#neuroSkyence
Adopting an engineering mindset will help the field focus its research priorities, writes @timothyoleary.bsky.social.

#neuroskyence

www.thetransmitter.org/systems-neur...
Neuroscience needs engineers—for more reasons than you think
Adopting an engineering mindset will help the field focus its research priorities.
www.thetransmitter.org
November 10, 2025 at 6:56 PM
𝗜𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗮 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝗻𝗲𝘁𝘄𝗼𝗿𝗸?
In a sense yes, but does network science help us understand the brain as a complex system? Intriguing paper.
If anything the paper has 800+ refs!
#neuroskyence #complexsystems
doi.org/10.1016/j.pl...
November 10, 2025 at 6:14 PM
Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.

#neuroskyence

bit.ly/47MXYLH
Without monkeys, neuroscience has no future
Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.
bit.ly
November 10, 2025 at 2:56 PM
Hidden Markov Models
Speaking of HMMs, really enjoyed this paper on dynamics underlying resting state and other conditions. The idea of a baseline state from which excursions lead to more integrated states is really interesting.
doi.org/10.7554/eLif...
#neuroskyence
November 9, 2025 at 3:03 PM
Now that we have Hidden Markov Models do we still need correlation matrices?? 😀
For example, this looks cool.

(I'm aware that HMMs are not new, I played with them in grad school...)
doi.org/10.1016/j.is...
#neuroskyence
November 8, 2025 at 4:12 PM
A study in Nature Neuroscience shows that the moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered brain activity, pupil size and brain fluid movement. #neuroskyence 🧪
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics - Nature Neuroscience
Yang et al. show that moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered brain activity, pupil size and brain fluid movement.
go.nature.com
November 8, 2025 at 2:11 AM
AI has come an enormous way since the early days...
Amazing precision and scholarly knowledge.
GoaLPleation for one is just around the corner in neuroscience research 😱
#neuroskyence
November 11, 2025 at 3:55 PM
Great tips from @hormiga.bsky.social for your first scientific conference — in perfect time for #SfN2025!

#neuroskyence

scienceforeveryone.science/getting-the-...
Getting the most of out a scientific conference
A slightly unconventional guide to your first time
scienceforeveryone.science
November 9, 2025 at 9:38 PM
Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary.

#neuroskyence @changlabucsf.bsky.social
Human cortical dynamics of auditory word form encoding
We perceive continuous speech as a series of discrete words, despite the lack of clear acoustic boundaries. The superior temporal gyrus (STG) encodes …
www.sciencedirect.com
November 8, 2025 at 5:26 PM
One final plug before the weekend, and I promise next week onwards will be a state space free zone. Have a good weekend!

#neuroskyence #psychscisky #cognition 🧪
November 7, 2025 at 5:32 PM
Neuroscientists of the bluest sky:

I'm trying to identify seminal papers that have reshaped our understanding of brain-body connections (could be in any system).

Which papers come to mind?

#neuroskyence
November 6, 2025 at 8:30 PM
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution — a Review by Jeffrey J. Colgren & Pawel Burkhardt

@jeffcolgren.bsky.social @pawelburkhardt.bsky.social

#neuroscience #neuroskyence

www.nature.com/articles/s41...
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution - Nature Reviews Neuroscience
Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were co-opted into functional assemblies and...
www.nature.com
November 6, 2025 at 4:21 PM
This is 🤯

All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.

#neuroskyence #mri #brainmapping

A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
A probabilistic histological atlas of the human brain for MRI segmentation - Nature
NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...
share.google
November 6, 2025 at 5:35 AM
Delighted to share our new preprint!

We show that rhythmic light stimulation produces multiplexed oscillatory responses at fundamental and harmonic frequencies that are spatially, temporally, and functionally distinct.

Read on for the details [1/6]

www.biorxiv.org/content/10.1...
#neuroskyence
Rhythmic light stimulation elicits multiple concurrent neural responses that separably shape human perception
Rhythmic light stimulation offers solutions to innumerable cognitive and neurological disorders. However, like any neuromodulatory technique, responses to rhythmic light stimulation are highly variabl...
www.biorxiv.org
November 7, 2025 at 11:55 AM
The neural circuits and signalling pathways of opioid use disorder — a Review by Victor P. Mathis, Aliza T. Ehrlich & Emmanuel Darcq

#neuroscience #neuroskyence

www.nature.com/articles/s41...
The neural circuits and signalling pathways of opioid use disorder - Nature Reviews Neuroscience
In many parts of the world, opioid use disorder presents a growing challenge to public health, reinforcing the need to decipher its underlying mechanisms. Mathis et al. provide an overview of our curr...
www.nature.com
November 6, 2025 at 4:26 PM
Stop by to say hello and see some great science!
#Sfn2025 #Neuroscience #neuroskyence
November 10, 2025 at 8:55 PM
Recording single neurons at scale in the primate brain — a Tools of the Trade article by Frank F. Lanfranchi

#neuroscience #neuroskyence

www.nature.com/articles/s41...
Recording single neurons at scale in the primate brain - Nature Reviews Neuroscience
In this Tools of the Trade article, Frank F. Lanfranchi describes Neuropixels 1.0 NHP, which allows the tracking of co-ordinated activity of hundreds of neurons across different brain areas in non-hum...
www.nature.com
November 7, 2025 at 9:59 AM
A set of 12 papers published in Nature journals offers new atlases of brain development and hints at the varied evolutionary origins of different cell types.

By Holly Barker

#neuroskyence

www.thetransmitter.org/spectrum/con...
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
www.thetransmitter.org
November 5, 2025 at 6:26 PM
Protective microglia subtype offers potential therapeutic pathway in Alzheimer's disease www.mountsinai.org/about/newsro... by @mountsinainyc.bsky.social

#Alzheimers #dementia #science #neuroscience #NeuroSkyence
November 6, 2025 at 9:41 PM