#PainResearch🛟
Researchers at the Yale School of Medicine investigated the therapeutic potential of IgG- and IgM-specific proteases against the acetylcholine receptor antibodies found in myasthenia gravis, an autoimmune disorder.

#MyastheniaGravis #Autoimmune #Immunology

www.pnas.org/doi/10.1073/...
November 3, 2025 at 5:31 PM
VERY TROUBLING NEWS REGARDING NIH INSTITUTE DIRECTORS

A new appointment for NIEHS

1/3
October 18, 2025 at 1:28 PM
FIGHT FOR SCIENCE RALLY ✊🌏
⏰ WHEN: October 17th, 2025
📍WHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM ‼️

📲 Join us Virtually!: zurl.co/Um47l
October 17, 2025 at 1:35 AM
#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #neuroskyence #neurosci #PainResearch 🧪🛟 🫁💊

This is big, @fda.gov acknowledging that vaping addiction has become such a big problem that a treatment needs to be fast-tracked:

FDA prioritizes cytisinicline for nicotine vaping addiction
FDA Awards First-Ever National Priority Vouchers to Nine Sponsors
FDA Awards First-Ever National Priority Vouchers to Nine Sponsors
www.fda.gov
October 16, 2025 at 9:16 PM
#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence #neurosci #PainResearch 🧪🛟 🫁💊
Smoking has long been known to negatively affect surgical outcomes. A new study demonstrates that non-tobacco nicotine products (e-cigarettes and nicotine pouches) do the same.
Non-tobacco nicotine dependence increases risk of complications following lumbar spine decompression and fusion
Non-tobacco nicotine products (eg, e-cigarettes, nicotine pouches) are increasingly used by cigarette smokers and prior nonsmokers. While the detrimen…
www.sciencedirect.com
October 16, 2025 at 1:34 PM
npr.org NPR @npr.org · Oct 1
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Jane Goodall, legendary primatologist, has died at age 91
Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
n.pr
October 1, 2025 at 7:48 PM
A landmark new study in JAMA Pediatrics shows the HPV vaccine is doing exactly what it promised & more. 17yrs after rollout, adolescent vaccination has slashed HPV infxns not only among those vaccinated but also those unvaccinated, showing powerful herd protection.
jamanetwork.com/journals/jam...
Population-Level Effectiveness and Herd Protection 17 Years After HPV Vaccine
This cross-sectional study investigates population-level effectiveness and herd protection in the first 17 years after human papillomavirus (HPV) vaccination among adolescent girls and young women at ...
jamanetwork.com
October 1, 2025 at 3:11 PM
#PedSky #MedSky #EpiSky #policysky #polisky #neuroskyence #neurosci #PainResearch 🧪🛟💊
More success for gene therapy approaches, this time for Hereditary transthyretin amyloidosis with polyneuropathy, an extremely painful deadly disease affecting peripheral nerves.
#ScienceSaves
nejm.org NEJM.org @nejm.org · Sep 25
Presented at #ATTR:

Gillmore and colleagues report 24-month results from a phase 1 study of nexiguran ziclumeran, a CRISPR gene-editing approach to treating hereditary transthyretin amyloidosis with polyneuropathy. Full study results: nej.md/46Qhur7

#MedSky #NeuroSky #Genetics
September 25, 2025 at 2:06 PM
#PedSky #MedSky #EpiSky #policysky #polisky #neuroskyence #neurosci #PainResearch 🧪🛟 💊

European Medicines Agency keeps recommendations on acetaminophen / paracetamol unchanged.
September 23, 2025 at 12:47 PM
May 6, 2025 at 6:07 PM
#PedSky #MedSky #EpiSky #policysky #polisky #neuroskyence #neurosci #PainResearch #addictionsci 🧪🛟

This is peak intramural NIH research, from NINDS, NIDCR NCCIH, advancing understanding of pain.

A distributed coding logic for thermosensation and inflammatory pain
www.nature.com/articles/s41...
A distributed coding logic for thermosensation and inflammatory pain - Nature
Functional imaging and multiplexed in situ hybridization were combined to investigate how trigeminal neurons encode heat and mechanical stimuli, revealing distinct cellular mechanisms for continuing p...
www.nature.com
April 25, 2025 at 1:49 PM
cnn.com CNN @cnn.com · Sep 6
Jerome Adams, who served as US surgeon general during President Donald Trump’s first administration, is calling for Health and Human Services Secretary Robert F. Kennedy Jr. to be fired as controversy continues to swirl over his handling of vaccine approvals. https://cnn.it/47s9lKt
September 6, 2025 at 9:17 PM
New study with combined 7 Tesla MRI imaging and PET scan finds altered structures of nerves and neuroinflammation in migraine patients. Vey robust design that includes a control group and same cases as right/left side dominant migraines as controls.
#painresearch
#neuroskyence
#physio
🧪🛟
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine
Using multimodal imaging, Tohyama et al. show that individuals with migraine have white matter damage in the trigeminal nerve. This damage is associated wi
academic.oup.com
February 6, 2025 at 10:05 AM
#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #PainResearch🛟 🫁

Cases of poisoning by nicotine pouches in children have increased recently. FDA urges manufacturers to introduce child-proof packaging.
FDA Urges Nicotine Pouch Manufacturers To Use Child-Resistant Packaging Following Increasing Reports of Accidental Exposure
The U.S. Food and Drug Administration calls on nicotine pouch manufacturers to use child-resistant packaging to protect American children from accidental, harmful exposure.
www.fda.gov
September 2, 2025 at 4:56 PM
Yay! Timely that FINALLY @bmjtobacco-control.bsky.social is ON BLUE SKY! Give them a follow — top journal for tobacco policy research and analysis @mhef.bsky.social
@kamranabbasi.bsky.social
August 27, 2025 at 2:29 PM
Striking cases of neuro-immune interactions: Upper pic: Psoriasis vanished from right hand after shoulder dislocation with brachial plexus injury. Bottom pic: Four months later, as nerves began to recover, psoriasis returned.
#neuroskyence
#painresearch
#physio
🧪🛟
February 8, 2025 at 3:15 PM
#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence #PainResearch #biotechfeed🛟💊 🧪 More than 99% of all new drugs approved from 2010 through 2019 in the US were developed based on NIH-funded basic research. Planned cuts will reduce this effort by one-third.
Trump Seeks to Cut Basic Scientific Research by Roughly One-Third, Report Shows
www.nytimes.com
July 10, 2025 at 3:45 PM
who.int WHO @who.int · May 30
Today is #WorldNoTobaccoDay 🚭

Tobacco and nicotine products look sweet BUT are harmful
#TobaccoExposed

That bubblegum, mango, or cotton candy flavour isn’t just for taste. It’s a trap to get young people hooked!

Don’t fall for the illusion. Unmask the appeal 👉 bit.ly/NoTobacco2025
May 31, 2025 at 2:17 PM