#SüssmuthLab
#SüssmuthLab We have investigated the structure, bioactivity, and biosynthesis of AFC-BC11, an antifungal lipopeptide whose structure has remained unresolved since its discovery in 1998. Just published in JACS (@jacs.acspublications.org):
#NaturalProduct #Antifungal 🇩🇪🇫🇷
The Intricate Nonribosomal Assembly of a Potent Antifungal Lipopeptide from the Burkholderia cepacia Complex
The Burkholderia cepacia complex (BCC) is a group of Gram-negative bacteria known for their pathogenicity to patients suffering from cystic fibrosis (CF). The BCC-belonging strain B. pyrrocinia BC11 (...
pubs.acs.org
June 3, 2025 at 9:06 AM