Identification of byakangelicin metabolites in rats via the UHPLC-Q-exactive orbitrap mass spectrometer #JChromB www.sciencedirect.com/science/arti...
Identification of byakangelicin metabolites in rats via the UHPLC-Q-exactive orbitrap mass spectrometer
Byakangelicin is a furanocoumarin derived from the roots of Angelica dahurica. It exhibits pharmacological properties, including anti-tumor activity, …
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November 8, 2025 at 11:33 AM
Identification of byakangelicin metabolites in rats via the UHPLC-Q-exactive orbitrap mass spectrometer #JChromB www.sciencedirect.com/science/arti...
LC-HRMS- and TLC-based metabolomics for the identification and authentication of Sida rhombifolia #JChromB www.sciencedirect.com/science/arti...
LC-HRMS- and TLC-based metabolomics for the identification and authentication of Sida rhombifolia
Ensuring the authenticity and quality of Sida rhombifolia raw materials is crucial for its herbal medicinal product's consistent efficacy, quality, an…
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October 31, 2025 at 9:49 AM
LC-HRMS- and TLC-based metabolomics for the identification and authentication of Sida rhombifolia #JChromB www.sciencedirect.com/science/arti...
An LC-MS/MS method for simultaneous quantification of pyrotinib, docetaxel and paclitaxel in human plasma and its application to therapeutic drug monitoring #JChromB www.sciencedirect.com/science/arti...
An LC-MS/MS method for simultaneous quantification of pyrotinib, docetaxel and paclitaxel in human plasma and its application to therapeutic drug monitoring
Pyrotinib which is a novel irreversible tyrosine kinase inhibitor plus docetaxel or paclitaxel is effective for patients with Her2 positive early or a…
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October 30, 2025 at 11:39 AM
An LC-MS/MS method for simultaneous quantification of pyrotinib, docetaxel and paclitaxel in human plasma and its application to therapeutic drug monitoring #JChromB www.sciencedirect.com/science/arti...
Impact of Preprocessing and data analysis strategies on metabolite annotation in biological samples: A mass spectrometry-based metabolomics study using feature-based molecular networking #JChromB www.sciencedirect.com/science/arti...
Impact of Preprocessing and data analysis strategies on metabolite annotation in biological samples: A mass spectrometry-based metabolomics study using feature-based molecular networking
Metabolomics workflows involve multiple complex steps including sample collection, storage, preparation, metabolite extraction, analytical platforms s…
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October 29, 2025 at 8:10 PM
Impact of Preprocessing and data analysis strategies on metabolite annotation in biological samples: A mass spectrometry-based metabolomics study using feature-based molecular networking #JChromB www.sciencedirect.com/science/arti...
A pharmacokinetic study on punicalagin following oral and intravenous administration to the rat using UPLC-MS/MS #JChromB www.sciencedirect.com/science/arti...
A pharmacokinetic study on punicalagin following oral and intravenous administration to the rat using UPLC-MS/MS
Punicalagin (PUN) is a high abundant ellagitannin and the principal bioactive component existing in Pomegranate (Punica granatum L.) peel, juice, and …
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October 27, 2025 at 9:50 AM
A pharmacokinetic study on punicalagin following oral and intravenous administration to the rat using UPLC-MS/MS #JChromB www.sciencedirect.com/science/arti...
Development and validation of an LC-MS/MS method for Tirzepatide, a dual GIP/GLP-1 receptor agonist, in rat plasma for application to a pharmacokinetic study #JChromB www.sciencedirect.com/science/arti...
Development and validation of an LC-MS/MS method for Tirzepatide, a dual GIP/GLP-1 receptor agonist, in rat plasma for application to a pharmacokinetic study
A sensitive and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of tirzepati…
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October 27, 2025 at 9:49 AM
Development and validation of an LC-MS/MS method for Tirzepatide, a dual GIP/GLP-1 receptor agonist, in rat plasma for application to a pharmacokinetic study #JChromB www.sciencedirect.com/science/arti...
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights #JChromB www.sciencedirect.com/science/arti...
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights
Borbotoxin is an emergent biotoxin produced by Prorocentrum borbonicum and other related dinoflagellates. This toxin is known to produce neuromuscular…
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October 25, 2025 at 6:07 PM
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights #JChromB www.sciencedirect.com/science/arti...
Study on the chemical composition and quality evaluation of Fufangxueteng medicinal wine based on UHPLC-Q orbitrap-HRMS and HPLC combined with fingerprinting and content determination analysis #JChromB www.sciencedirect.com/science/arti...
Study on the chemical composition and quality evaluation of Fufangxueteng medicinal wine based on UHPLC-Q orbitrap-HRMS and HPLC combined with fingerprinting and content determination analysis
This study aims to rapidly identify the chemical components of Fufangxueteng Medicinal Wine (FFXTMW) and establish a quality control method based on f…
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October 25, 2025 at 6:06 PM
Study on the chemical composition and quality evaluation of Fufangxueteng medicinal wine based on UHPLC-Q orbitrap-HRMS and HPLC combined with fingerprinting and content determination analysis #JChromB www.sciencedirect.com/science/arti...
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights #JChromB www.sciencedirect.com/science/arti...
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights
Borbotoxin is an emergent biotoxin produced by Prorocentrum borbonicum and other related dinoflagellates. This toxin is known to produce neuromuscular…
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October 24, 2025 at 10:52 AM
First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights #JChromB www.sciencedirect.com/science/arti...
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry #JChromB www.sciencedirect.com/science/arti...
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry
The combination of isotope-coded derivatization (ICD) and liquid chromatography–tandem mass spectrometry (LC–MS/MS) was an excellent analytical method…
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October 23, 2025 at 7:33 AM
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry #JChromB www.sciencedirect.com/science/arti...
Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay #JChromB www.sciencedirect.com/science/arti...
Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay
A UHPLC-MS/MS method for the detection and quantification of the 6-substituted pyrrolo[2,3-d] pyrimidine AGF94, a novel antifolate, in mouse plasma an…
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October 22, 2025 at 6:20 PM
Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay #JChromB www.sciencedirect.com/science/arti...
Pharmacokinetic profile and bioavailability assessment of rubusoside in mouse plasma utilizing UPLC-MS/MS analysis #JChromB www.sciencedirect.com/science/arti...
Pharmacokinetic profile and bioavailability assessment of rubusoside in mouse plasma utilizing UPLC-MS/MS analysis
The ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) technique was utilized to detect rubusoside in mouse plasma and eval…
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October 22, 2025 at 6:19 PM
Pharmacokinetic profile and bioavailability assessment of rubusoside in mouse plasma utilizing UPLC-MS/MS analysis #JChromB www.sciencedirect.com/science/arti...
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry #JChromB www.sciencedirect.com/science/arti...
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry
The combination of isotope-coded derivatization (ICD) and liquid chromatography–tandem mass spectrometry (LC–MS/MS) was an excellent analytical method…
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October 22, 2025 at 6:19 PM
Novel isotope-coded derivatization of carboxylic acids provides accurate quantification of Azaspiracids in shellfish by liquid chromatography–tandem mass spectrometry #JChromB www.sciencedirect.com/science/arti...
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods #JChromB #MassSpec www.sciencedirect.com/science/arti...
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods
Biomarkers of food intake (BFIs) have emerged as a promising objective tool to complement traditional self-reported dietary assessment in nutritional …
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October 16, 2025 at 8:37 AM
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods #JChromB #MassSpec www.sciencedirect.com/science/arti...
LC-MS-based metabolomics revealed promising role of leukotriene receptor antagonists against colorectal cancer #JChromB www.sciencedirect.com/science/arti...
LC-MS-based metabolomics revealed promising role of leukotriene receptor antagonists against colorectal cancer
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Current treatments are often limited by multidrug res…
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October 16, 2025 at 8:37 AM
LC-MS-based metabolomics revealed promising role of leukotriene receptor antagonists against colorectal cancer #JChromB www.sciencedirect.com/science/arti...
Accurate determination of fluoxetine and its metabolites in Mediterranean mussel organs based on solid phase extraction clean-up and HPLC-HRMS #JChromB www.sciencedirect.com/science/arti...
Accurate determination of fluoxetine and its metabolites in Mediterranean mussel organs based on solid phase extraction clean-up and HPLC-HRMS
Fluoxetine, a widely prescribed antidepressant, is frequently detected in marine environments, exposing marine invertebrates to this emerging contamin…
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October 8, 2025 at 9:10 AM
Accurate determination of fluoxetine and its metabolites in Mediterranean mussel organs based on solid phase extraction clean-up and HPLC-HRMS #JChromB www.sciencedirect.com/science/arti...
A fast GC–MS/MS method for the simultaneous measurement of key metabolites of peroxisomal beta-oxidation and ether lipid biosynthesis in human fibroblasts #JChromB www.sciencedirect.com/science/arti...
A fast GC–MS/MS method for the simultaneous measurement of key metabolites of peroxisomal beta-oxidation and ether lipid biosynthesis in human fibroblasts
Peroxisomes are subcellular compartments that host a variety of metabolic pathways, including the chain shortening of fatty acids (FAs) by beta-oxidat…
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October 6, 2025 at 6:04 PM
A fast GC–MS/MS method for the simultaneous measurement of key metabolites of peroxisomal beta-oxidation and ether lipid biosynthesis in human fibroblasts #JChromB www.sciencedirect.com/science/arti...
Screening biomarkers for diagnosis of COPD by multiplex-high-resolution mass spectrometry based pseudotargeted lipidomics #JChromB www.sciencedirect.com/science/arti...
Screening biomarkers for diagnosis of COPD by multiplex-high-resolution mass spectrometry based pseudotargeted lipidomics
Triple quadrupole (QQQ) MS based pseudotargeted lipidomics combines high coverage and quantitative accuracy, is commonly established by selecting the …
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October 2, 2025 at 2:35 PM
Screening biomarkers for diagnosis of COPD by multiplex-high-resolution mass spectrometry based pseudotargeted lipidomics #JChromB www.sciencedirect.com/science/arti...
Simultaneous determination of six nitrosamines in different pharmaceutical dosage forms by GC–MS/MS with headspace module vs. autosampler solvent vent mode: Development and validation #JChromB www.sciencedirect.com/science/arti...
Simultaneous determination of six nitrosamines in different pharmaceutical dosage forms by GC–MS/MS with headspace module vs. autosampler solvent vent mode: Development and validation
The determination of N-nitrosamines is of significant importance in pharmaceutical drug products. An analytical method was devised and validated in th…
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September 16, 2025 at 12:10 PM
Simultaneous determination of six nitrosamines in different pharmaceutical dosage forms by GC–MS/MS with headspace module vs. autosampler solvent vent mode: Development and validation #JChromB www.sciencedirect.com/science/arti...
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods #JChromB #MassSpec www.sciencedirect.com/science/arti...
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods
Biomarkers of food intake (BFIs) have emerged as a promising objective tool to complement traditional self-reported dietary assessment in nutritional …
www.sciencedirect.com
September 16, 2025 at 12:07 PM
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods #JChromB #MassSpec www.sciencedirect.com/science/arti...
Analysis of eicosanoids by quadrupole gas chromatography-negative ion chemical ionization-tandem mass spectrometry as pentafluorobenzyl trimethylsilyl derivatives: Naming the Murphy rearrangement #JChromB www.sciencedirect.com/science/arti...
Analysis of eicosanoids by quadrupole gas chromatography-negative ion chemical ionization-tandem mass spectrometry as pentafluorobenzyl trimethylsilyl derivatives: Naming the Murphy rearrangement
Eicosatetraenoic acid (arachidonic acid) is the precursor of the eicosanoids, which include the prostaglandins (PGs), the leukotrienes (LTs), and the …
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September 15, 2025 at 6:48 AM
Analysis of eicosanoids by quadrupole gas chromatography-negative ion chemical ionization-tandem mass spectrometry as pentafluorobenzyl trimethylsilyl derivatives: Naming the Murphy rearrangement #JChromB www.sciencedirect.com/science/arti...
GC–MS metabolomics coupled with multi-biomarker analysis reveal toxic effects of functionalized nanoplastics in Paphia undulata #JChromB www.sciencedirect.com/science/arti...
GC–MS metabolomics coupled with multi-biomarker analysis reveal toxic effects of functionalized nanoplastics in Paphia undulata
Despite the widespread occurrence of nanoplastics (NPs) in marine ecosystems, a knowledge gap persists regarding their bioaccumulation and toxic effec…
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September 13, 2025 at 6:34 AM
GC–MS metabolomics coupled with multi-biomarker analysis reveal toxic effects of functionalized nanoplastics in Paphia undulata #JChromB www.sciencedirect.com/science/arti...
Development and validation of general urine screening method for performance enhancing drugs in racehorses utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS) #JChromB www.sciencedirect.com/science/arti...
Development and validation of general urine screening method for performance enhancing drugs in racehorses utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS)
The complexity of the drug market and the constant updating of drugs have been challenging issues for drug regulatory authorities. In this manuscript,…
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September 11, 2025 at 6:40 AM
Development and validation of general urine screening method for performance enhancing drugs in racehorses utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS) #JChromB www.sciencedirect.com/science/arti...
Comprehensive LC-MS/MS and HPLC-based profiling of secondary metabolites in Aster incisus from diverse cultivation regions #JChromB www.sciencedirect.com/science/arti...
Comprehensive LC-MS/MS and HPLC-based profiling of secondary metabolites in Aster incisus from diverse cultivation regions
Aster incisus is a perennial herbaceous plant belonging to the Asteraceae family, known for its pharmacologically active secondary metabolites. In thi…
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September 3, 2025 at 7:56 AM
Comprehensive LC-MS/MS and HPLC-based profiling of secondary metabolites in Aster incisus from diverse cultivation regions #JChromB www.sciencedirect.com/science/arti...
Discrimination of isomeric dihydroflavone and chalcone by the boosting optimal collision energy-liquid chromatography-tandem mass spectrometry: A case study of pharmacokinetics in honey-fried licorice #JChromB www.sciencedirect.com/science/arti...
Discrimination of isomeric dihydroflavone and chalcone by the boosting optimal collision energy-liquid chromatography-tandem mass spectrometry: A case study of pharmacokinetics in honey-fried licorice
The occurrence of isomeric dihydroflavone and chalcone, two important subfamilies of flavonoid class, extensively happens in herbal medicines. However…
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September 3, 2025 at 7:55 AM
Discrimination of isomeric dihydroflavone and chalcone by the boosting optimal collision energy-liquid chromatography-tandem mass spectrometry: A case study of pharmacokinetics in honey-fried licorice #JChromB www.sciencedirect.com/science/arti...