β-Nicotyrine and e-cigarette abuse liability I: Pharmacodynamics and interaction with pharmacokinetics and discriminative stimulus effects of nicotine in rats
pubmed.ncbi.nlm.nih.gov/41176900/
pubmed.ncbi.nlm.nih.gov/41176900/
β-Nicotyrine and e-cigarette abuse liability I: Pharmacodynamics and interaction with pharmacokinetics and discriminative stimulus effects of nicotine in rats - PubMed
β-Nic slows Nic clearance in rats and enhances and prolongs the discriminative stimulus effects of Nic, suggesting it may contribute to the abuse liability of ENDS.
pubmed.ncbi.nlm.nih.gov
November 4, 2025 at 2:00 PM
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Labreche MJ, Graber CJ, Nguyen HM. Recent Updates on the Role of Pharmacokinetics-pharmacodynamics in Antimicrobial Susceptibility Testing as Applied to Clinical Practice. Saravolatz LD, ed. Clinical Infectious Diseases. 2015;61(9):1446-1452. doi:https://doi.org/10.1093/cid/civ498
October 24, 2025 at 10:23 PM
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ACM Biolabs Reports Promising Safety Profile and Early Pharmacodynamics for Intramuscular ACM-CpG in Advanced Cancer Patients#Singapore#Immunotherapy#ACM_Biolabs#ACM-CpG
ACM Biolabs Reports Promising Safety Profile and Early Pharmacodynamics for Intramuscular ACM-CpG in Advanced Cancer Patients
ACM Biolabs shares preliminary findings that suggest a favorable safety and early pharmacodynamic profile for their ACM-CpG treatment in advanced solid tumor patients.
third-news.com
October 22, 2025 at 6:04 AM
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in search of: a job that combines medical devices/implants, imaging techniques, pharmacodynamics and kinetics, some form of humanities (linguistics, journalism, etcetera) if not law, and some form of coding/computation if not outright cybersecurity/pentesting. 💔💔💔💔💔
October 19, 2025 at 5:59 PM
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October 17, 2025 at 6:29 AM
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Pharmacology and artificial intelligence
A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance
www.em-consulte.com/article/1768...
A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance
www.em-consulte.com/article/1768...
A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance
A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance
www.em-consulte.com
October 17, 2025 at 6:28 AM
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This narrative review examines how genetic variations impact the pharmacokinetics and pharmacodynamics of buprenorphine, a crucial medication for treating opioid use disorder and managing pain.
October 14, 2025 at 1:47 AM
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You're just restating the pharmacodynamics, not the treatment goal.
A hammer’s mechanism is to deliver kinetic force through a flat surface. The hammer's *purpose* is to drive nails into objects
A hammer’s mechanism is to deliver kinetic force through a flat surface. The hammer's *purpose* is to drive nails into objects
October 13, 2025 at 3:14 AM
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Antipsychotic Combinations: Dopamine Receptor Occupancy Explained
In an era where the nuanced treatment of psychiatric disorders hinges critically on our understanding of brain chemistry, a groundbreaking study has emerged, shedding unprecedented light on the pharmacodynamics of antipsychotic drug…
In an era where the nuanced treatment of psychiatric disorders hinges critically on our understanding of brain chemistry, a groundbreaking study has emerged, shedding unprecedented light on the pharmacodynamics of antipsychotic drug…
Antipsychotic Combinations: Dopamine Receptor Occupancy Explained
In an era where the nuanced treatment of psychiatric disorders hinges critically on our understanding of brain chemistry, a groundbreaking study has emerged, shedding unprecedented light on the pharmacodynamics of antipsychotic drug combinations. Published in Translational Psychiatry, this research by Spangemacher et al. tackles one of the most complex puzzles in psychopharmacology: how the simultaneous use of multiple antipsychotic drugs influences dopamine D2/D3 receptor occupancy, a pivotal factor in the treatment of disorders such as schizophrenia.
scienmag.com
October 1, 2025 at 12:46 PM
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ICYMI: Effect of food on pravastatin pharmacokinetics and pharmacodynamics
Effect of food on pravastatin pharmacokinetics and pharmacodynamics
The pharmacokinetics and pharmacodynamics of pravastatin 20 mg administered twice daily when taken with or one hour before meals were evaluated in 24 hypercholesterolemic men in an 8-week, open-label, randomized, two-way crossover study. Th...
eurekamag.com
September 30, 2025 at 2:37 PM
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📢 Coming soon... Essential Pharmacology in Paramedic Practice
🔹 Overview of pharmacological principles
🔹 Clear explanations of medicine law, PGDs & adverse drug reactions
🔹 A-Z guide of key drugs, explaining the pharmacodynamics & pharmacokinetics for each
And more! ➡ bit.ly/EssentialPharmacology
🔹 Overview of pharmacological principles
🔹 Clear explanations of medicine law, PGDs & adverse drug reactions
🔹 A-Z guide of key drugs, explaining the pharmacodynamics & pharmacokinetics for each
And more! ➡ bit.ly/EssentialPharmacology
September 30, 2025 at 2:33 PM
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Effect of food on pravastatin pharmacokinetics and pharmacodynamics
Effect of food on pravastatin pharmacokinetics and pharmacodynamics
The pharmacokinetics and pharmacodynamics of pravastatin 20 mg administered twice daily when taken with or one hour before meals were evaluated in 24 hypercholesterolemic men in an 8-week, open-label, randomized, two-way crossover study. Th...
eurekamag.com
September 29, 2025 at 2:36 PM
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Pharmacodynamics of Vancomycin Against Coagulase-Negative Staphylococci Bloodstream Infections t.co/qcHIktLJBd
Pharmacodynamics of Vancomycin Against Coagulase-Negative Staphylococci Bloodstream Infections - PubMed
The recommended therapeutic target for vancomycin for serious methicillin-resistant S. aureus infections is an area under the concentration-time curve (AUC) over 24 h to a minimum inhibitory concentration...
t.co
September 28, 2025 at 8:42 PM
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HSD3B1 genotype among metastatic castration-resistant prostate cancer patients: pharmacodynamics and clinical outcomes after treatment with abiraterone plus prednisone https://www.medrxiv.org/content/10.1101/2025.09.17.25335890v1
September 18, 2025 at 4:30 PM
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The Effects of Cobicistat and Voriconazole on the Safety, Pharmacokinetics, and Pharmacodynamics of the TLR7 Agonist Vesatolimod in People with #HIV link.springer.com/article/10.1... (open access)
The Effects of Cobicistat and Voriconazole on the Safety, Pharmacokinetics, and Pharmacodynamics of the TLR7 Agonist Vesatolimod in People with HIV - Infectious Diseases and Therapy
Introduction Vesatolimod (VES), a toll-like receptor 7 agonist, is being investigated as part of a strategy for human immunodeficiency virus (HIV) cure. VES is metabolized through the CYP3A pathway an...
link.springer.com
September 15, 2025 at 10:19 PM
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This controlled study examined the pharmacokinetics and pharmacodynamics of oral cannabidiol (CBD) with varying low doses of delta-9-tetrahydrocannabinol (Δ9-THC) in healthy adults.
September 12, 2025 at 10:40 PM
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Word of the Week: Pharmacodynamics! 💊 How drugs interact with our bodies at the cellular level—essential for safe dosing, predicting drug interactions & developing better treatments. Send suggestions for other words to explore! #Pharmacodynamics #WordOfTheWeek #PharmaceuticalScience #ScienceEveryday
September 10, 2025 at 11:00 PM
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The researchers characterized the effects on E3-ligase engagement, degradation kinetics, plasma stability, and brain/plasma pharmacokinetics and pharmacodynamics.
September 9, 2025 at 1:13 PM
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Relance : Il reste des places pour assister à cet atelier du mardi 16 sept à 18h30.
Inscrivez vous pour recevoir vos accès.
Explication d’un article scientifique : "Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of FA".
En savoir plus : www.afaf.asso.fr/.../mardi-16...
Inscrivez vous pour recevoir vos accès.
Explication d’un article scientifique : "Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of FA".
En savoir plus : www.afaf.asso.fr/.../mardi-16...
Mardi 16 septembre à 18 h 30 – Atelier visio N°21 : Lecture critique d’article (explication de texte scientifique) - Association Française Ataxie de Friedreich
le mardi 16 septembre à 18h30 L’AFAF vous propose une prochaine session d’explication d’un article scientifique, à partir de l’article suivant: Pharmacokinetics and Pharmacodynamics of Nomlabofusp in ...
www.afaf.asso.fr
September 9, 2025 at 9:12 AM
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Thanks for sharing. Great to read the actual paper having seen it referenced a few times (usually claiming it supports S-shaped on/off pharmacodynamics). Table 2 is relatable chaos of diuretic prescribing
September 8, 2025 at 7:58 PM
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This phase IIa, single-blind, placebo-controlled trial assessed the pharmacokinetics, pharmacodynamics, safety, and tolerability of brensocatib in 29 adults with cystic fibrosis.
September 6, 2025 at 10:08 AM
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L’AFAF vous propose une prochaine session d’explication d’un article scientifique, à partir de l’article suivant : "Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of Friedreich’s Ataxia".
En savoir plus : www.afaf.asso.fr/.../mardi-16...
En savoir plus : www.afaf.asso.fr/.../mardi-16...
Mardi 16 septembre à 18 h 30 – Atelier visio N°21 : Lecture critique d’article (explication de texte scientifique) - Association Française Ataxie de Friedreich
le mardi 16 septembre à 18h30 L’AFAF vous propose une prochaine session d’explication d’un article scientifique, à partir de l’article suivant: Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of Friedreich’s Ataxia.( Pharmacocinétique et pharmacodynamie du Nomlabofusp dans des études non cliniques de l’Ataxie de Friedreich), publié en juin 2025 dans the AAPS journal, et disponible […]
www.afaf.asso.fr
September 4, 2025 at 9:45 AM
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While these drugs offer prolonged bronchodilation and symptom control in adults, their use in children presents unique challenges, including age-specific pharmacodynamics, safety concerns, and the need for appropriate combination therapies.
September 1, 2025 at 4:10 PM
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Pharmacokinetics, pharmacodynamics, efficacy and drug resistance selection of injectable long-acting lenacapavir pre-exposure prophylaxis (PrEP) against HIV https://www.medrxiv.org/content/10.1101/2025.08.26.25334527v1
August 29, 2025 at 12:42 AM
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