On Ashwin 23, 2082, CDSC signed an important agreement with Sagar Distillery Limited and Muktinath Capital Limited. The deal focuses on the dematerialization

Sagar Distillery Limited has published the result of its Initial Public Offering (IPO) issued for Nepalis working abroad.

CDS and Clearing Limited (CDSC), a government-owned company, has issued a new notice to all listed companies, share registrars, and transfer agents.

CDSC group retreat at Purdue, 2024 Thinking about applying to graduate school? Wonder what it’s like to pursue a PhD? Interested in understanding relationships between technology and society? Curio…

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The Corynebacterium (C.) diphtheriae species complex (CdSC) comprises the closely related pathogenic species C. diphtheriae, C. belfantii, C. rouxii, C. ulcerans, C. silvaticum, C. ramonii and C. pseudotuberculosis according to the taxonomic revisions after 2018. Due to their close relationship, reliable species identification within the CdSC is also challenging using MALDI-TOF mass spectrometry (MS) for fast and reliable identification of bacteria. However, the most commonly used commercial databases for MALDI-TOF MS do not reflect the current CdSC taxonomy. Therefore, the objective of the present study is to expand the Bruker MALDI-Biotyper database version K (MBTK) in order to achieve reliable identification for all currently known Corynebacterium species within the CdSC. Furthermore, the database extensions were verified with a systematic formal validation procedure in accordance with the German guideline for species identification by MALDI-TOF MS. For this, 321 strains including all seven valid species of the CdSC were identified with a set of 328 spectra using the commercial MBTK database and a customer-supplemented modified MBTK. This custom database version included 33 reference spectra of the CdSC and representatives of all four recently described species. The results of the formal validations for both, the commercial and the extended database, combined partly with a single signal analysis, provide a substantiated basis for the identification of bacteria of the CdSC. A key element for a fast up-to-date identification has been the exchange of user-generated sets of MSPs on the open access MALDI-UP catalogue that includes reference spectra for all members of the CdSC.

The Nepal Stock Exchange (NEPSE) has suspended Broker No. 20, Sipla Securities Pvt. Ltd., for a period of three trading days starting from Asar 23.

Thinking about applying to graduate school? Wonder what it’s like to pursue a PhD or M.S.? Interested in understanding relationships between technology and society? Curious about how to do research…

NAIROBI, Kenya, April 15 – The Central Depository and Settlement Corporation (CDSC) has announced its decision to unsubscribe from the Rhino chatbot service, with the termination set to take effect on April 18, 2025. In a communication sent to users, Team Rhino confirmed that CDSC’s chatbot services would be decommissioned, meaning clients will no longer […]