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@natbiotech.nature.com

Selective RNA sequestration in biomolecular condensates directs cell fate transitions - @distefanolab.bsky.social @brumbaugh-lab.bsky.social go.nature.com/3X215du

Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology

Stem cell differentiation is controlled by manipulating RNA condensates.

go.nature.com

October 28, 2025 at 6:50 PM Everybody can reply

11 reposts 1 quotes 40 likes 8 saves

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Emily Pigott

@emilypigott.bsky.social

Very happy to share our new paper in PNAS, revealing a new late Neanderthal discovered through biomolecular techniques, revealing long-distance connections across Eurasia 🦴
@konstantinache.bsky.social @tommyhigham.bsky.social

doi.org/10.1073/pnas...

A new late Neanderthal from Crimea reveals long-distance connections across Eurasia | PNAS

The Crimean Peninsula contains several important Middle and Upper Paleolithic sites, including Starosele, Kabazi II, and Siuren I. The region has b...

doi.org

October 29, 2025 at 8:43 AM Everybody can reply

3 reposts 11 likes

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Seqera

@seqera.io

A fantastic turnout to the @nextflow.io for Bioimaging Workshop at the Society of Biomolecular Imaging and Informatics 12th Annual Conference! 🔬

Huge thanks to Ashley Dederich (Nextflow Ambassador from the University of Utah) for co-leading this workshop with us!

October 28, 2025 at 3:29 PM Everybody can reply

1 reposts 3 likes

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Emily R. Trunnell, Ph.D.

@ertrunnell.bsky.social

Speaking of organoids' ability to help us understand our uniquely human brains, the Braingeneers at @ucscgenomics.bsky.social are using them to "probe the emergence of human cognitive capacity – a property that defines what makes us human."

#neuroskyence 🧪

Screenshot from the October 20, 2025 University of California Santa Cruz linked article, “Effort aims to uncover the learning and reasoning potential of brain organoids,” by Emily Cerf. On the right, a photo taken by Carolyn Lagattuta of Assistant Professor of Biomolecular Engineering Tal Sharf, standing in a laboratory and holding a specialized chip for recording electrical activity in brain organoids.

October 28, 2025 at 12:12 PM Everybody can reply

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Alex Heath

@alexeheath.com

Sources: Sam Altman has tapped Mikhail Shapiro, an award-winning biomolecular engineer, to join his Neuralink rival Merge Labs

The hire suggests that, unlike Neuralink, Merge will take a noninvasive BCI approach that relies on gene therapy + ultrasound sources.news/p/altman-tap...

Altman taps leading researcher for BCI startup Merge Labs

The hire suggests that Merge is taking a much less invasive approach than Elon Musk’s Neuralink. Also: Sources IRL and reactions to yesterday's Snap scoop.

sources.news

October 25, 2025 at 12:07 AM Everybody can reply

4 reposts 2 quotes 7 likes 1 saves

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✨🌟 ⭐️ LoveKat ⭐️🌟✨🟦♿️🧬🏳️‍🌈🇺🇸🇺🇦🇨🇦🇲🇽🌎☮️🕊️🟪

@lovekat41.bsky.social

If this doesn't say Eugenics, I don't know what does...

chair in Cell Biology at the Skirball Institute of Biomolecular Medicine (part of the New York University School of Medicine).

October 24, 2025 at 4:30 PM Everybody can reply

1 reposts 7 likes

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ERC-StG MATRIX

@matrixerc.bsky.social

Meet the team behind the ERC Matrix Project!

We introduce Carli Peters, researcher and biomolecular archaeologist at icarehb.bsky.social
Carli studies ancient human–animal interactions using palaeoproteomics and ZooMS to extract and identify ancient proteins from bone fragments.

October 17, 2025 at 1:07 PM Everybody can reply

2 reposts 7 likes

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Rebecca Tyson

@tyguson.bsky.social

Thank you for sharing this, it’s really interesting.
Although from a later period, you may find this article useful due to the North Sea/monastic context. Lévêque et al., ‘Hiding in plain sight: the biomolecular identification of pinniped use in medieval manuscripts’ (2025). 🦭

October 17, 2025 at 7:50 PM Everybody can reply

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UW–Madison

@uwmadison.bsky.social

Andrea A. Putnam, a UW School of Medicine and Public Health assistant professor of biomolecular chemistry, has been named a 2025 Packard Foundation Fellow in Science and Engineering. Congratulations, Dr. Putnam!

Andrea Putnam awarded 2025 Packard Fellowship - School of Medicine and Public Health

www.med.wisc.edu

October 16, 2025 at 7:12 PM Everybody can reply

7 reposts 1 quotes 19 likes

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Anna Duncan

@drannaduncan.bsky.social

Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation'

Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025

Link for registration: aias.au.dk/events/show/...

October 15, 2025 at 2:41 PM Everybody can reply

6 reposts 2 quotes 9 likes

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Diego del Alamo

@delalamo.xyz

New job! Senior scientist in AI/ML at Takeda. The plan is to do some fun stuff with biomolecular foundation models

October 13, 2025 at 8:59 PM Everybody can reply

1 reposts 18 likes

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tompeskett.bsky.social

@tompeskett.bsky.social

Peter Rüegg wrote a great summary of our recent paper about how yeast cells use biomolecular condensates to make decisions. Thank you, Peter!

ETH Zurich @ethz.ch · 27d

All cells – from mammalian cells to microbes – can follow different biological paths. Whether they grow and divide, specialise, age or die depends on the pathway they take. New findings by researchers at ETH Zurich could help influence a cell’s decisions to target diseases such as cancer.

Protein condensates determine a cell’s fate

Do cells contain a mechanism that decides on their fates? Researchers at ETH Zurich have demonstrated in a new study that large clusters of molecules determine a cell’s future.

ethz.ch

October 11, 2025 at 7:32 AM Everybody can reply

2 likes

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Physics of Life Dresden

@poldresden.bsky.social

Attention colleagues! Interested in an interdisciplinary #PhD? 🧬 Apply now for one of 12 PhD positions exploring biomolecular #condensates! This program involves several PoL PIs, bridging the gap between physics and biology.

Apply here: dresdencondensates.org/join-us/
🗓Deadline: 24. October

October 9, 2025 at 2:32 PM Everybody can reply

4 reposts 7 likes

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Alexandrova Lab

@alexandrovalab.bsky.social

We conducted a #ChemNobel prediction poll in the group on the #NobelPrize in Chemistry Eve!

(PS: we might be a little biased 😉) #chemsky #compchem #compchemsky

Bar chart titled “Chemistry Nobel Prize 2025 Prediction Poll.”
The chart lists predicted discoveries and scientists, sorted by increasing number of votes.

Biomolecular Condensates — Brangwynne, Hyman, Rosen (1 vote)

Chemical Biology — Chi-Huey Wong, Stuart Schreiber, Peter Schultz (1 vote)

Reticular Chemistry — Omar Yaghi, Makoto Fujita, Richard Robson (2 votes)

Controlled Radical Polymerization — Ezio Rizzardo, Krzysztof Matyjaszewski, Mitsuo Sawamoto (2 votes)

C–N Coupling — Stephen Buchwald, John Hartwig (2 votes)

DNA Synthesis — Marvin Carruthers (2 votes)

Electron Transfer — Harry Gray, Jacqueline Barton (2 votes)

Next-gen DNA Sequencing — David Klenerman, Shankar Balasubramanian, Jonas Mayer (3 votes)

Single-Atom Catalysts — Tao Zhang et al. (4 votes)

Ab initio Molecular Dynamics — Roberto Car, Michele Parrinello (6 votes)

Ab initio MD received the highest number of votes in the poll.

October 8, 2025 at 3:14 AM Everybody can reply

2 reposts 16 likes

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Hannes Stark

@hannes-stark.bsky.social

Tomorrow we have a reading group session with @nscorley and @SimMat20 about "Accelerating Biomolecular Modeling with AtomWorks and RF3" www.biorxiv.org/content/10.1...

We will also discuss how to close the gap between AF3 and its open source replications!

portal.valencelabs.com/starklyspeak...

October 5, 2025 at 8:21 PM Everybody can reply

8 likes

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bioRxiv Biophysics

@biorxiv-biophys.bsky.social

A Dynamical Density Functional Theory Framework for Non-Equilibrium Phase Dynamics in Biomolecular Condensates https://www.biorxiv.org/content/10.1101/2025.10.02.680159v1

October 5, 2025 at 4:48 AM Everybody can reply

1 reposts 2 likes 2 saves

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David De Sancho

@daviddesancho.bsky.social

Check out our latest, where we investigate the molecular origin of differences between Lys and Arg and their roles in biomolecular #condensates

@dipcehu.bsky.social

www.biorxiv.org/content/10.1...

October 3, 2025 at 5:21 AM Everybody can reply

8 reposts 15 likes 2 saves

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Kresten Lindorff-Larsen

@lindorfflarsen.bsky.social

Integrative modelling of biomolecular dynamics

Time-dependent and -resolved experiments combined with computation provide a view on molecular dynamics beyond that available from static, ensemble-averaged experiments

Review w @dariagusew.bsky.social & Carl G Henning Hansen
doi.org/10.48550/arX...

$Figure 1 from the review. Caption: Comparison of a schematic example showing static, time-dependent, and time-resolved experiments illustrated by a protein folding process. (a) A static experiment measuring the observable O$_{\text{exp}}$ is shown, which can be modelled as a distribution of simulated values, O$_{\text{calc}}$, representing a conformational ensemble of folded and unfolded states. (b) Shows a time-dependent experiment, where the equilibrium dynamics of reversible folding gives rise to measured transition times $\tau_1$ and $\tau_2$. These can be modelled as equilibrium dynamics, illustrated by a free energy (FE) surface along a chosen degree of freedom (D.O.F.) (c) A time-resolved experiment probes a non-equilibrium process, where the system begins at $t_{0}$ in the folded state. During the observation time $t$ the protein unfolds until $t_{\text{max}}$. At each time point, a distinct ensemble average, O$_{\text{exp}}$, can be observed, reflecting the proteins changing structure. This evolution can be modelled as distributions of O$_{\text{calc}}$ at each time point. These are shown together with a FE surface.$

October 2, 2025 at 7:54 AM Everybody can reply

11 reposts 36 likes 6 saves

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livecomsjournal.bsky.social

@livecomsjournal.bsky.social

Interested in biomolecular simulation?

The latest article by Lier et al describes advanced tutorials for the GROMOS software, including free energy calculations, enhanced sampling and neural network potentials with SchNetPack! #compchem

livecomsjournal.org/index.php/li...

September 30, 2025 at 5:06 PM Everybody can reply

2 reposts 1 quotes 7 likes

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John Hawks

@johnhawks.net

Bringing the Harbin skull into the Denisovan fold has activated some interesting morphological comparisions. But most are forgetting a big bias: None of the tooth, jaw, or skull fossils tied so far to the Denisovans with biomolecular data seem to be female.

www.johnhawks.net/p/the-proble...

The problem when all the fossils are male

Protein data shows that most known Denisovan teeth come from male individuals, hamstringing attempts to understand the variation of this group.

www.johnhawks.net

September 29, 2025 at 2:05 PM Everybody can reply

4 reposts 2 quotes 23 likes 2 saves

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Science Magazine

@science.org

Continuous protein monitoring is an emerging area in clinical monitoring strategies.

A new #ScienceReview looks at how this approach has transformative potential for preventive health care. https://scim.ag/4nnXlyB

Schematics of clinical integration of continuous biomolecular monitoring across the spectrum of preventative health care and challenges to integration and data handling in care settings.

September 29, 2025 at 7:18 PM Everybody can reply

4 reposts 28 likes 3 saves

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Magnetic Resonance News

@nmr900.bsky.social

UK’s most powerful NMR Facility to open at the University of Birmingham @unibirmingham.bsky.social The University has received a 1.2 Gigahertz NMR spectrometer, one of only two in the UK, to enable groundbreaking research in biomolecular mechanisms www.birmingham.ac.uk/news/2025/uk... #NMRchat 🧲

UK’s most powerful NMR Facility to open at the University of Birmingham
The University has received a 1.2 Gigahertz NMR spectrometer, one of only two in the UK, to enable groundbreaking research in biomolecular mechanisms.

September 22, 2025 at 7:04 PM Everybody can reply

1 reposts 8 likes

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American Association of Wine Economists AAWE

@wineecon.bsky.social

Dr Patrick McGovern, a leading biomolecular archaeologist in the field of ancient alcoholic beverages, has died aged 80. IMcGovern provided strong scientific evidence that winemaking in Georgia dates back to the Early Neolithic (~8,000 years ago).
www.decanter.com/wine-news/in...

‘Indiana Jones of ancient wine’ Patrick McGovern dies - Decanter

Patrick McGovern, a leading biomolecular archaeologist in the field of ancient alcoholic beverages, has passed away aged 80.

www.decanter.com

September 22, 2025 at 1:26 AM Everybody can reply

4 reposts 18 likes

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Leah Shaffer

@leahshaffer.bsky.social

RNA based therapeutics are incredibly safe. It's literally just a short set of biomolecular instructions that degrade into nothing within a very short window of time.

Ed Belongia MD @belongia.bsky.social · Sep 20

"No vaccine was tested more extensively than the RNA vaccines, and no vaccine was given to more people than the mRNA vaccines, & they were found to be incredibly safe...and effective. They saved 20 million lives, & they stopped a pandemic that was shutting down the world."
-Drew Weissman

Matthew Herper @matthewherper.bsky.social · Sep 20

Winner of mRNA Nobel Prize says ACIP member’s claim that Covid vaccines persist is “absolutely impossible”

In Q&A, Drew Weissman says vast literature shows Covid shots are safe, refutes claims from Retsef Levi
www.statnews.com/2025/09/20/d...

September 20, 2025 at 5:03 PM Everybody can reply

1 reposts 9 likes

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BABAO 2025 Annual Conference

@babao2025meeting.bsky.social

#BABAO2025 Poster Sessions:

3 — ‘Biomolecular analyses in bioarchaeology’ 💀⚗️🧬

September 20, 2025 at 9:20 AM Everybody can reply

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