🚀 Check out the newly improved Harnos Lab webpages!

Our research on cell polarity, development, and migration - now with a fresh look.

👉 ueb1.sci.muni.cz/ofiz/en/harn...

#CellPolarity #DevelopmentalBiology #Xenopus #WntSignaling

#PDE4DIP activation plays a critical role in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway, thereby offering potential targets and therapeutic strategies. #medsky

#OpenAccess:

This study identifies #PDE4DIP as a key player in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway. #LVNC

Two cells, one twist 🧬🔁
Myosin asymmetry breaks mirror symmetry & sparks spontaneous 3D rotations in doublets.
Adherens junctions🩶, focal adhesions🟢 & actomyosin🔴 Biology meets active matter physics.
#CellPolarity #Fluorescencefriday #ActiveMatter #Microscopy

🧪 Canonical autophagy isn’t enough! In our new study, only CASM can coordinate the membrane remodeling needed to build a single lumen in tubes. Read how CASM drives endocytic recycling to drive morphogenesis www.biorxiv.org/content/10.1...
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity

Mechanistic insights into how PDE4DIP contributes to the #pathogenesis of left ventricular non-compaction (#LVNC) by regulating #CellPolarity, cytoskeleton architecture, & energy metabolism through the Rho-ROCK pathway. #cardiomyopathy #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Mechanistic insights into how PDE4DIP contributes to the #pathogenesis of left ventricular non-compaction (#LVNC) by regulating #CellPolarity, cytoskeleton architecture, & energy metabolism through the Rho-ROCK pathway. #cardiomyopathy #medsky

#OpenAccess: www.sciencedirect.co...

Introducing #ambassadorISRRWP6 B. Jazmin Reyes H. @bjazminrh.bsky.social
metabolism-dependent Arabidopsis roots dev. and dynamics of microtubules in lateral roots #cellpolarity #SOSEKI proteins #PlantGenetics #Molecular and #CellularBiology #Microscopy Currently in Persson’s lab Uni of Copenhagen

today at noon! #CellPolarity, #CellMigration, #DGZ, #CellBiology

Please join us for the next #DGZ #FocusWorkshop, this time on #CellPolarity and #CellMigration, Jan. 28, noon (CET) via zoom, organized by Virginie Lecaudey and Markus Engstler, featuring talks by James Cleland, Maja Matis, Anton Aebischer & Scott C. Dawson!

Defectos en la organización de la polaridad celular planar pueden participar en la patogénesis del síndrome de uña amarilla congénito y esporádico #yellownailsyndrome #cellpolarity www.acpjournals.org/doi/10.7326/...

Delighted to move over to Bluesky. We are a #CellPolarity
lab using #3Dculture to study how cells collectively move in cancer @cruk-si.bsky.social. Give us a follow if you're into 3D culture, phosphoinositides or metastasis. Strong supporter of equality and helping pull folks up the ladder.