#enzymetherapy
Our latest paper is out!
We explored MalA, a hyperthermostable GH31 α-glucosidase, as a model to study Pompe disease mutations & chaperone therapy.

Check it out: www.tandfonline.com/doi/full/10....

#PompeDisease #Biochemistry #Glycosidases #EnzymeTherapy #Extremozymes #CAZymes
A stable GH31 α-glucosidase as a model system for the study of mutations leading to human glycogen storage disease type II
GH31 glycosidases are widespread across organisms, but remarkably, less than 1% of them have been biochemically characterised to date. Among them, human lysosomal acid α-glucosidase (GAA) stands ou...
www.tandfonline.com
March 5, 2025 at 1:27 PM