What is thrombin time? #test #thrombin
What is thrombin time? #test #thrombin
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October 20, 2025 at 5:35 AM
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As per a previous post, ultrasound can be used to release thrombin from aptamers. The same effect can be achieved by pH-change. This catch-and-release system termed pHAST is further described here:
dx.doi.org/10.1021/acs....
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pHAST (pH-Driven Aptamer Switch for Thrombin) Catch-and-Release of Target Protein
A pH-driven DNA nanomachine based on the human α-thrombin binding aptamer was designed for the specific catch-and-release of human α-thrombin at neutral and acidic pH, respectively. In neutral conditi...
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October 17, 2025 at 11:36 AM
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Chimera, a hybrid molecule combining salivary peptides from a leech, tsetse fly and rat flea binds to the blood clotting enzyme thrombin with extraordinary strength.
Ultrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms
Hybrid molecule featuring leech, tsetse fly and flea peptide fragments binds thrombin at three sites
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October 16, 2025 at 11:00 AM
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The researchers found that a single oxo-εA modification at specific positions can increase the aptamer's affinity for thrombin by tenfold. Furthermore, a double oxo-εA modification resulted in Ag+-dependent aptamer activity, mimicking the crucial T:T base pair.
October 15, 2025 at 12:39 PM
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This study explores the use of a fluorescent nucleotide analog, 7,8-dihydro-8-oxo-1,N6-ethenoadenine (oxo-εA), to investigate the conformational changes and folding kinetics of the thrombin-binding aptamer.
October 15, 2025 at 12:39 PM
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Unlock the secrets of G-quadruplex assembly with a fluorescent nucleotide! This breakthrough introduces cation-regulated activity into the thrombin-binding aptamer, paving the way for adv...
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Full analysis: https://helixbrief.com/article/bc0e2ed6-0391-494e-8555-b7dcca574e1e
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Full analysis: https://helixbrief.com/article/bc0e2ed6-0391-494e-8555-b7dcca574e1e
October 15, 2025 at 12:39 PM
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worsening the clinical picture through shared mechanisms that damage 🫀 tissue & impair function.
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October 13, 2025 at 11:51 AM
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Ultrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms #Science #HealthandMedicine #InfectiousDiseases #ThrombinInhibitor #Biochemistry #HealthResearch
Ultrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms
Hybrid molecule featuring leech, tsetse fly and flea peptide fragments binds thrombin at three sites
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October 11, 2025 at 11:00 AM
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Ultrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms | Research
https://www.newsbeep.com/il/65864/
Salivary peptide fragments from a leech, a tsetse fly and a rat flea have been combined to create…
https://www.newsbeep.com/il/65864/
Salivary peptide fragments from a leech, a tsetse fly and a rat flea have been combined to create…
Ultrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms | Research - Israel News Beep
Salivary peptide fragments from a leech, a tsetse fly and a rat flea have been combined to create a synthetic protein that clamps onto thrombin, the key
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October 10, 2025 at 1:40 PM
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🩸 Thrombin-JMI & Thrombocoll Market Report 2025: Industry Dynamics, Growth Forecast & Key Trends
Read More @ goodprnews.com/thrombin-jmi...
#marketresearchreport #marketresearch #marketintelligence #marketreport #industryanalysis #TheBusinessResearchCompany #TBRC #ThrombinJMI&Thrombocoll
Read More @ goodprnews.com/thrombin-jmi...
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Thrombin-Jmi, Thrombocoll Market Analysis 2025-2034: Growth Insights, Trends, and Market Dynamics - Good PR News
How much is the thrombin-jmi, thrombocoll market worth, and how is it expected to expand? The thrombin-jmi, thrombocoll market size has XX (HCAGR) in recent years. It will grow from $XX million in 202...
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October 10, 2025 at 10:09 AM
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Crystalline Energy Funneling in Mixed-Ligand Zr-MOFs Drives Radical-Triggered ECL Amplification for Ultrasensitive Thrombin Sensing http://dx.doi.org/10.1021/acssensors.5c02948
October 9, 2025 at 3:31 PM
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Dabigatran prevents lipopolysaccharide mediated apoptosis in zebrafish through a thrombin independent mechanism https://www.biorxiv.org/content/10.1101/2025.10.03.680206v1
October 5, 2025 at 12:01 PM
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Dabigatran prevents lipopolysaccharide mediated apoptosis in zebrafish through a thrombin independent mechanism https://www.biorxiv.org/content/10.1101/2025.10.03.680206v1
October 5, 2025 at 12:01 PM
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Facet-Controlled Synthesis of Nanoporous Metal–Organic Frameworks for Enhanced Activity of Surface-Immobilized Thrombin http://dx.doi.org/10.1021/acsanm.5c04107
September 29, 2025 at 1:18 PM
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Thrombin Market Size, Growth, Trends Reports 2034 | MRFR www.marketresearchfuture.com/reports/thro...
Thrombin Market Size, Growth, Trends Reports 2034 | MRFR
Thrombin Market growth is projected to reach USD 5.87 Billion, at a 4.72% CAGR by driving industry size, share, top company analysis, segments research, trends and forecast report 2025 to 2034
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September 26, 2025 at 11:30 AM
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Evolutionary and translational mismatches in snake venom thrombin-like enzyme-induced fibrin-clot formation between human and diverse animal plasmas
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing to ascertain…
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing to ascertain…
Evolutionary and translational mismatches in snake venom thrombin-like enzyme-induced fibrin-clot formation between human and diverse animal plasmas
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing to ascertain differential coagulotoxic effects between humans and animals, and therefore the suitability of animal models to predict human effects, are scarce. To fill this knowledge gap, this study tested how pitviper with thrombin-like venoms act across vertebrate plasmas and whether animal models predict human outcomes.
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September 20, 2025 at 7:02 PM
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Evolutionary and translational mismatches in snake venom thrombin-like enzyme-induced fibrin-clot formation between human and diverse animal plasmas todayheadline
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing…
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing…
Evolutionary and translational mismatches in snake venom thrombin-like enzyme-induced fibrin-clot formation between human and diverse animal plasmas todayheadline
Snake venoms produce dynamic effects upon the blood chemistry of both prey species and human bite victims. However, comparative testing to ascertain differential coagulotoxic effects between humans and animals, and therefore the suitability of animal models to predict human effects, are scarce. To fill this knowledge gap, this study tested how pitviper with thrombin-like venoms act across vertebrate plasmas and whether animal models predict human outcomes.
todayheadline.co
September 20, 2025 at 11:34 AM
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🧬This team reports a new #prothrombin mutation (Ile441Met) linked to #venousthromboembolism in a Han Chinese family. Thrombin generation assays show clear hypercoagulability in carriers.
Details here: www.rpthjournal.org/article/S247...
Details here: www.rpthjournal.org/article/S247...
September 12, 2025 at 6:04 PM
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Combined oral contraception (COC) alters hemostasis in ways standard labs may underestimate.
Thrombin generation assays with anti-PS and anti-TFPI antibodies revealed a marked reduction in anticoagulant activity after just 3 months of COC use.
www.rpthjournal.org/article/S247...
Thrombin generation assays with anti-PS and anti-TFPI antibodies revealed a marked reduction in anticoagulant activity after just 3 months of COC use.
www.rpthjournal.org/article/S247...
September 11, 2025 at 6:02 PM
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From South Africa:
The Effects of Pseudoserum on Thrombin-Induced Fibrin Networks: Potential for Clinical Insight into Coagulation Independent of Clotting Factors
www.preprints.org/manuscript/2...
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The Effects of Pseudoserum on Thrombin-Induced Fibrin Networks: Potential for Clinical Insight into Coagulation Independent of Clotting Factors
www.preprints.org/manuscript/2...
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September 11, 2025 at 1:15 AM
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September 10, 2025 at 2:55 PM
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They found that tumor cells induce thrombin formation and fibrin polymerization, which stabilizes the tumor-platelet aggregates, even without full platelet activation.
August 27, 2025 at 8:31 PM
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Easy bruisability (pancake makeup on a bruise-from smashing his fist, or needing an IV?): he's got A-fib and is on a direct thrombin inhibitor as a guess. I guess that Adderall and tachycardia finally combined to matter. #medsky
August 23, 2025 at 1:39 AM
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The paper summarizes the biology, synthesis, and activation of FVIII, emphasizing its role in thrombin generation and endothelial dysfunction. FVIII is implicated in various inflammatory and thrombotic disorders, including COVID-19, sepsis, and cancer-associated thrombosis.
August 22, 2025 at 7:08 AM
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A naturally occurring factor VIII variant with elevated clotting activity and reduced response to activated protein C may explain severe thrombosis and offers a possible new therapeutic approach for hemophilia A. Learn more: nej.md/45eDMSR
#MedSky #Hematology #CardioSky
#MedSky #Hematology #CardioSky
August 17, 2025 at 1:01 PM
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