#GeneCircuits
🚨Job alert!
🔬We have 2 new open positions (1 PhD, 1 postdoc) in our team (santosmorenolab.org) in Barcelona @upf.edu @prbb.org funded by @erc.europa.eu
If you are passionate about #SynBio and #GeneCircuits, apply now! (until Oct. 26th) 🦠🔧
Info below 👇Please RT!
October 9, 2025 at 2:35 PM
Recent research shows evolution reshapes gene circuits, allowing new patterns like stripes and spots, and swapping regulatory elements between species can reproduce donor traits. https://getnews.me/how-evolution-rewires-gene-circuits-to-create-new-biological-patterns/ #evolution #genecircuits
September 16, 2025 at 5:21 PM
A recent paper explores this by engineering gene circuits with adaptive behaviors. Check out https://www.nature.com/articles/s41587-023-01756-8 for more insights into autonomous synthetic gene circuits. #SyntheticBiology #GeneCircuits
August 13, 2025 at 7:16 PM
Great talk by @jamespblloyd.bsky.social today using Recombinases to produce #GeneCircuits for #Plants. Lots of interesting potential uses for #Biotech and fundamental #Science! Covered lots of info from his paper: rdcu.be/dSuHu
Synthetic memory circuits for stable cell reprogramming in plants
Nature Biotechnology - Transcriptional activity in plants is controlled with a programmable gene circuit.
rdcu.be
August 30, 2024 at 3:48 PM
🚨We have a fully funded open PhD position in bacterial synthetic biology available in our lab (www.yschaerli.com) in beautiful Lausanne, Switzerland @dmf-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social
If you are passionate about #SynBio and #GeneCircuits, apply here: tinyurl.com/mry2xwa5
April 9, 2025 at 8:22 AM
On #WorldCancerDay, we acknowledge the stories behind every cancer diagnosis—resilience, loss, hope, and healing. These stories drive us to develop intelligent #GeneCircuits for next-gen cell and #genetherapies, aiming to transform outcomes for cancer patients. #UnitedByUnique
February 4, 2025 at 1:59 PM
🆕 Another preprint!
CRISPRi-linked multi-module negative feedback loops to combat winner-take-all dynamics from resource competition in gene circuits.
📄 www.biorxiv.org/content/10.1...
#SynBio #CRISPRi #GeneCircuits #ResourceCompetition
CRISPRi-Linked Multi-Module Negative Feedback Loops to Address Winner-Take-All Resource Competition
Cellular resource limitations create unintended interactions among synthetic gene circuit modules, compromising circuit modularity. This challenge is particularly pronounced in circuits with positive ...
www.biorxiv.org
May 18, 2025 at 4:28 AM
One promising study is "Principles of genetic circuit design" by Brophy and Voigt, which explores how to engineer gene circuits that emulate natural functions. Read more at https://www.nature.com/articles/nmeth.2926 #SyntheticBiology #GeneCircuits
September 15, 2025 at 5:59 PM
🚨 New preprint!
We present Re-NF-FF-Controller—a compact strategy that integrates negative feedback and feedforward control via a single promoter flip to optimally decouple resource competition.
📄 www.biorxiv.org/content/10.1...
#SynBio #GeneCircuits #ResourceCompetition
Integrating Recombinase-Based Feedback and Feedforward Control for Optimal Resource Decoupling
Resource competition disrupts circuit modularity by introducing unintended coupling between otherwise independent gene modules, thereby compromising genetic circuit function. While various control str...
www.biorxiv.org
May 16, 2025 at 7:55 PM
#SyntheticBiology #GeneCircuits
May 26, 2025 at 3:27 PM