#SGP25
Failure Analysis Chemical Technician - SGP25 - Singapore - Depot 2 (office) (SGP25) Job educativ.net/jobs/job/33797...
March 18, 2025 at 6:43 PM
A huge thank you to all the amazing delegates who joined us for Small G Proteins in Cellular Signalling and Disease 2025 this week! We hope you enjoyed the conference and look forward to seeing you at the next one. #BiochemEvent #SGP25 🧪
June 27, 2025 at 12:44 PM
We have spent four great days talking about Small G proteins. Thanks Angeliki Malliri, @ianprior.bsky.social @biochemsoc.bsky.social for the invitation and the organization #BiochemEvent #SGP25
A huge thank you to all the amazing delegates who joined us for Small G Proteins in Cellular Signalling and Disease 2025 this week! We hope you enjoyed the conference and look forward to seeing you at the next one. #BiochemEvent #SGP25 🧪
June 27, 2025 at 9:23 PM
And we continue #SGP25 with

🔬RAP1GDS1 isoform specific importance in lung cancer

🧫 how kRas oncogenic enhanced proliferation can occur without hyperactive ERK or Akt

🧬 RhoGAP family interactions in endometrial cancer

@biochemsoc.bsky.social #BiochemEvent
June 25, 2025 at 10:51 AM
Don't miss out! The earlybird discount and abstract submission deadline for our upcoming small G protein conference is this Thursday 24 April! Submit your abstract for consideration and register now to save £50! #SGP25 🧪
www.eventsforce.net/biochemsoc/2...
April 22, 2025 at 9:39 AM
Now some adhesion and migration at #SGP25

🔬 hunting for Ras allies
🧫 polarised trafficking regulation adaptability during change
🧬 RhoA and Cdc42 pathway crosstalk

Now onto the party!

@biochemsoc.bsky.social #BiochemEvent
June 26, 2025 at 3:29 PM
SGP25 Sessions 4 & 5:
🧬 Lipid sensing, β-catenin, and phosphorylation reshape GTPase signalling
⚙️ Mechanical forces & trafficking: nuclear F-actin, actin-Rab27a, plexins, and COL1
⚡️Cancer cell adaptation through RhoA/NFAT, Rac1 SUMOylation, and KRAS rewiring
@biochemsoc.bsky.social #BiochemEvent
June 27, 2025 at 7:36 AM
SGP25 Session 3:
⛓️ Tri-complex inhibitor as molecular glue for oncogenic RAS
💊 Combining inhibitors to combat KRAS-driven cancer
🎯 p120RasGAP molecular glue targeting RAS
🔢 Mathematical modelling to study RAS activity
🧐 RAS/RAL, Cdc42, RhoG, RAC1, EPAC2, RalGAP…
@biochemsoc.bsky.social #BiochemEvent
June 25, 2025 at 6:42 PM
We show many more experiments across different implicit surface representations in our paper. Please check out our #SGP25 paper here arxiv.org/pdf/2506.05268 and reach out if you have any questions! Code coming soon! (9/9)
arxiv.org
June 10, 2025 at 2:40 PM
SGP25 Session 1 (Part 1):
⛓️ Mapping KRAS interactomes in organoid models
🧬 Isoform-specific KRAS vulnerabilities: one mutation, big difference
🔬 Novel tool tracks Ras mutation dynamics in vivo
✨ And a reminder that clear science communication empowers patients!
@biochemsoc.bsky.social #BiochemEvent
June 24, 2025 at 6:09 PM
4 weeks left for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @biochemsoc.bsky.social @smallgtpases.bsky.social Register here: bit.ly/SmallG25
Small G proteins in cellular signalling and disease 2025
bit.ly
March 20, 2025 at 7:06 PM
SGP25 Session 2 (Part 1):
⚙️ “Branchgetic” Ras mutations indicate effector selection
🔬 RAF biosensors to monitor acivity in live cells
💥 C2 domain boosts RasGAP activity
💊 RhoB-Ral complex a target for EGFR TK inhibition?
@biochemsoc.bsky.social #BiochemEvent
June 25, 2025 at 10:00 AM
Day 2 of #SGP25 of to a great start with

✨ unpicking Ras effector binding in different tissues
✨ developing RAF based biosensors
✨ C2 domains and GAP functionality
✨ how RhoB and Ral affect EGFT therapy in lung cancer

@Biochemsoc #BiochemEvent
June 25, 2025 at 9:12 AM
Our #SGP25 work studies a simple and effective way to uniformly sample implicit surfaces by casting rays. (1/9)

“Uniform Sampling of Surfaces by Casting Rays” w/ @abhishekmadan.bsky.social @nmwsharp.bsky.social and Alec Jacobson
June 10, 2025 at 2:40 PM
Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
Small G proteins in cellular signalling and disease 2025
bit.ly
April 22, 2025 at 4:58 PM
SGP25 Session 2 (Part 2):
🧬 RAP1GDS1 isoform regulates KRAS signalling & lysosomal function in lung adenocarcinoma
❓Oncogenic KRAS may not alter Akt/ERK pathways
☠️ p190RhoGAP paralogs show synthetic lethality in endometrial cancer

@biochemsoc.bsky.social #BiochemEvent
June 25, 2025 at 2:46 PM
As day 3 of #SGP25 opens we heard brilliants talks covering…

🔬Ras lipid sensing to control localisation
🧫 Rnd3/RhoE importance in hepatocellular carcinoma
🔥 the role of Cdc42 in inflammation in response to wildfire smoke
🧪 the RhoA mutational landscape

@biochemsoc.bsky.social #BiochemEvent
June 26, 2025 at 9:27 AM
My lab and I were at the Small G-Protein conference in Manchester last week. Really lucky to work with such a great team. #BiochemEvent #SGP25 @biochemsoc.bsky.social @livunihls.bsky.social
July 1, 2025 at 8:11 PM
🎉🎖️We congratulate 🌟Jesús Daniel Gómez-Zepeda (IDIBAPS, Barcelona, Spain) on winning the FEBS Letters #PosterPrize at the @biochemsoc.bsky.social meeting on small #Gproteins, recently held in Manchester, UK! 🎉👏👏👏

#SGP25 #Gproteins25
July 23, 2025 at 11:12 AM
Now some adhesion and migration at #SGP25

🔬mechanosensing in cancer development
🧫 Rac1 driven plasticity in small cell lung cancer
🧬 actin in organelle transport
🧪 tool development to study spatial organisation of receptors

@biochemsoc.bsky.social #BiochemEvent
June 26, 2025 at 1:52 PM
Join us in Manchester in 2025 for the next instalment of the Biochemical Society Small G-protein meeting! #SGP25
November 16, 2024 at 10:25 AM
SGP25 Session 1 (Part 2):
🧫 Overcoming RAS resistance: biobanking & precision medicine
💊 Adaptive immunity could enhance KRAS inhibitor activity
🔬 Organoids reveal allele-specific tumour growth
💥 Plus ARL15, RhoGDI1, RalGEF, SOS1/2 & proteomics pipelines
@biochemsoc.bsky.social #BiochemEvent
June 24, 2025 at 9:40 PM
Day 1 of the Small G Proteins in Cellular Signalling and Disease 2025 conference featured multiple inspiring talks, a dynamic poster session, and great networking opportunities. Excited for Day 2 and all that’s still to come! 🧪 #BiochemEvent #SGP25
June 25, 2025 at 12:59 PM