Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas)#glycotimee#GlycoconjugateJournall
Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas)
Norovirus (NoV), an important cause of human viral gastroenteritis worldwide, recognizes human histo-blood group antigens (HBGAs) as receptors. Oysters are
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October 1, 2025 at 4:45 PM
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Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation#glycotimee#GlycoconjugateJournall
Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation
The advanced glycation end-product Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) accumulates during the progress of atherosclerosis with type 2 diabe
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October 1, 2025 at 4:45 PM
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Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights
#glycotime #GlycoconjugateJournal
#glycotime #GlycoconjugateJournal
Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights
Diabetes mellitus (DM) is marked by prolonged elevated blood glucose levels, which lead to the formation of covalent adducts between glucose and plasma pro
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September 22, 2025 at 4:45 PM
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Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells
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#glycotime #GlycoconjugateJournal
Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells
Cystic Fibrosis (CF), a life-threatening hereditary disease, arises from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene,
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July 15, 2025 at 4:45 PM
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Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species
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#glycotime #GlycoconjugateJournal
Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species
Gram-positive bacterial biomembranes are composed of phosphatidyl glycerol (PG), cardiolipin (CL), and dihexaosyl diglycerides (DH-DG) as the major lipid c
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July 15, 2025 at 4:45 PM
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Analysis of site-dependent mucins in rat intestinal mucosa using anti-glycan monoclonal antibodies
#glycotime #GlycoconjugateJournal
#glycotime #GlycoconjugateJournal
Analysis of site-dependent mucins in rat intestinal mucosa using anti-glycan monoclonal antibodies
Intestinal gel-forming mucins are high-molecular weight glycoproteins, and their glycan moieties vary depending on the intestinal site. Although the means
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June 28, 2025 at 4:45 PM
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Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments
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#glycotime #GlycoconjugateJournal
Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments
Trypanosoma brucei (T. brucei) parasites cause two major infectious diseases in Africa: African trypanosomiasis in humans (HAT) and Nagana in animals. Desp
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June 24, 2025 at 4:45 PM
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Lectin-glycan interactions: a comprehensive cataloguing of cancer-associated glycans for biorecognition and bio-alteration: a review
#glycotime #GlycoconjugateJournal
#glycotime #GlycoconjugateJournal
Lectin-glycan interactions: a comprehensive cataloguing of cancer-associated glycans for biorecognition and bio-alteration: a review
This comprehensive review meticulously compiles data on an array of lectins and their interactions with different cancer types through specific glycans. Cr
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June 5, 2025 at 4:45 PM
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GM1 oligosaccharide-mediated rescue in GBA-linked Parkinson’s disease via modulation of lysosomal and mitochondrial dysfunction#glycotimem#GlycoconjugateJournalal
GM1 oligosaccharide-mediated rescue in GBA-linked Parkinson’s disease via modulation of lysosomal and mitochondrial dysfunctions
Mutations in the glucocerebrosidase GBA gene, encoding the lysosomal enzyme β-glucocerebrosidase, represent the most frequent genetic risk factor for
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June 4, 2025 at 4:45 PM
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Anti-GalNAcα (anti-Tn) antibody repertoire differs between individuals with blood groups A and B#glycotimee#GlycoconjugateJournall
Anti-GalNAcα (anti-Tn) antibody repertoire differs between individuals with blood groups A and B
Recently, Breiman et al. (2021) reported that the level of anti-Tn in the blood of healthy donors and COVID-19 patients is significantly lower in individua
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April 26, 2025 at 4:45 PM
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Limited support for a direct connection between prebiotics and intestinal permeability – a systematic revie#glycotimem#GlycoconjugateJournalal
Limited support for a direct connection between prebiotics and intestinal permeability – a systematic review
The intestinal barrier is a selective interface between the body´s external and the internal environment. Its layer of epithelial cells is joined toge
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March 26, 2025 at 3:50 PM
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Association between O-GlcNAc levels and platelet function in obese insulin-resistant subjects
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#glycotime #GlycoconjugateJournal
Association between O-GlcNAc levels and platelet function in obese insulin-resistant subjects
Obesity is an epidemic associated with platelet and vascular disorders. Platelet O-GlcNAcylation has been poorly studied in obese subjects. We aimed to eva
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March 26, 2025 at 3:50 PM
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Site-directed mutagenesis leads to the optimized transglycosylation activity of endo-beta-N-acetylglucosaminidase from Trypanosoma brucei
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#glycotime #GlycoconjugateJournal
Site-directed mutagenesis leads to the optimized transglycosylation activity of endo-beta-N-acetylglucosaminidase from Trypanosoma brucei
Endo-β-N-acetylglucosaminidases (ENGases) are pivotal enzymes in the degradation and remodeling of glycoproteins, which catalyze the cleavage or forma
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March 26, 2025 at 3:49 PM
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RACK1 inhibits ferroptosis of cervical cancer by enhancing SLC7A11 core-fucosylation
#glycotime #GlycoconjugateJournal
#glycotime #GlycoconjugateJournal
RACK1 inhibits ferroptosis of cervical cancer by enhancing SLC7A11 core-fucosylation
Receiver for Activated C Kinase 1 (RACK1) is a highly conserved scaffold protein that can assemble multiple kinases and proteins together to form complexes
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March 26, 2025 at 3:49 PM
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Emerging role of MAPK signaling in glycosphingolipid-associated tumorigenesis
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#glycotime #GlycoconjugateJournal
Emerging role of MAPK signaling in glycosphingolipid-associated tumorigenesis
Glycosphingolipids (GSLs) are a type of amphipathic lipid molecules consisting of hydrophobic ceramide backbone bound to carbohydrate moiety clustered in t
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March 26, 2025 at 3:49 PM
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Production of Domain 9 from the cation-independent mannose-6-phosphate receptor fused with an Fc domain
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#glycotime #GlycoconjugateJournal
Production of Domain 9 from the cation-independent mannose-6-phosphate receptor fused with an Fc domain
Lysosomal storage diseases (LSDs) are genetic disorders caused by mutations in lysosomal enzymes, lysosomal membrane proteins or genes related to intracell
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March 26, 2025 at 3:49 PM
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Correction: Production of Domain 9 from the cation-independent mannose-6-phosphate receptor fused with an Fc domain
#glycotime #GlycoconjugateJournal
#glycotime #GlycoconjugateJournal
Correction: Production of Domain 9 from the cation-independent mannose-6-phosphate receptor fused with an Fc domain
Correction: Production of Domain 9 from the cation-independent mannose-6-phosphate receptor fused with an Fc domain
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March 26, 2025 at 3:48 PM
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Processing of N-glycans in the ER and Golgi influences the production of surface sialylated glycoRNA
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#glycotime #GlycoconjugateJournal
Processing of N-glycans in the ER and Golgi influences the production of surface sialylated glycoRNA
Glycoconjugates, including glycans on proteins and lipids, have obtained significant attention due to their critical roles in both intracellular and interc
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March 26, 2025 at 3:48 PM
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Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin
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#glycotime #GlycoconjugateJournal
Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin
Dengue viruses (DENV) are transmitted to humans through mosquito bites and infect millions globally. DENV uses heparan sulfate (HS) for attachment and cell
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March 26, 2025 at 3:48 PM
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MUC1 expression is associated with ST3GAL2 and negatively correlated with the androgen receptor in castration-resistant prostate cancer
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#glycotime #GlycoconjugateJournal
MUC1 expression is associated with ST3GAL2 and negatively correlated with the androgen receptor in castration-resistant prostate cancer
Stage-specific embryonic antigen-4 (SSEA-4) is a developmentally regulated antigen, while expression level of SSEA-4 and / or its synthase ST3GAL2 is assoc
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March 26, 2025 at 3:47 PM
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Effect of CFTR modulators Elexacaftor/Tezacaftor/Ivacaftor on lipid metabolism in human bronchial epithelial cells
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#glycotime #GlycoconjugateJournal
Effect of CFTR modulators Elexacaftor/Tezacaftor/Ivacaftor on lipid metabolism in human bronchial epithelial cells
Cystic Fibrosis (CF) is a life-threatening hereditary disease resulting from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) ge
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March 26, 2025 at 3:47 PM
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SUMOylated GLUT1 inhibited the glycometabolism disorder in chondroctyes during osteoarthritis
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#glycotime #GlycoconjugateJournal
SUMOylated GLUT1 inhibited the glycometabolism disorder in chondroctyes during osteoarthritis
Reduction of glucose transporter 1 (GLUT1), even deletion, may results in cartilage fibrosis and osteoarthritis. This study aims to investigate the SUMOyla
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March 26, 2025 at 3:47 PM
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Inhibition of chondroitin sulphate-degrading enzyme Chondroitinase ABC by dextran sulphate
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#glycotime #GlycoconjugateJournal
Inhibition of chondroitin sulphate-degrading enzyme Chondroitinase ABC by dextran sulphate
Chondroitin sulphate (CS) is a sulphated glycosaminoglycan (GAG) polysaccharide found on proteoglycans (CSPGs) in extracellular and pericellular matrices.
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March 26, 2025 at 3:47 PM
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