Ultima Genomics AGBT25 updates, with the $80 genome, 25c per million reads and a new Solaris system with higher throughput that runs 50,000 genomes per year. open.substack.com/pub/albertvi...
Ultima Genomics AGBT25 updates
What does it mean for the NGS short-reads race with Illumina and Roche SBX?
open.substack.com
March 10, 2025 at 5:11 PM
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Bruker NanoString AGBT25 open.substack.com/pub/albertvi...
Bruker NanoString AGBT25
Technically competitive, but will they get any commercial traction?
open.substack.com
March 10, 2025 at 8:45 AM
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#AGBT25 Ultima Workshop Video is available on-demand www.ultimagenomics.com/resources/?c...
Resources | Ultima Genomics
www.ultimagenomics.com
March 4, 2025 at 6:04 PM
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🚀 Exciting news from #EASIGEN-DS team!
Last week, Ivo Gut and Tuuli Lappalainen @tuuliel.bsky.social, members of #EASIGEN-DS, attended the prestigious #AGBT25 meeting in 📍Marco Island, Florida.
If you want to know more – check out the post below!
#Genomics #EASIGEN #Innovation #Research
Last week, Ivo Gut and Tuuli Lappalainen @tuuliel.bsky.social, members of #EASIGEN-DS, attended the prestigious #AGBT25 meeting in 📍Marco Island, Florida.
If you want to know more – check out the post below!
#Genomics #EASIGEN #Innovation #Research
EASIGEN on LinkedIn: #easigen #easigen #agbt25 #agbt25 #genomics #easigen #innovation #research
🚀 Exciting news from #EASIGEN-DS team!
Last week, Ivo Gut and Tuuli Lappalainen, members of the #EASIGEN-DS team, attended the prestigious #AGBT25 meeting…
www.linkedin.com
March 3, 2025 at 11:10 AM
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This is from the Illumina #AGBT25 workshop about their ST tech.
But, from our observations, under heavy lateral diffusion (real or simulated), clustering on large sets of genes (i.e. “whole transcriptome”) leads to niche- rather than cell-type clustering.
This might be problematic.
But, from our observations, under heavy lateral diffusion (real or simulated), clustering on large sets of genes (i.e. “whole transcriptome”) leads to niche- rather than cell-type clustering.
This might be problematic.
March 1, 2025 at 5:59 PM
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Waiting for my flight so I have time to reflect on the past week #agbt25
February 28, 2025 at 8:32 PM
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My top-THREE non-Roche-SBX #AGBT25 takeaways:
1. Spatial Genomics is the new shiny object
2. Methylation detection was ubiquitous and varied
3. Normalization of libraries improved but was iterative
If you're looking for Bioinformatics help, give me a call!
1. Spatial Genomics is the new shiny object
2. Methylation detection was ubiquitous and varied
3. Normalization of libraries improved but was iterative
If you're looking for Bioinformatics help, give me a call!
February 28, 2025 at 8:21 PM
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Illumina AGBT25 update. Positive progress on innovation, but everything new is 18 months away. open.substack.com/pub/albertvi... #NGS #NextGenSequencing #Multiomics
Illumina AGBT25 update
Positive progress on innovation, but everything is 18 months away.
open.substack.com
February 28, 2025 at 8:59 AM
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A reminder that the illumina spatial solution might be second half 2026. #AGBT25 #Spatial #multiomics #NGS
February 28, 2025 at 5:29 AM
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One big npn-announcement from Illumina $ILMN at #AGBT25 is that they could come up with a nanopore method in 2030. Oxford @nanoporetech.com is available today.
February 27, 2025 at 4:00 PM
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February 27, 2025 at 3:54 PM
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The sun is setting on #AGBT25. But that doesn't mean the action has to stop. We invite intrepid researchers everywhere to keep up with us at our website below!
Mastering Biology to Advance Human Health - 10x Genomics
We deliver powerful, reliable tools that fuel scientific discoveries and drive exponential progress to master biology to advance human health.
www.10xgenomics.com
February 26, 2025 at 10:02 PM
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#AGBTGM #AGBT2025 #AGBT25 AP: quoll may go extinct in next 10 yrs. Eats toads but introduced cane toad is toxic and kills quoll. Toxin impacts ATP1A1 gene- should be able to introduce resistance. 1 single bp change increased resistance 6000x. Will help reduce spread of cane toads.
February 26, 2025 at 7:57 PM
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February 26, 2025 at 7:50 PM
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#AGBTGM #AGBT2025 #AGBT25 AP: Have worked on other marsupial genomes. Find closest living relative to extinct animal. About 500K edits relative to dunnart. Even though dunnart is tiny relative to thylacine, both are marsupials so have tiny babies and can maybe serve as surrogate.
February 26, 2025 at 7:46 PM
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#AGBTGM #AGBT2025 #AGBT25 AP: role of animals in landscape shown by removing and reintroducing wolf in Yellowstone. Exceptional genome resources for thylacine. Have baby preserved in alcohol. Also found mother in alcohol. Have gotten long DNA from teeth. Have 9x long read sequence, 18 gaps remain.
February 26, 2025 at 7:43 PM
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#AGBTGM #AGBT2025 #AGBT25 AP: tool kit for de-extinction - T2T genomes, gene editing, ART, stem cells, biobanking. Thylacine became extinct in 1936, apex predator so led to ecosystem destabilization. Impact on tasmanian devil because sick individuals are not removed leading to spread of tumors
February 26, 2025 at 7:37 PM
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#AGBTGM #AGBT2025 #AGBT25 JD: Try to assemble genome. 3.5M PacBio reads., 26M Illumina reads. Growth of trophozoites inhibited by nitroxoline but restored by Fe or Cu supplementation. CDC guidelines have been changed to nitroxoline and stock held for use as needed
February 26, 2025 at 7:30 PM
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#AGBTGM #AGBT2025 #AGBT25 JD: Repurposing screen of 2017 drugs identify nitroxline to kill trophozoites. Not approved in US. Used for UIs. New patient identified several years later. Emergency IND to give nitroxoline. Saw near full recovery and still surviving 3 yrs later.
February 26, 2025 at 7:23 PM
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