Princeton's Ploss Lab leads effort to show how key mutations in the Yellow Fever E and NS2A proteins drive attenuation—altering viral spread & boosting interferon responses. A roadmap for future live-attenuated vaccines. go.njmicrobe.org/ppRtE2 #Virology #Vaccinology #LiveAttenuatedVaccines
Yellow Fever 17D's Attenuation: A Blueprint for Next-Generation Live-Attenuated Vaccines
The Yellow Fever (YF) 17D vaccine, developed in the 1930s, stands as a triumph in vaccinology, recognized as one of the most potent and durable vaccines known. Despite its widespread success, having b...
go.njmicrobe.org
August 16, 2025 at 1:27 PM
Princeton's Ploss Lab leads effort to show how key mutations in the Yellow Fever E and NS2A proteins drive attenuation—altering viral spread & boosting interferon responses. A roadmap for future live-attenuated vaccines. go.njmicrobe.org/ppRtE2 #Virology #Vaccinology #LiveAttenuatedVaccines