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stemcellreports.bsky.social
Loss-of-function analysis of the #Oct4 distal (DE) and proximal enhancers (PE) shows that Oct4 PE and DE are required for primed and naive pluripotency, respectively. Powerful genetic tools to dissect Oct4’s role in #pluripotency & early development. https://ow.ly/JShz50Xo5nz

ISSCR
November 11, 2025 at 5:35 PM
isscr.org
One month left to register! Join the ISSCR PSC-Derived Therapies Symposium in Boston to connect with global leaders advancing ESC- and iPSC-derived cell therapies, learn about the latest in clinical trials, & discover next-gen technologies. Register today 👉 https://bit.ly/4gUEvMs
November 11, 2025 at 1:00 PM
stemcellreports.bsky.social
New #organoid research shows transplanted human stomach organoids can induce gastric insulin-secreting cells in vivo. Potential for future therapeutic development using this technology for insulin-dependent #diabetes. https://ow.ly/88W850Xo2nR

ISSCR | The Gairdner Foundation | SickKids Foundation
November 10, 2025 at 9:10 PM
isscr.org
Find your community with the ISSCR!

Through ISSCR membership, you can connect with inspiring leaders, gain new insights, and be part of a global network advancing stem cell science.

Join today and grow with us 👉 www.isscr.org/membership

Mingxia Gu
November 7, 2025 at 7:00 PM
stemcellreports.bsky.social
Online now! ModulatingJAK2-STAT3 pathway promotes expansion & maturation of human iPSC-derived myogenic progenitor cells; advancing in vitro generation of skeletal muscle progenitor cells for potential cell therapy applications. https://ow.ly/6qAz50XkBvY

Sanford Burnham Prebys | ISSCR
November 7, 2025 at 4:55 PM
isscr.org
Hear from William J. Anderson on why the ISSCR and @harvardmed.bsky.social's new clinician education course is important for healthcare professionals.

Explore the course and register today👉 bit.ly/4mpoh0Q
November 6, 2025 at 10:14 PM
stemcellreports.bsky.social
Online now! An evolutionary conserved role for EZH2-polycomb repressive complex 2 (PRC2) in safeguarding #pluripotency from primitive #endoderm cell fate. #hypoblast #transdifferentiation https://ow.ly/Q2eZ50XkBks

ISSCR | Cell Press | SickKids Foundation | The Gairdner Foundation
November 6, 2025 at 8:00 PM
longtail.news
Feed: "ISSCR News - International Society for Stem Cell Research"
By: Kym Kilbourne on Tuesday, November 4, 2025
Registration and Abstract Submission Open for “20 Years of iPSC Discovery: A Celebration and Vision for the Future,” 20-22 October 2026, Kyoto, Japan
The International Society for Stem Cell Research (ISSCR) today announced that registration and abstract submission are open for the ISSCR International Symposium: 20 Years of iPSC Discovery: A Celebration and Vision for the Future, co-sponsored by the Japanese Society for Regenerative Medicine . Th
www.isscr.org
November 5, 2025 at 7:55 PM
longtail.news
Feed: "ISSCR News - International Society for Stem Cell Research"
By: Kym Kilbourne on Wednesday, November 5, 2025
The ISSCR and Stem Cell Network Launch Global Regenerative Medicine Workforce Development Initiative
The International Society for Stem Cell Research (ISSCR) and the Stem Cell Network (SCN) are pleased to partner to lead a joint initiative and a global conversation on workforce development in regenerative medicine. Through this collaboration, the organizations will examine current challenges and op
www.isscr.org
November 5, 2025 at 7:55 PM
isscr.org
ISSCR & Stem Cell Network are seeking nominations to form a working group of early career scientists & senior trainees in stem cell & regenerative medicine research who will provide perspectives on global workforce development. Nominations are due 5 December. Learn more 👉https://ow.ly/j8uY50Xnlzc
The ISSCR and Stem Cell Network Launch Global Regenerative Medicine Workforce Development Initiative — International Society for Stem Cell Research
The International Society for Stem Cell Research (ISSCR) and the Stem Cell Network (SCN) are pleased to partner to lead a joint initiative and a global conversation on workforce development in regenerative medicine. Through this collaboration, the organizations will examine current challenges and op
ow.ly
November 5, 2025 at 7:30 PM
stemcellreports.bsky.social
New in Stem Cell Reports: Activation of canonical #Wnt signaling increases efficiency for direct reprogramming efficiency into human hepatic progenitor cells https://ow.ly/kcFf50XkB3k

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
November 5, 2025 at 5:10 PM
stemcellreports.bsky.social
New from Mayo Clinic: Differentiation of stem cell-derived pancreatic β-cells induces #circadian clock genes, and transplanted SCβ-cells exhibit circadian rhythms in #insulin secretion & optimize insulin secretion to host’s circadian phase https://ow.ly/XMmg50XkARN

ISSCR
November 4, 2025 at 5:30 PM
stemcellreports.bsky.social
#Hypoxia dynamically alters oligodendrocyte precursor cell (OPC)phenotypes post-stroke; “oxygen tone” as a key regulator of OPC dynamic adaptation after stroke, offering a promising strategy for stroke #celltherapy. https://ow.ly/6k0m50XkAyR

ISSCR | SickKids Foundation | The Gairdner Foundation
November 3, 2025 at 9:40 PM
isscr.org
Advance your research and career by joining the ISSCR member! Connect with a global stem cell network through webinars, International Symposia, the Annual Meeting, networking events, and our Society journal, Stem Cell Reports

Discover the benefits 👉 www.isscr.org/membership
November 3, 2025 at 7:00 PM
stemcellreports.bsky.social
Online now! Extracellular-vesicle-mediated transfer of let-7b/7c promotes the proliferation of transition-state spermatogonia in neonatal mouse testis #intercellularcommunication #spermatogonia https://ow.ly/J0FZ50XhMg3

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
October 31, 2025 at 3:01 PM
longtail.news
Feed: "ISSCR News - International Society for Stem Cell Research"
By: Kym Kilbourne on Thursday, October 30, 2025
Immature Brain-Supporting Cells Switch Fate to Restore Blood Flow After Stroke
Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells. Although brain damage c
www.isscr.org
October 31, 2025 at 7:48 AM
stemcellreports.bsky.social
New mapping review of the philosophical and ethical issues associated with developing and using human #organ-on-chip models. #organoids #personalizedmedicine #digitaltwins #stemcells https://ow.ly/Eqex50XkA1m

ISSCR | The Gairdner Foundation | SickKids Foundation | Cell Press
October 30, 2025 at 8:01 PM
isscr.org
ISSCR joined more than 450 biomedical research organizations to urge U.S. congressional appropriators to provide the NIH with $47.2 billion as approved by the Senate Appropriations Committee for Fiscal Year 2026. Read more. https://ow.ly/qhp650XknOH
October 30, 2025 at 2:30 PM
stemcellreports.bsky.social
New research from Boston Children’s Hospital! Dual reporter mESC line created to study joint lineage cell differentiation & the roles of TGF-β, Wnt, & MAPK signaling pathways in joint lineage specification in vitro & ex vivo https://ow.ly/bo4j50XhLUS ISSCR
October 30, 2025 at 1:55 PM
stemcellreports.bsky.social
Scientists from Roche Innovation Center recently joined The Stem Cell Report podcast to discuss insights from their new model of the blood-brain barrier. Listen to the full episode 👉https://ow.ly/lkRi50Xh6PV ISSCR
October 29, 2025 at 6:20 PM
stemcellreports.bsky.social
The LINC01612-DVL2-WNT regulatory axis promotes human endoderm differentiation – a key modulator of human definitive endoderm differentiation. #longnoncodingRNA #DVL2 #WNT #endoderm https://ow.ly/zvgJ50XhLB8

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
October 29, 2025 at 1:35 PM
stemcellreports.bsky.social
Online now! First comprehensive database of potential cell-cell interactions in liver cell homeostasis & regeneration. Authors identified & validated 2 previously unknown signaling interactions involved in acceleration & delaying liver regeneration https://ow.ly/8ZfM50XhLnj ISSCR
October 28, 2025 at 9:30 PM
stemcellreports.bsky.social
New study maps transcriptomic differences between in vitro skeletal muscle models & in vivo muscle, highlighting targetable processes to improve the models while paving the way for similar studies on other cell types. https://ow.ly/nCXq50XhL0L

ISSCR | The Gairdner Foundation | SickKids Foundation
October 27, 2025 at 8:20 PM
Oh wow - pre-made templates :) - EB
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
I'm speaking at ISSCR 2026 Annual Meeting, join me
Register now
invt.io
October 27, 2025 at 8:15 PM
stemcellreports.bsky.social
New #hematopoiesis research from UW–Madison: GABA produced by multiple bone marrow cell types regulate hematopoietic stem and progenitor cells. #microenvironment #bonemarrow #Bcells https://ow.ly/kSws50XeaPF

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
October 23, 2025 at 7:00 PM