#CircAHA
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haoyin.bsky.social
Histone Variants
#SmoothMuscleCell

1⃣H2A.Z
⬇️in #Atherosclerosis
⏫SMC contractile gene
#CircAHA 2018
www.ahajournals.org/doi/10.1161/...
#BMCGenom 2025
bmcgenomics.biomedcentral.com/articles/10....

2⃣H3.3B
⬆️in #AorticDissection
⏫SMC synthetic genes
#Genomics 2023
www.sciencedirect.com/science/arti...
October 15, 2025 at 9:16 PM
friendsofgri.bsky.social
Some nice news to share with you 😍 #griref="/hashtag/gri" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#gri is now included in @CircAHA Hospitals of History 🤩☺️ #gri in print! Read the short article here 👉🏻 https://bit.ly/3e2wGqj Thanks @drpaddymark for the tag ⭐️👏🏻
November 17, 2024 at 5:49 AM
kristalentine.bsky.social
Thanks to @CircAHA for publishing our new @American_Heart #ScientificStatement on ‘#Cardiorenal Syndrome (CRS).’ Mapping current classification, pathophysiology, #diagnosis & #treatment outlines a path to improving science & #PatientCare. @RangaswJ @McCulloughBHVH @SLUHealthNews
November 28, 2024 at 8:15 AM
victorchanginst.bsky.social
1st individual gene mutation test for predicting risk of sudden cardiac death has been developed by Prof @VandenbergJamie + Dr @ChaiAnn_Ng. The collaborative research in @CircAHA will make a huge difference in how high-risk Long QT patients are cared for:

smh.com.au/national/what-…
What are the chances of your heart suddenly stopping? Scientists think they can tell
Jess Berenyi only discovered her heart condition when it nearly killed her. A new database will help others discover their genetic risk before it’s too late.
www.smh.com.au
January 29, 2025 at 3:16 AM
justequity.bsky.social
A new report released by @American_Heart reviews the latest statistics on heart disease, stroke, and cardiovascular risk factors with a focus on health equity to address structural racism in medicine.

Read more from @CircAHA: https://buff.ly/3SxJyrc
November 16, 2024 at 9:01 PM
thaiscoutinho.bsky.social
6/ For more details, read the open-access paper, and listen to our interview on the Circulation on the Run podcast! 👉🏻 bit.ly/4hGJpNf Congrats to @amydjohn , @brainheartnexus @MaternalHC and all our coauthors ; and big THANKS to @CircAHA for highlighting our work!
Circulation on the Run Go Red for Women Issue: February 18, 2025 | AHA Podcasts
bit.ly
February 19, 2025 at 3:00 AM
tonybreu.bsky.social
@CircAHA 2/
Patient One had chronic anemia with a hemoglobin 1.5 g/dL. You'll see that before receiving blood they had the following cardiac parameter:

• HR 100 (elevated)
• Cardiac index 8.9 (elevated)
• Stroke index 89 (elevated)
November 16, 2024 at 2:11 PM
gudnephron.bsky.social
Our ⭐️ chief fellow @nephrozac Isaac Kim presents journal club on Kidney GDMT
Discusses @brendonneuen article and concept of the 4 pillars of Kidney GDMT

@UCKidney
@UCincyMedicine
@UCincyIM
@uofcincy
@CircAHA

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.067584
December 11, 2024 at 6:33 PM
victorchang.edu.au
533 genetic variants associated with Long QT have been analysed in @CircAHA study using a high-throughput APC assay. Some variants reduce function of ion channel by up to 90% resulting in a 13.3x risk of major cardiac events:@VandenbergJamie @ChaiAnn_Ng

victorchang.edu.au/news/test-risk…
World's First Test for Predicting Risk of Sudden Cardiac Death - Victor Chang Cardiac Research Institute
Institute scientists develop a world-first individualised risk prediction tool for people suffering from a type of arrhythmia that can cause sudden cardiac arrest.
www.victorchang.edu.au
December 10, 2024 at 4:06 AM
katherine-maki1.bsky.social
Join Editors of @CircAHA, @CircRes, and @JAHA_AHA and learn more about the publication process. #AHA24

Publishing Without Perishing: A Discussion With Leading Journal Editors

Friday, Nov 15 @ 3-4pm CT

Room: S105ABC

Program link: eppro01.ativ.me/appinfo.php?...
AHA24
eppro01.ativ.me
November 15, 2024 at 5:04 PM
natcardiovascres.nature.com
We highlight the study by Marcus et al. in @CircAHA, where the authors showed that a transseptal approach to catheter ablation can maintain the procedure’s anti-arrhythmic benefits while reducing brain damage.

👉https://rdcu.be/egl4s
April 4, 2025 at 10:32 AM
aagarwalamd.bsky.social
#CVprev risk assessment in women is incomplete without a comprehensive assessment of sex- specific risk factors! @CircAHA #GOREDFORWOMEN #Cardioobstetrics @virani_md @ErinMichos @CBallantyneMD @ZainabASamad @AKUGlobal @BCMHeart @WUSTLmed @CiccaroneCenter

ahajournals.org/doi/abs/10.116…
November 30, 2024 at 4:14 AM
tonybreu.bsky.social
@CircAHA 3/
After transfusion to a hemoglobin of 10 g/dL, the following changes were noted:

• HR 100 (elevated but unchanged)
• Cardiac index 3.4 (decreased and now normal)
• Stroke index 34 (decreased and now normal)
November 16, 2024 at 2:20 PM
ahajournals.bsky.social
A new collaboration between the New England Journal of Medicine (NEJM) & the American Heart Association's flagship journal Circulation was just announced. Starting in early 2025, research authors can select a seamless transfer of their manuscript between @NEJM & @CircAHA #AHA24
November 17, 2024 at 9:15 PM
victorchang.edu.au
New @CircAHA paper by Prof Richard Harvey and Dr Vaibhao Janbandhu describes a novel mouse strain marking myofibroblasts, the main driver of cardiac fibrosis. It represents a step forward in classifying and manipulating myofibroblasts:

doi.org/10.1161/CIRCUL…
Novel Mouse Model for Selective Tagging, Purification, and Manipulation of Cardiac Myofibroblasts | Circulation
eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.
doi.org
January 29, 2025 at 4:40 AM
haoyin.bsky.social
Lung #EndothelialCell Plasticity

Arterialization of General capillary EC in #PulmonaryHypertension
👤#iPAH
🐭Tie2-Cre::PHD2 f/f
🐭Sugen5416+Hypoxia

scRNAseq
#SpatialTranscriptomics Visium
A novel Plvap-DreERT2 gCapEC lineage reporter 🐭
Cool😎

#CircAHA 2024
www.ahajournals.org/doi/10.1161/...
July 31, 2024 at 4:30 PM
hvanspall.bsky.social
#GlobalRounds
@CircAHA
@AHAjournals.bsky.social

#Afghanistan faces a #health crisis: low life expectancy, few cardiologists, high #CVD ☠️ & political/economic forces that disproportionately impact women

Read about challenges our Afghan colleagues face
https://www.ahajournals.org/doi/10.1161/CIRCU…
January 21, 2025 at 11:13 PM
drwanpen.bsky.social
Delighted to share perspective piece @CircAHA on history of resistant HTN with @adinaturcu.bsky.social. In the US, it was 1st defined by JNC V report. Back then, RH need combination of diuretic+2 drugs: BB, vasodilator, CCB, or ACEI. We have come a long way! #Cardiosky #Nephsky
tinyurl.com/3tttvaye
The Journey of Resistant Hypertension: From the Fifth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure to American Heart Association/American Colle...
tinyurl.com
March 10, 2025 at 8:43 PM
haoyin.bsky.social
#CRISPR #RNAEditing #HypertrophicCardioMyopathy

AAV9-hpCas13d/gRNA
⏬30% RQ mutant mRNA
Partially rescue cardiac hypercontractility, LV hypertrophy & cardiomyocyte loss in early onset HCM of 2-mo Myh6 p.R872H/p.R404Q🐭

Resolve multiple🧍MYH7 variants

#CircAHA 2024
www.ahajournals.org/doi/10.1161/...
April 1, 2025 at 12:01 PM
haoyin.bsky.social
Activating #HexosamineBiosynthesisPathway to treat #PeripheralArteryDisease

Glucosamine i.p. ⏫Reperfusion #Angiogenesis but not #Arteriogenesis in🐭#LimbIschemia (BALB/c, eNOS-/- C57BL/6)

Distinct pathways from VEGFA

ATF4 as a signaling mediator

#CircAHA 2024
www.ahajournals.org/doi/10.1161/...
November 14, 2024 at 1:04 PM
ernestob.bsky.social
Resultados de Ensayo Clínico para evaluar Screening de Fibrilación Auricular con Kardia AliveCor®→App para realizar EKG en teléfono móvil https://twitter.com/CircAHA/status/902425703240671232
November 18, 2024 at 2:06 PM
victorchang.edu.au
533 genetic variants associated with Long QT have been analysed in @CircAHA study using a high-throughput APC assay. Some variants reduce function of ion channel by up to 90% resulting in a 13.3x risk of major cardiac events:@VandenbergJamie @ChaiAnn_Ng

victorchang.edu.au/news/test-risk…
World's First Test for Predicting Risk of Sudden Cardiac Death - Victor Chang Cardiac Research Institute
Institute scientists develop a world-first individualised risk prediction tool for people suffering from a type of arrhythmia that can cause sudden cardiac arrest.
www.victorchang.edu.au
January 29, 2025 at 4:50 AM
hadleymd.bsky.social
🤔 Thought-provoking piece in @CircAHA from Kole & Joshi

🫀 A growing group of patients with subclinical atherosclerosis falls in between traditional "primary" and "secondary" prevention. I've heard of "prevention 1.5" or "plaque-informed prevention." How about the following classification system?👇
October 27, 2025 at 10:21 PM
ahajournals.bsky.social
Journal Session @ #AHA25

EHJ and Circulation: Advances in 2025
Featuring Dr. Joseph A. Hill, Dr. Maryjane Farr, and other @CircAHA editors

Saturday 11/8 @ 1:30-2:45pm
Room 210

Add to your schedule: https://ahajrnls.org/43ihSN5
November 7, 2025 at 10:25 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @nejm.org and #CircAHA

https://www.ahajournals.org/circ/nejm-circulation-collaboration

#TCT2025
October 25, 2025 at 9:00 PM