#assay
LightNews LightNews
mackayim.bsky.social
Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀
@mackayim.bsky.social
"After nearly a decade of MeVA [PCR] assay use at the National Microbiology Laboratory (NML), this has been the first documented instance of a false-negative result due to sequence variation"

-But detected thanks to quality & professional lab processes🥼💪

www.eurosurveillance.org/content/10.2...
Measles vaccine virus mutation following vaccination in a healthy child resulting in a false negative vaccine specific PCR test: Ontario, Canada, 2025
We report a case of a mild, self-limited rash illness in a child 18 days after measles-mumps-rubella-varicella vaccination. Initial testing with a PCR-based method failed to detect vaccine virus. Sequencing later identified a novel mutation in the probe-binding site of the vaccine assay that had arisen after vaccination and resulted in the false-negative PCR test results.
www.eurosurveillance.org
October 31, 2025 at 10:33 PM Everybody can reply
2 reposts 5 likes 1 saves
2 5
takomexplore.bsky.social
Takom Exploration
@takomexplore.bsky.social
Ore Odyssey October 30:
Drilling programs, assay results, a property agreement, a permit application, targets, and an ore purchase agreement for projects in BC and the YT.

takomexploration.com/so/38PexS9iR...

#BritishColumbia #Yukon #MineralExploration #Mining #News #NewsReleases
Ore Odyssey
Real news.
takomexploration.com
October 31, 2025 at 8:57 PM Everybody can reply
medrxivpreprint.bsky.social
medRxivpreprint
@medrxivpreprint.bsky.social
Refined fully automated RT-qPCR assay for simultaneous detection of SARS-CoV-2, Influenza A/B, and RSV with target optimization for improved variant resilience https://www.medrxiv.org/content/10.1101/2025.10.29.25339068v1
October 31, 2025 at 7:43 PM Everybody can reply
kinetoplastpapers.bsky.social
kinetoplastids papers
@kinetoplastpapers.bsky.social
Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections pubmed.ncbi.nlm.nih.gov/41165401/
October 31, 2025 at 6:05 PM Everybody can reply
helixbrief.bsky.social
The Helix Brief
@helixbrief.bsky.social
Notably, the TRACT assay also revealed direct 5-HT2A receptor modulation by certain compounds, highlighting its versatility.
October 31, 2025 at 5:26 PM Everybody can reply
1
helixbrief.bsky.social
The Helix Brief
@helixbrief.bsky.social
The TRACT assay was successfully applied to various antidepressants and a designer drug, providing potency values consistent with established uptake assays.
October 31, 2025 at 5:26 PM Everybody can reply
1
helixbrief.bsky.social
The Helix Brief
@helixbrief.bsky.social
The assay leverages SERT-mediated serotonin uptake and subsequent activation of a co-expressed modified serotonin 2A receptor, which is monitored via a luminescent readout.
October 31, 2025 at 5:26 PM Everybody can reply
1
helixbrief.bsky.social
The Helix Brief
@helixbrief.bsky.social
This study developed and evaluated the TRACT (transporter activity through receptor activation) assay to assess SERT inhibition.
October 31, 2025 at 5:26 PM Everybody can reply
1
epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
Our expansion of single-cell epigenetics assays continues!

The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform

Learn more here: lnkd.in/g3YqPrWY

#epigenetics #BDrhapsody #CUTandTag #Chromatin #multiomics #singlecell #CUTandRUN #ChIPseq #ATACseq
October 31, 2025 at 4:50 PM Everybody can reply
arborassays.bsky.social
Arbor Assays
@arborassays.bsky.social
🐘See you at #ISWE9! Today we highlight #ISWE members Danielle Chusyd, Nicole Boisseau, Janine Brown, Steve Paris, & Michael Wasserman, on their #research on how being orphaned affects #elephants
Follow the herd➡️http://bit.ly/4hA7JRU
#Wildlife #Science #Assay #Conservation
October 31, 2025 at 3:18 PM Everybody can reply
1 likes
1
biocompare.bsky.social
Biocompare
@biocompare.bsky.social
3D cell cultures offer major advantages over 2D systems, but optimizing them can be tricky. Learn practical tips for generating and handling spheroids and improving assay results.

www.biocompare.com/Bench-Tips/6...
How to Optimize 3D Spheroid Assays
Optimization starts with proper generation & handling of spheroids.
www.biocompare.com
October 31, 2025 at 1:59 PM Everybody can reply
1 reposts 1 likes
1 1
uniwalespress.bsky.social
University of Wales Press
@uniwalespress.bsky.social
Out now!

'Joseph Harris: Scientist, Artisan, Assay Master' by Martin Griffiths explores the varied life of a man who made a lasting impression on some of the most illustrious scientists of his day.

📚 www.uwp.co.uk/book/joseph-...
Joseph Harris was destined to become a blacksmith in rural Wales. Instead, he contributed to astronomy, map making, navigation, longitude; and, as assay master at the Royal Mint, changed our monetary system and influenced weights and measures still used globally.
October 31, 2025 at 10:30 AM Everybody can reply
1 likes
1
kinetoplastpapers.bsky.social
kinetoplastids papers
@kinetoplastpapers.bsky.social
Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections pubmed.ncbi.nlm.nih.gov/41165401/
October 31, 2025 at 8:37 AM Everybody can reply
pastelbio.bsky.social
PastelBio
@pastelbio.bsky.social
Sequential denaturation and protein precipitation assay (SDPP) improves the sensitivity for ligand target identification at the proteome level www.sciencedirect.co...

---
#proteomics #prot-paper
October 31, 2025 at 8:00 AM Everybody can reply
helixbrief.bsky.social
The Helix Brief
@helixbrief.bsky.social
Using terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay and tissue morphology analysis, the researchers found that all tissues exhibited a time-dependent increase in apoptotic rate, indicating a clear correlation between postmortem interval and apoptosis progress...
October 31, 2025 at 6:02 AM Everybody can reply
1
philipcball.bsky.social
Philip Ball
@philipcball.bsky.social
They use a clever assay to figure out what these low-affinity sites are doing. Basically they also flank the high-affinity sites and act as a kind of filter to determine which TF(s) actually get to stick to those high-affinity sites (where in principle more than one TF can bind). /5
October 30, 2025 at 11:15 PM Everybody can reply
6 likes
2 6
violentwind.bsky.social
Seth MacFarplane
@violentwind.bsky.social
lithium levels the bridge operator and her deck engineer wife heparin assay
October 30, 2025 at 10:46 PM Everybody can reply
apannuti.bsky.social
Antonio Pannuti
@apannuti.bsky.social
Pritzker for President!! I am convinced he is the only one that could smash the GOP. Before someone asks me to write down an assay in order to justify this conclusion, no, it’s more of a “je ne sais quoi”. So, just gut feelings? Well, considering how voters chose options nowadays, I may be right.
October 30, 2025 at 10:03 PM Everybody can reply
3 likes
1 3
takomexplore.bsky.social
Takom Exploration
@takomexplore.bsky.social
Ore Odyssey October 29:
Assay results and a tax credit ruling for projects in BC and the YT.

takomexploration.com/so/3ePesFNq8...

#BritishColumbia #Yukon #MineralExploration #Mining #News #NewsReleases
Ore Odyssey
Real news.
takomexploration.com
October 30, 2025 at 8:46 PM Everybody can reply
castltrastondrs.bsky.social
TRAstonDrs
@castltrastondrs.bsky.social
#Medsky🧪 #IDsky #immunosky #pedsky #publichealth After nearly a decade of MeVA assay use at the National Microbiology Laboratory (NML), this has been the 1st documented instance of a false-negative result due to sequence variation.
@eurosurveillance.org
www.eurosurveillance.org/content/10.2...
Measles vaccine virus mutation following vaccination in a healthy child resulting in a false negative vaccine specific PCR test: Ontario, Canada, 2025
We report a case of a mild, self-limited rash illness in a child 18 days after measles-mumps-rubella-varicella vaccination. Initial testing with a PCR-based method failed to detect vaccine virus. Sequencing later identified a novel mutation in the probe-binding site of the vaccine assay that had arisen after vaccination and resulted in the false-negative PCR test results.
www.eurosurveillance.org
October 30, 2025 at 7:25 PM Everybody can reply
2 reposts 4 likes 1 saves
1 2 4
scibud.bsky.social
scibud.bsky.social
@scibud.bsky.social
New episode alert! We delve into a study using the Cell Painting Assay to analyze 196 small molecules impacting colorectal cancer cells. The findings reveal unexpected relationships among compounds, enhancing drug discovery. Tune in! https://tinyurl.com/SciBud-AI
October 30, 2025 at 7:01 PM Everybody can reply
pride-ebi.bsky.social
PRIDE Database
@pride-ebi.bsky.social
PXD065783 🚨

Ubiquitin C-terminal Extension DUB cleavage assay

🚨 New dataset alert! 🚨
October 30, 2025 at 7:00 PM Everybody can reply
platestealer.bsky.social
Plate Stealer
@platestealer.bsky.social
From Playboy Jan 90
SERIOUS GUITARIST that he is, Joe Satriani has shown robust streaks of humor and rebellion in his jazzy rock. Heck, anyone who played lead guitar on Mick Jagger's solo tour can't be too sedate. Satriani paused while cutting his new LP, "Flying in a Blue Dream," to assay the latest from Jeff Beck, a Satriani hero. "Jeff Beck's Guitar Shop is a 'power trio' record but definitely of the Nineties. It has almost a dance-sonic quality, yet the tracks all seem blues influenced. My favorite track, Where Were You, is the most beautiful guitar playing I've heard in years. Beck's sounds come right from the heart, unblocked by intellect. That's what has made him a great guitarist all these years-this optimum mix of his technique, his unique personality and the song itself. And Beck's decisions about when to play a note, chord or riff and when not to play have intense consequences on every track here. You get nearly his whole amazing vocabulary of sounds. I don't mean to be lightweight-but this LP is sonic candy."
October 30, 2025 at 5:51 PM Everybody can reply
1 likes
1 1
epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
Epigenome Technologies have recently expanded their single cell epigenetics assays

Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform

Learn more at lnkd.in/g3YqPrWY

#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
October 30, 2025 at 4:55 PM Everybody can reply
1 quotes 1 likes
1
gtmolecular.bsky.social
GT Molecular, Inc.
@gtmolecular.bsky.social
🌊 GT Molecular is exhibiting next week at the Great Lakes Beach Association Annual Meeting, Nov 3-5. Learn more about our rapid assay kits and testing services for source tracking, pathogen monitoring, and coastal resilience - helping communities make faster, data-driven water-safety decisions.
October 30, 2025 at 4:51 PM Everybody can reply
2 likes
1 2