man being audhd and doing full-time work is so hard. exec dysfunction from adhd is diminished some by meds but the autistic exec dysfunction is still there! along w the sensory issues! and hyperfixations! like i can work but i can’t function well outside of that so
November 12, 2025 at 8:08 PM
man being audhd and doing full-time work is so hard. exec dysfunction from adhd is diminished some by meds but the autistic exec dysfunction is still there! along w the sensory issues! and hyperfixations! like i can work but i can’t function well outside of that so
Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes https://www.biorxiv.org/content/10.1101/2025.11.10.687674v1
November 12, 2025 at 8:05 PM
Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes https://www.biorxiv.org/content/10.1101/2025.11.10.687674v1
Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes https://www.biorxiv.org/content/10.1101/2025.11.10.687674v1
November 12, 2025 at 8:05 PM
Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes https://www.biorxiv.org/content/10.1101/2025.11.10.687674v1
Really interested in the why? DNA? famiia dysfunction? Societal norms? Really asking for a friend
November 12, 2025 at 7:41 PM
Really interested in the why? DNA? famiia dysfunction? Societal norms? Really asking for a friend
through which immunoglobulins from ME/CFS patients can cause this mitochondrial dysfunction in cells.
#ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
www.medrxiv.org/content/10.1...
#ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
www.medrxiv.org/content/10.1...
ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
Autoimmunity is a key clinical feature in both post-infectious Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulin...
www.medrxiv.org
November 12, 2025 at 7:35 PM
through which immunoglobulins from ME/CFS patients can cause this mitochondrial dysfunction in cells.
#ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
www.medrxiv.org/content/10.1...
#ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
www.medrxiv.org/content/10.1...
Prof. Bhupesh Prusty’s previous research (funded by ME Research UK with the financial support of the Gordon Parish Charitable Trust) found that immunoglobulins taken from people with ME/CFS caused dysfunction of the mitochondria when mixed with cells taken from healthy individuals (these results are
Understanding the mechanism and role of autoimmunity in ME/CFS
Listen to this article Researcher Prof. Bhupesh Prusty Institution Riga Stradins University, Riga, Latvia Start date August 2025 Funding ME Research UK Background Our immune system is responsible for ...
www.meresearch.org.uk
November 12, 2025 at 7:35 PM
Prof. Bhupesh Prusty’s previous research (funded by ME Research UK with the financial support of the Gordon Parish Charitable Trust) found that immunoglobulins taken from people with ME/CFS caused dysfunction of the mitochondria when mixed with cells taken from healthy individuals (these results are
beautiful day beautiful vibes executive dysfunction be DAMNED!!!!
November 12, 2025 at 7:32 PM
beautiful day beautiful vibes executive dysfunction be DAMNED!!!!
1. Meds should be taken for ca 9 months (a typical recommendation)
2. actual frequency of sexual dysfunction, which is high for SSRI and SNRI
3. Withdrawal problems
I expect this would impact the SWD.
And BTW: patients are usually not informed about this, unfortunately
2. actual frequency of sexual dysfunction, which is high for SSRI and SNRI
3. Withdrawal problems
I expect this would impact the SWD.
And BTW: patients are usually not informed about this, unfortunately
November 12, 2025 at 7:24 PM
1. Meds should be taken for ca 9 months (a typical recommendation)
2. actual frequency of sexual dysfunction, which is high for SSRI and SNRI
3. Withdrawal problems
I expect this would impact the SWD.
And BTW: patients are usually not informed about this, unfortunately
2. actual frequency of sexual dysfunction, which is high for SSRI and SNRI
3. Withdrawal problems
I expect this would impact the SWD.
And BTW: patients are usually not informed about this, unfortunately
SARS covid can cause "synaptic dysfunction", the mechanism detailed here.
So tl;dr: the brain fog is real and the mechanism known. Repeated exposure is probably not a good idea for your cognitive function
So tl;dr: the brain fog is real and the mechanism known. Repeated exposure is probably not a good idea for your cognitive function
🧠 Daily Feed of Brain Damage 🧠
Metformin in vitro has been demonstrated to protect against Dopa senescence... More good evidence to imply value in acute infection 🙏🏻
doi.org/10.1371/jour...
Metformin in vitro has been demonstrated to protect against Dopa senescence... More good evidence to imply value in acute infection 🙏🏻
doi.org/10.1371/jour...
SARS-CoV-2 spike protein causes synaptic dysfunction and p-tau and α-synuclein aggregation leading cognitive impairment: The protective role of metformin
Patients recovering from post-coronavirus disease 2019 (COVID-19) often experience cognitive dysfunction, including difficulties with focusing, conversation, or memory issues, which can persist for we...
doi.org
November 12, 2025 at 7:22 PM
SARS covid can cause "synaptic dysfunction", the mechanism detailed here.
So tl;dr: the brain fog is real and the mechanism known. Repeated exposure is probably not a good idea for your cognitive function
So tl;dr: the brain fog is real and the mechanism known. Repeated exposure is probably not a good idea for your cognitive function
Zionism could be his next stop, but it won't be sincere. Again, he's a compulsive contrarian with substance abuse issues, executive dysfunction and 10,000 enablers. I wouldn't be surprised if he swore allegiance, basked in the disapproval, then showed up to one of their functions dressed as Hitler.
November 12, 2025 at 7:21 PM
Zionism could be his next stop, but it won't be sincere. Again, he's a compulsive contrarian with substance abuse issues, executive dysfunction and 10,000 enablers. I wouldn't be surprised if he swore allegiance, basked in the disapproval, then showed up to one of their functions dressed as Hitler.
i love how sees hurts each other in their grief. i really love it. this kind of inter-party tension and dysfunction is something i feel is missing in later persona games. even metaphor doesn't really hit these notes the way i wish i did
November 12, 2025 at 7:21 PM
i love how sees hurts each other in their grief. i really love it. this kind of inter-party tension and dysfunction is something i feel is missing in later persona games. even metaphor doesn't really hit these notes the way i wish i did
Why would you bring more ppl into the dysfunction!? Lmao
@spoileddiva86.bsky.social
@spoileddiva86.bsky.social
November 12, 2025 at 7:15 PM
Why would you bring more ppl into the dysfunction!? Lmao
@spoileddiva86.bsky.social
@spoileddiva86.bsky.social
I don’t think the media should frame government dysfunction as a matter of which political party is “winning.”
November 12, 2025 at 7:06 PM
I don’t think the media should frame government dysfunction as a matter of which political party is “winning.”
Agree, but beyond ‘only’ the character issue, something more inalterable: [arguably may be a] personality disorder, one or more: narcissistic PD, or sociopathy, or psychopathy - so there may be both a ‘chosen’ moral dimension to the dysfunction but also a deeper, even more frightening pathology.
November 12, 2025 at 7:02 PM
Agree, but beyond ‘only’ the character issue, something more inalterable: [arguably may be a] personality disorder, one or more: narcissistic PD, or sociopathy, or psychopathy - so there may be both a ‘chosen’ moral dimension to the dysfunction but also a deeper, even more frightening pathology.
Executive dysfunction is a hell of a thing. How can it be real?! But it is, and it's not lessened by economic circumstances. I also have patreon and ko-fi and other options.
• www.patreon.com/nicklas
• ko-fi.com/nyvinter
• nyvinter.carrd.co
• www.patreon.com/nicklas
• ko-fi.com/nyvinter
• nyvinter.carrd.co
Get more from Nicklas Andersson on Patreon
creating illustrations, comics, and some RPG thingamabobs
www.patreon.com
November 12, 2025 at 6:53 PM
Executive dysfunction is a hell of a thing. How can it be real?! But it is, and it's not lessened by economic circumstances. I also have patreon and ko-fi and other options.
• www.patreon.com/nicklas
• ko-fi.com/nyvinter
• nyvinter.carrd.co
• www.patreon.com/nicklas
• ko-fi.com/nyvinter
• nyvinter.carrd.co
They have no idea how it works in the rest of the industrialized world. Republicans and the politicians who receive big bucks from healthcare sectors that profit from the dysfunction block meaningful reform.
November 12, 2025 at 6:52 PM
They have no idea how it works in the rest of the industrialized world. Republicans and the politicians who receive big bucks from healthcare sectors that profit from the dysfunction block meaningful reform.
Does anyone else suffer from Executive Diaper Dysfunction? I know I need to take a bath get my day going, but I don't need a change yet, and the diaper is honestly a higher priority.
November 12, 2025 at 6:37 PM
Does anyone else suffer from Executive Diaper Dysfunction? I know I need to take a bath get my day going, but I don't need a change yet, and the diaper is honestly a higher priority.
I think I may need new medication. For years now, I've felt what I can only describe as "executive dysfunction paralysis" where I will think & dream about what I WANT to do but never do it, stay in one place not moving for a long time, and sleeping a lot. I tried to ignore it but it's def a problem
November 12, 2025 at 6:36 PM
I think I may need new medication. For years now, I've felt what I can only describe as "executive dysfunction paralysis" where I will think & dream about what I WANT to do but never do it, stay in one place not moving for a long time, and sleeping a lot. I tried to ignore it but it's def a problem
The book "Daddy Issues & More Books" takes all this dysfunction and turns it into comedy.
Not because it's funny.
Because laughter might be the only rational response left when the world's biggest joke is on all of us.
Not because it's funny.
Because laughter might be the only rational response left when the world's biggest joke is on all of us.
November 12, 2025 at 6:23 PM
The book "Daddy Issues & More Books" takes all this dysfunction and turns it into comedy.
Not because it's funny.
Because laughter might be the only rational response left when the world's biggest joke is on all of us.
Not because it's funny.
Because laughter might be the only rational response left when the world's biggest joke is on all of us.
This degree of cognitive dysfunction is difficult to acquire at his age and is usually a preexisting condition
My assumption is JD Vance was always this stupid, but when he was just "that guy from Ohio," most of us did not have him on our radar.
My assumption is JD Vance was always this stupid, but when he was just "that guy from Ohio," most of us did not have him on our radar.
November 12, 2025 at 6:17 PM
This degree of cognitive dysfunction is difficult to acquire at his age and is usually a preexisting condition
My assumption is JD Vance was always this stupid, but when he was just "that guy from Ohio," most of us did not have him on our radar.
My assumption is JD Vance was always this stupid, but when he was just "that guy from Ohio," most of us did not have him on our radar.
Yup. The Executive Dysfunction is hitting hard today. ☕️
November 12, 2025 at 6:12 PM
Yup. The Executive Dysfunction is hitting hard today. ☕️
YOU CAN GET RID OF ONE FOR THE SAKE OF YOUR BUSINESS:
1. Executive Dysfunction
2. Rejection Sensitivity
3. Time Blindness
4. Sensory Overload
5. Lack of Object Permanence
1. Executive Dysfunction
2. Rejection Sensitivity
3. Time Blindness
4. Sensory Overload
5. Lack of Object Permanence
November 12, 2025 at 6:03 PM
YOU CAN GET RID OF ONE FOR THE SAKE OF YOUR BUSINESS:
1. Executive Dysfunction
2. Rejection Sensitivity
3. Time Blindness
4. Sensory Overload
5. Lack of Object Permanence
1. Executive Dysfunction
2. Rejection Sensitivity
3. Time Blindness
4. Sensory Overload
5. Lack of Object Permanence
Poor Alastor, he's been suffering from ear-rectile dysfunction all season! 😂😂
(Seriously, I am hilarious.)
#hazbinhotelseason2 #hazbinhotelspoilers
(Seriously, I am hilarious.)
#hazbinhotelseason2 #hazbinhotelspoilers
November 12, 2025 at 5:55 PM
Poor Alastor, he's been suffering from ear-rectile dysfunction all season! 😂😂
(Seriously, I am hilarious.)
#hazbinhotelseason2 #hazbinhotelspoilers
(Seriously, I am hilarious.)
#hazbinhotelseason2 #hazbinhotelspoilers