Excited to share our new study using metagenomes to reveal key players in 2,6-Diaminopurine (dZ) Biosynthesis : We explore how some bacteriophages swap dA for 2-aminoadenine (dZ) in their genomes to evade bacterial defenses. #PhageBiology #Metagenomics #bacteriophage www.biorxiv.org/content/10.1...
October 24, 2025 at 12:56 PM
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👀 Check out these new CFRI podcast recordings from the CF Adult Summer Retreat! Each session dives into critical topics impacting the #cysticfibrosis community.
curecf.cfri.org/ResistantInf...
curecf.cfri.org/GutMicrobiome
curecf.cfri.org/Bacteriophages
curecf.cfri.org/Vaccines
curecf.cfri.org/ResistantInf...
curecf.cfri.org/GutMicrobiome
curecf.cfri.org/Bacteriophages
curecf.cfri.org/Vaccines
October 24, 2025 at 1:52 AM
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We live in the decade of generative models and biology is no exception.
Genome language models can now generate functional bacteriophages!
Read more in my new sub-stack post where I explore the @arcinstitute.org latest pre-print.
Genome language models can now generate functional bacteriophages!
Read more in my new sub-stack post where I explore the @arcinstitute.org latest pre-print.
October 22, 2025 at 6:29 PM
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Today we welcomed @nataliegreenpeer.bsky.social to the Quadram Institute to learn more about our food, gut microbiome and health research including hearing from our experts about our work on bacteriophages
Find out more about our research targets
➡️ buff.ly/STa42fW
Find out more about our research targets
➡️ buff.ly/STa42fW
October 15, 2025 at 3:00 PM
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Looking forward to this inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics,
Starting tomorrow.
www.iasusa.org/bacteriophag...
#phage #phagesky
Starting tomorrow.
www.iasusa.org/bacteriophag...
#phage #phagesky
Conference on Bacteriophages: Biology, Dynamics, and Therapeutics - IAS-USA
Physical Education: Bridging Clinical Research and Patient Care
www.iasusa.org
October 12, 2025 at 3:04 AM
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Don't ask Claude Sonnet 4.5 about this paper:
www.biorxiv.org/content/10.1...
It's about using genome language models to create new bacteriophages and I swear to god it triggers an ASL-3 chat lockdown.
www.biorxiv.org/content/10.1...
It's about using genome language models to create new bacteriophages and I swear to god it triggers an ASL-3 chat lockdown.
October 5, 2025 at 4:44 PM
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Viruses number in the trillions yet remain relatively obscure. But what we’re learning about one group of viruses that target bacteria, called bacteriophages, may shape the future of medicine. This week, it’s “Not Just a Phage” on @bipisci.bsky.social 🧪
Listen here: buff.ly/hsmEy4S
Listen here: buff.ly/hsmEy4S
October 3, 2025 at 11:01 PM
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Day 3, Soft. Soft agar is used to visualise phages - plaque assay: bacteria infected with phages are mixed with soft agar, poured over an agar plate. A bacterial lawn grows & plaques appear - as phages infect bacteria, multiply, kill & repeat to form an expanding hole. #drawtober #SciArt #Phagesky
October 3, 2025 at 4:14 PM
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Could viruses be the good guys? An obscure 100-year-old medical therapy to treat infection enlists viruses called bacteriophages that evolved to target bacteria. Can it help us avoid a post-antibiotic world? This week, it’s “Not Just a Phage” on @bipisci.bsky.social 🧪
Listen here: buff.ly/hsmEy4S
Listen here: buff.ly/hsmEy4S
September 29, 2025 at 7:01 PM
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“Paraxenoviridae”, a putative family of globally distributed marine bacteriophages with double-stranded RNA genomes
#viruses #bacteriophages #phages
@isme-microbes.bsky.social
academic.oup.com/ismej/articl...
#viruses #bacteriophages #phages
@isme-microbes.bsky.social
academic.oup.com/ismej/articl...
“Paraxenoviridae”, a putative family of globally distributed marine bacteriophages with double-stranded RNA genomes
Abstract. Metatranscriptome sequencing dramatically expanded the known diversity of the global RNA virome and, in particular, suggested several new candida
academic.oup.com
September 28, 2025 at 7:57 AM
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A new technique using modified bacteriophages enables precise identification of highly selective peptides, offering potential for improved diagnostics and targeted therapies in cancer and diabetes. doi.org/g942q5
Modified bacteriophages help pinpoint peptides with therapeutic potential
An international study led by researchers from the Department of Medicine and Life Sciences (MELIS) of Pompeu Fabra University and Stanford University (California) has designed a system to identify highly selective peptides with high therapeutic potential.
phys.org
September 25, 2025 at 6:24 PM
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Many thanks to @mikrobiokosmos.bsky.social for the opportunity to present the results of my research on the genomic and ecological characterization of novel cultivated bacteriophages infecting
abundant bacterial freshwater lineages.
@isme-microbes.bsky.social #phage #mbkceesmes
abundant bacterial freshwater lineages.
@isme-microbes.bsky.social #phage #mbkceesmes
September 24, 2025 at 7:16 AM
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Here footage of a game Im making about bacteriophages that have been cybernetically enhanced to be able to handle weapons and kill bacteria
Also, I need an artist thats better than me by quite a large margin
#gamedev #newgamedev #game #artistneeded
Also, I need an artist thats better than me by quite a large margin
#gamedev #newgamedev #game #artistneeded
September 23, 2025 at 3:56 PM
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🦠 AI designs viruses for the first time
Scientists used AI to generate complete viral genomes, creating bacteriophages that killed antibiotic-resistant E. coli. A step toward AI-designed life, with big ethical questions.
🔗 doi.org/10.1038/d415...
#SciComm #SyntheticBiology 🧪 #GenAI #AI
Scientists used AI to generate complete viral genomes, creating bacteriophages that killed antibiotic-resistant E. coli. A step toward AI-designed life, with big ethical questions.
🔗 doi.org/10.1038/d415...
#SciComm #SyntheticBiology 🧪 #GenAI #AI
World’s first AI-designed viruses a step towards AI-generated life
Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.
doi.org
September 22, 2025 at 8:02 PM
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Incredibly proud of Dr Revathy who is inspiring the next generation of scientists around the world. And even though we can't see them through a foldscope, bacteriophages are still our favourite microbes 🤩
quadram.ac.uk/blogs/inspir...
quadram.ac.uk/blogs/inspir...
Inspiring the next generation: exploring the invisible microbial world with students in Koothanoor, India - Quadram Institute
Research Scientist Dr Revathy Krishnamurthy reflects on her visit to the village where she grew up in India and inspiring the next generation to discover the world of science.
quadram.ac.uk
September 22, 2025 at 10:41 AM
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世界で初めてAIでウイルスのゲノムを設計することに成功
https://gigazine.net/news/20250922-generative-ai-design-bacteriophages-genome/
https://gigazine.net/news/20250922-generative-ai-design-bacteriophages-genome/
世界で初めてAIでウイルスのゲノムを設計することに成功
by Applied Microbiology International
gigazine.net
September 22, 2025 at 3:00 AM
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The group in #brianhie.bsky.social at Stanford used AI to design the first-ever functional bacteriophages. AI can explore countless phage genomes in silico, speeding discovery of new alternatives to antibiotics. A breakthrough for #AMR, but also raises ethical & safety questions. #AI #Biotech
In a new preprint from @brianhie.bsky.social's lab, the team reports the first generative design of viable bacteriophage genomes.
Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.
Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.
September 22, 2025 at 4:03 AM
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Sunday evening Timeline cleanse: des trop p’tits choubidoux bactériophages en train d’attaquer une bactérie 🤩
September 21, 2025 at 6:58 PM
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The Radio 4 “In our time” archive is a goldmine and the range is astounding. In the last week or so I’ve listened to the Industrial Revolution (x 2), Typology, Pope Joan and Bacteriophages
www.bbc.co.uk/programmes/b...
www.bbc.co.uk/programmes/b...
BBC Radio 4 - In Our Time
Melvyn Bragg and guests discuss the ideas, people and events that have shaped our world.
www.bbc.co.uk
September 20, 2025 at 12:19 PM
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I saw Pope Joan and the Bacteriophages before their first hit album
September 20, 2025 at 12:21 PM
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"Stanford bioengineers claim they've created synthetic bacteriophages using AI-generated designs that not only work in the real world, but are far more infectious than their naturally-occurring counterparts"
Are you ready to regulate AI yet?
#Virus #Pandemic #WMD #C4News
bsky.app/profile/ther...
Are you ready to regulate AI yet?
#Virus #Pandemic #WMD #C4News
bsky.app/profile/ther...
AI can now design functional viruses - not the computer kind, either
AI can now design functional viruses - not the computer kind, either
Inject this synthetic phage into E. coli and it kills better than the real thing
A group of Stanford bioengineers claim that they've created synthetic bacteriophages using AI-generated designs that not only work in the real world, but are far more infectious than their naturally-occurring counterparts. …
dlvr.it
September 18, 2025 at 5:08 PM
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Earlier this year, Professor Chloe E James, a member of our KO AMR Scientific Advisory group, was involved in several events at the House of Lords that brought together global experts to discuss bacteriophages as a vital tool against AMR. Check out her blog: microb.io/3KbjdhT
September 18, 2025 at 8:46 AM
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Genome language models can generate new, high-fitness bacteriophages!
@samuelhking.bsky.social @claudiadriscoll.bsky.social
@david-li.bsky.social @danguo.bsky.social @adititm.bsky.social Garyk Brixi @maxewilkinson.bsky.social @brianhie.bsky.social
www.biorxiv.org/content/10.1...
@samuelhking.bsky.social @claudiadriscoll.bsky.social
@david-li.bsky.social @danguo.bsky.social @adititm.bsky.social Garyk Brixi @maxewilkinson.bsky.social @brianhie.bsky.social
www.biorxiv.org/content/10.1...
September 17, 2025 at 9:15 PM
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Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
September 17, 2025 at 3:03 PM
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Don’t miss the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, October 12–14, 2025, in Washington, DC. A 2.5-day program of invited talks, symposia, workshops, and abstracts will highlight the latest advances. For more info: bit.ly/3JUKLYL
Conference on Bacteriophages: Biology, Dynamics, and Therapeutics - IAS-USA
Physical Education: Bridging Clinical Research and Patient Care
bit.ly
September 11, 2025 at 1:11 PM
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