#TCellExhaustion
New research links #MECFS to T cell exhaustion—immune cells worn out from chronic activation. This isn’t “just fatigue,” it’s a biological crisis. We need urgent investment in ME/CFS research and real answers for millions suffering. #pwME #TcellExhaustion #ScienceMatters
May 26, 2025 at 8:53 PM
Epigenetics Review - Epigenetic regulation of T cell exhaustion in cancer go.nature.com/4ohBOrZ

Ben Youngblood (St. Jude Children's Research Hospital) reporting in Nat Rev Cancer

#Epigenetics #Review #TCellExhaustion #Cancer
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High-resolution insights without cell sorting; epigenometech.com
Epigenetic regulation of T cell exhaustion in cancer - Nature Reviews Cancer
Transcriptional and epigenetic mechanisms governing T cell exhaustion substantially impact immunotherapy effectiveness. In this Review, Kang et al. outline epigenetic regulatory programmes that i...
go.nature.com
November 3, 2025 at 9:01 AM
Disulfide stress → disulfidptosis in CD8+ T cells? Big!

We explored similar redox targets in our recent Substack - cystine import, GSH, ferroptosis, and how to collapse tumor defense for <$20.

atorchbearer.substack.com/p/the-20-can...

Curious to hear from you!
#CancerCure #TCellExhaustion #Tumor
The $20 Cure That Terrifies Big Pharma
I Solved Cancer, Neuroinflammation, and Mitochondrial Dysfunction. Here’s the math, and the proof. Real data. Real images. Real results.
atorchbearer.substack.com
July 7, 2025 at 3:51 PM
Excited to share my first post & see the second part of my PhD work published! Our study on mTNBC highlights that baseline clonal expansion of dysfunctional CD8 cells is linked to better response to chemoimmunotherapy.
More here: www.sciencedirect.com/science/arti...

#CD8 #TCellExhaustion #TNBC
Continuous replenishment of the dysfunctional CD8 T cell axis is associated with response to chemoimmunotherapy in advanced breast cancer
Chemotherapy combined with immune checkpoint blockade has shown clinical activity in breast cancer. Response, however, occurs in only a low proportion…
www.sciencedirect.com
March 10, 2025 at 5:54 PM
Honored to share our latest paper on T-Cell Exhaustion's role in Post-Acute Infection Syndromes, now features YouTube!
Watch here: www.youtube.com/watch?v=WSNV...
#Immunology #TCellExhaustion #LongCOVID #ImmuneDysfunction #MedicalResearch #HealthcareInnovation #Qeios
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July 12, 2025 at 7:31 AM
I read the med journal on T-Cell exhaustion. Then, these two trailblazers who research and treat make the time to produce a podcast. Thank you. #ChronicIllness #Immunology #Virology #Microbiology #Neuroscience #TCellExhaustion #Autoimmune
January 5, 2025 at 7:57 PM
#MedSky🧪 #IDSky #Immunosky #publichealth Very interesting study Persistent antigen stimulation, as in cancer and chronic
infections, results in #Tcellexhaustion (TEX) a state of
impaired effector functions.
December 14, 2024 at 7:38 PM