RNA-binding FBF proteins control germline stem cell differentiation. Here, the authors show that three long non-coding RNAs bind, condense, and thus inhibit FBFs to promote the transition of germline stem cells into meiosis.

Autism spectrum disorder (ASD) is a class of complex neurodevelopment disorders with high genetic he

Cardiac desmosomes are specialized cell junctions responsible for cardiomyocytes mechanical coupling. Mutation in desmosomal genes cause autosomal dominant and recessive familial arrhythmogenic cardio...

Overview The National Cancer Institute (NCI) has launched a new virtual seminar series titled NCI Rising Scholars: Cancer Research Seminar Series. This monthly seminar series is an opportunity to h...

In a groundbreaking study that has captured the attention of the scientific community, researchers have unveiled important insights into the role of long non-coding RNA (lncRNA) MALAT1 in the context of diabetic lower limb atherosclerotic disease. This research brings to light a previously overlooked aspect of diabetic complications, emphasizing the intricate interplay of molecular factors that exacerbate these conditions. The findings suggest that targeting MALAT1 could open up new therapeutic avenues for managing diabetic atherosclerosis, a significant concern for millions of individuals suffering from diabetes-related health issues worldwide.

Objective Hepatocellular carcinoma (HCC) presents substantial genetic and phenotypic diversity, making it challenging to predict patient outcomes. There is a clear need for novel biomarkers to better…