretable Machine Learning Model for Predicting 5-Year Survival in Breast Cancer Based on Integration of Proteomics and Clinical Data! onlinelibrary.wiley.com/doi/10.1002/...
An Interpretable Machine Learning Model for Predicting 5‐Year Survival in Breast Cancer Based on Integration of Proteomics and Clinical Data
This study first introduced Kolmogorov–Arnold Network (KAN) into the deep learning model for the integration of clinical and proteomics data in predicting 5-year survival in breast cancer. The optima...
onlinelibrary.wiley.com
December 26, 2025 at 11:02 AM
Reposted by yaoxiaofang
imetascience.bsky.social
Efficacy and biomarker analysis of neoadjuvant disitamab vedotin (RC48‐ADC) combined immunotherapy in patients with muscle‐invasive bladder cancer
onlinelibrary.wiley.com/doi/10.1002/...
December 30, 2025 at 2:36 AM
Reposted by yaoxiaofang
imetascience.bsky.social
Antioxidants promote metabolic remodeling in cattle rumen epithelium revealed by single‐cell resolution 🐄https://onlinelibrary.wiley.com/doi/10.1002/imt2.70100
Antioxidants promote metabolic remodeling in cattle rumen epithelium revealed by single‐cell resolution
Single-cell and transcriptomics from 1.79 million cells identify the forestomach epithelium as the dominant site of antioxidant activity and oxidative phosphorylation (OXPHOS) in the bovine gastroint...
onlinelibrary.wiley.com
January 5, 2026 at 1:09 PM
Reposted by yaoxiaofang
imetascience.bsky.social
🧪 Nanoplastic exposure disrupts bile acid metabolism and gut microbiota, driving systemic metabolic collapse.
onlinelibrary.wiley.com/doi/10.1002/...
Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction
The pervasiveness of microplastic pollution poses a growing health risk, yet its long-term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanopartic...
onlinelibrary.wiley.com
January 5, 2026 at 1:16 PM
Reposted by yaoxiaofang
imetascience.bsky.social
Tidyplots empowers life scientists with easy code‐based data visualization
onlinelibrary.wiley.com/doi/10.1002/...
January 8, 2026 at 11:56 AM
Reposted by yaoxiaofang
imetascience.bsky.social
A fast, robust readout framework advances large-fragment DNA data storage. onlinelibrary.wiley.com/doi/10.1002/...
Fast bootstrap and reliable readout using hidden references for DNA data storage
This study provides a bootstrap readout framework for DNA data storage based on multiple-fold hidden references. We employ a multi-stage alignment and error correction strategy, transforming the de n...
onlinelibrary.wiley.com
January 12, 2026 at 12:43 PM
Reposted by yaoxiaofang
imetascience.bsky.social
🎯 Engineered bacteria target cancer-associated fibroblasts to break tumor protection!
⚙️ CAT-BLAST, a FAP-targeting E. coli platform, selectively eliminates Cancer-associated fibroblasts and induces tumor cell apoptosis via ClyA secretion.
onlinelibrary.wiley.com/doi/10.1002/...
CAT‐BLAST: Engineered bacteria for robust targeting and elimination of cancer‐associated fibroblasts
Cancer-associated fibroblasts (CAFs) construct a protective stromal barrier that promotes tumor growth and resistance to therapy. To dismantle this, we developed CAT-BLAST, an engineered bacterial pl...
onlinelibrary.wiley.com
January 6, 2026 at 1:10 PM
Reposted by yaoxiaofang
imetascience.bsky.social
Gut microbes help black soldier fly larvae cope with excess uric acid.
⚙️ A uric acid–degrading Enterococcus faecalis strain restores larval growth and improves bioconversion efficiency by catabolizing dietary UA. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
January 7, 2026 at 11:58 AM
Reposted by yaoxiaofang
imetascience.bsky.social
👶 MOMMY study profile: a large prospective birth cohort uncovering early-life microbiome transmission in China.
💡 A unique resource to advance global understanding of early-life microbiome–health trajectories. onlinelibrary.wiley.com/doi/10.1002/...
MOMMY study profile: An integrative early‐life multi‐omics cohort in China
MOMMY cohort (The MOther-infant Microbiota transmission and its link to long terM health of babY) is a large, prospective birth cohort uniquely designed to investigate maternal-paternal-infant microb...
onlinelibrary.wiley.com
January 9, 2026 at 10:54 AM
Reposted by yaoxiaofang
imetascience.bsky.social
🌊A global estuarine virome reveals active virus-carried antibiotic resistance genes.
onlinelibrary.wiley.com/doi/10.1002/...
Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs ...
onlinelibrary.wiley.com
January 14, 2026 at 1:04 PM
Reposted by yaoxiaofang
imetascience.bsky.social
Tidyplots empowers life scientists with easy code‐based data visualization
onlinelibrary.wiley.com/doi/full/10....
#Bioinformatics #R #Rstudio #visualization
Tidyplots empowers life scientists with easy code‐based data visualization
Effective data visualization is vital for analyzing and communicating experimental results. However, most code-based plotting tools require substantial programming experience, posing a significant ba....
onlinelibrary.wiley.com
March 20, 2025 at 8:56 AM