And now: Morten Meldal - for me, THE highlight of the conference! 🧪 Host, organizer, and pioneer of click chemistry, he’s now taking the stage for an inspirational talk. A true icon shaping the future of chemical biology! #ClickChemistry @isbuc.bsky.social #CSSB25
June 13, 2025 at 2:56 PM
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🧪 New in #RSCChemicalBiology: Breakthrough in phage display! By combining unnatural amino acids with CuAAC click chemistry, this study expands molecular diversity for next-gen ligand discovery.
doi.org/10.1039/D5CB...
#PhageDisplay #ChemicalBiology #ClickChemistry
doi.org/10.1039/D5CB...
#PhageDisplay #ChemicalBiology #ClickChemistry
September 9, 2025 at 12:41 PM
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Notre doctorante Morgane Baudoin présentait ses travaux en ”click chemestry” @EuChemS_Congres
#ClickChemistry
#ClickChemistry
February 14, 2025 at 10:25 AM
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Now it’s my turn! Excited to share our latest on GCE & click chemistry for live-cell and super-resolution microscopy 🧬🔬 From precise labeling to functional imaging — come by, join in, and let’s talk science! #CSSB25 #ClickChemistry #Bioimaging
@uniregensburg.bsky.social @uni-wuerzburg.de
@uniregensburg.bsky.social @uni-wuerzburg.de
June 12, 2025 at 1:31 PM
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More outstanding work from the @santoshvardhana.bsky.social lab, second preprint dropped this week! Take time to read the bluetorial, including brilliant application of #clickchemistry 👏
#Preprint alert! Pioneering work by Tanmana Mitra, a graduate student in @wcm-imp.bsky.social, sheds new insights into why T cells become metabolically exhausted during persistent antigen encounter: www.biorxiv.org/content/10.1...
MEK-dependent bioenergetic demand drives terminal CD8+ T cell exhaustion
Loss of mitochondrial function contributes to CD8+ T cell dysfunction during persistent antigen encounter. How chronic antigen leads to this metabolic dysfunction remains unclear. Here, we show that T...
www.biorxiv.org
May 15, 2025 at 3:28 AM
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2. Using SuFEx #clickchemistry, Chao developed a ligand with exclusive specificity towards Siglec-7/-9 and converted it into a degrader that targets both Siglecs simultaneously to the lysosome for degradation.
November 25, 2024 at 7:45 PM
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Delighted to host @howarthsci.bsky.social @phar.cam.ac.uk as our first speaker of 2025 for our #biomedicalscience seminar series
Prof Mark Howarth presented his research on Protein Superglues to control cells and protect from outbreak threats #clickchemistry #celltherapy #vaccines
Prof Mark Howarth presented his research on Protein Superglues to control cells and protect from outbreak threats #clickchemistry #celltherapy #vaccines
January 17, 2025 at 1:11 PM
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What's the future of metal-free #clickchemistry? 🤔 Discover the power of #SuFEx! Explore the latest advancements and learn about the potential of sulfur(VI)-fluoride exchange reactions in our review by Renzo Luisi's group.
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
January 27, 2025 at 4:54 PM
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👥 The International Advisory Board of #IOCBPrague is gaining another world-class scientific star— #biochem Prof. M.G. Finn.
His career is closely linked with a contribution to the development of the “#clickchemistry”.
See more ► uochb.cz/en/news/722⤵️
His career is closely linked with a contribution to the development of the “#clickchemistry”.
See more ► uochb.cz/en/news/722⤵️
July 24, 2025 at 11:25 AM
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A new review on #ClickChemistry applications in plants from Ming-Ming Chen and Peng Wang et al. in Trends in Plant Science.
"Applications and opportunities of click chemistry in plant science"
www.sciencedirect.com/science/arti...
#PlantBiology #PlantScience #PlantMicroscopy
"Applications and opportunities of click chemistry in plant science"
www.sciencedirect.com/science/arti...
#PlantBiology #PlantScience #PlantMicroscopy
Applications and opportunities of click chemistry in plant science
The Nobel Prize in Chemistry for 2022 was awarded to the pioneers of Lego-like ‘click chemistry’: combinatorial chemistry with remarkable modularity a…
www.sciencedirect.com
August 29, 2023 at 7:29 AM
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Just published: “inCu-click: DNA-enhanced ligand enables live-cell click chemistry with copper catalyst” in @natcomms.nature.com! 🚀
A DNA-conjugated chelator locks Cu⁺ ions for in situ CuAAC at nanomolar doses—zero toxicity.
Read the full paper here ➡️ rdcu.be/enfHz #clickchemistry
A DNA-conjugated chelator locks Cu⁺ ions for in situ CuAAC at nanomolar doses—zero toxicity.
Read the full paper here ➡️ rdcu.be/enfHz #clickchemistry
inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst
Nature Communications - Tracking biomolecules in living cells requires fast but gentle labeling. Here, authors introduce inCu-click, a DNA-conjugated ligand that localizes copper to enable...
rdcu.be
May 29, 2025 at 1:08 PM
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#TechnologyTuesday 🚀 𝗔dvanced Tracer Compounds — Multicolor, streptavidin-free cell labeling with bio-orthogonal click chemistry for detailed, interference-free imaging.
#ClickChemistry #Electrophysiology #Neuroscience #Fluorescence #TechnologyTuesday
BioVaria 2025 👉 bsky.app/profile/biovaria
#ClickChemistry #Electrophysiology #Neuroscience #Fluorescence #TechnologyTuesday
BioVaria 2025 👉 bsky.app/profile/biovaria
Technology Tuesday
New Technology Available
oaidalleapiprodscus.blob.core.windows.net
May 7, 2025 at 12:10 PM
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📢 Our latest work describing a new versatile click chemistry glycan linker which enabled us to create glycan derivatives for use in microarrays, Luminex (bead based arrays) and ELISA assays.
Check it out in @acs.org ACS Central Science doi.org/10.1021/acsc...
#glycotime #clickchemistry #luminex
Check it out in @acs.org ACS Central Science doi.org/10.1021/acsc...
#glycotime #clickchemistry #luminex
Novel Click Coupling Chemistry to Explore Glycan Recognition
Specific recognition of glycans by proteins is important in many biological processes and immune responses. Here we present a general approach for derivatizing free glycans with a novel linker MTZ (3-...
doi.org
April 24, 2025 at 5:52 PM
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🤠 WANTED: Azide- or Alkyne-Linked Molecules!
😬 Guilty of being incredibly attractive to the Click Chemistry beads available from Bangs Labs!
🏆 Claim your reward today: visit our website at www.bangslabs.com
#clickchemistry #molecules #beads #microspheres #bangslabs
😬 Guilty of being incredibly attractive to the Click Chemistry beads available from Bangs Labs!
🏆 Claim your reward today: visit our website at www.bangslabs.com
#clickchemistry #molecules #beads #microspheres #bangslabs
May 22, 2025 at 4:56 PM
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CFATA UNAM 📑 | #Clickchemistry | #followscience
El artículo de portada del Dr. Gonzalo Ramírez-García y colaboradores: muestra una vista de nubes sobre las montañas de El Puerto de Santa Rosa en Guanajuato (México), que se elevan hasta 2700 m sobre el nivel del mar. 👨🔬
El artículo de portada del Dr. Gonzalo Ramírez-García y colaboradores: muestra una vista de nubes sobre las montañas de El Puerto de Santa Rosa en Guanajuato (México), que se elevan hasta 2700 m sobre el nivel del mar. 👨🔬
March 21, 2025 at 7:07 PM
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Tertrazines are ideal for pre-targeted imaging, drug delivery, and bioorthogonal chemistry. browse our range of click chemistry reagents and much much more on our site!
#Chemistry #ClickChemistry #Imaging #MolecularBiology #MedChem
fluorochem.co.uk/product-cate...
🧪
#Chemistry #ClickChemistry #Imaging #MolecularBiology #MedChem
fluorochem.co.uk/product-cate...
🧪
September 23, 2025 at 10:46 AM
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🆕New in #JEV🆕 Small extracellular vesicles engineered using click chemistry to express chimeric antigen receptors show enhanced efficacy in acute liver failure #extracellularvesicles #liverfailure #clickchemistry isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
February 6, 2025 at 2:14 PM
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This is a fantastic use of Bioorthogonal chemistry and #clickchemistry to assemble multi-specific engagers to recruit different types of immune cells for #cancerimmunotherapy www.cell.com/cell/fulltex...
Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
A triple orthogonal linker (T-Linker)-based programmable platform enables integration
of therapeutic modules into multimodal targeting chimeras (Multi-TACs) for tumor-targeted
co-engagement of differe...
www.cell.com
November 30, 2024 at 3:24 PM
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@jenabioscience.bsky.social has the most comprehensive catalogue of #nucleotides & #nucleosides for applications in #drugdiscovery #clickchemistry probe labeling ..
Choose your label sugar phosphate label position & more parameters
🔗https://www.stratech.co.uk/jena_bioscience/nucleotides-nucleosides/
Choose your label sugar phosphate label position & more parameters
🔗https://www.stratech.co.uk/jena_bioscience/nucleotides-nucleosides/
October 15, 2025 at 7:02 AM
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#research #bioorthogonal #clickchemistry
Sulfonated Hydroxyaryl-Tetrazines with Increased pKa for Accelerated Bioorthogonal Click-to-Release Reactions in Cells (Vrábel) -
Angewandte Chemie International Edition: doi.org/10.1002/anie...
@iocbprague.bsky.social #CzechAcademyofSciences #tu_wien
Sulfonated Hydroxyaryl-Tetrazines with Increased pKa for Accelerated Bioorthogonal Click-to-Release Reactions in Cells (Vrábel) -
Angewandte Chemie International Edition: doi.org/10.1002/anie...
@iocbprague.bsky.social #CzechAcademyofSciences #tu_wien
Sulfonated Hydroxyaryl‐Tetrazines with Increased pKa for Accelerated Bioorthogonal Click‐to‐Release Reactions in Cells
Bioorthogonal reactions that enable switching molecular functions by breaking chemical bonds have gained prominence, with the tetrazine-mediated cleavage of trans-cyclooctene caged compounds (click-t....
doi.org
September 24, 2024 at 9:03 AM
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#TechnologyTuesday 🚀 𝗔dvanced Tracer Compounds — Multicolor, artifact-free cell labeling powered by click chemistry for high-res imaging and electrophysiology.
#ClickChemistry #Electrophysiology #Fluorophores #TechnologyTuesday #BiotinAnalogue
BioVaria 2025 👉 bsky.app/profile/biovaria
#ClickChemistry #Electrophysiology #Fluorophores #TechnologyTuesday #BiotinAnalogue
BioVaria 2025 👉 bsky.app/profile/biovaria
Technology Tuesday
New Technology Available
oaidalleapiprodscus.blob.core.windows.net
May 7, 2025 at 11:54 AM
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🚀 Click chemistry meets cancer research!
Triazole-based #cycloadditions provide an efficient pathway to novel #anticancer agents. Check out this must-read, part of SynOpen’s 20 Most-Cited Articles 2023/2024!
🔗 www.thieme-connect.com/products/ejo...
#ClickChemistry #DrugDiscovery #chemotherapy
Triazole-based #cycloadditions provide an efficient pathway to novel #anticancer agents. Check out this must-read, part of SynOpen’s 20 Most-Cited Articles 2023/2024!
🔗 www.thieme-connect.com/products/ejo...
#ClickChemistry #DrugDiscovery #chemotherapy
April 28, 2025 at 9:51 AM
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#ClickChemistry meets living cells: 🔬 Andrea Rentmeister at LMU Munich makes the invisible visible: her research on mRNA therapies & epitranscriptomics combines chemistry & biology - for the medicine of tomorrow. 🔐 #LMUMunich #chemistry #research Find out more: www.lmu.de/en/newsroom/...
February 5, 2025 at 10:53 AM
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Thrilled to start my Professorship in `Bioimaging` at @uniregensburg.bsky.social ! Looking forward to exciting science, new ideas, and great collaborations! 🏛️🎓🔬
(Still 1% suspicious it might be an elaborate April Fools’ Joke🤔)
#Bioimaging #ChemicalBiology #ClickChemistry #April1
(Still 1% suspicious it might be an elaborate April Fools’ Joke🤔)
#Bioimaging #ChemicalBiology #ClickChemistry #April1
April 1, 2025 at 1:27 PM
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🔬 Discover how #ClickChemistry is revolutionizing #glycoscience!
In this review, Sagar & team explore the synthesis of 1,2,3-triazole-linked glycohybrids with promising bioactivities.
💡 A top 20 most cited article of 2023/2024!
🔗 Read here: www.thieme-connect.com/products/ejo...
In this review, Sagar & team explore the synthesis of 1,2,3-triazole-linked glycohybrids with promising bioactivities.
💡 A top 20 most cited article of 2023/2024!
🔗 Read here: www.thieme-connect.com/products/ejo...
May 20, 2025 at 10:02 AM
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