Longitudinal Changes in Cortical Response Dynamics with Deep Brain Stimulation to the Subcallosal Cingulate for Treatment-Resistant Depression
Alagapan, S. et al.
Paper
Details
#DeepBrainStimulation #TreatmentResistantDepression #CorticalDynamics
Alagapan, S. et al.
Paper
Details
#DeepBrainStimulation #TreatmentResistantDepression #CorticalDynamics
December 15, 2025 at 9:04 AM
Longitudinal Changes in Cortical Response Dynamics with Deep Brain Stimulation to the Subcallosal Cingulate for Treatment-Resistant Depression
Alagapan, S. et al.
Paper
Details
#DeepBrainStimulation #TreatmentResistantDepression #CorticalDynamics
Alagapan, S. et al.
Paper
Details
#DeepBrainStimulation #TreatmentResistantDepression #CorticalDynamics
It's neither a moral failure nor a permanent condition.
There are DOZENS of effective next-step treatments: tDCS, TMS, ketamine/esketamine, ECT, augmentation strategies, etc. Many of them go into full remission after being labeled “treatment resistant.”👏
#TreatmentResistantDepression #MentalHealth
There are DOZENS of effective next-step treatments: tDCS, TMS, ketamine/esketamine, ECT, augmentation strategies, etc. Many of them go into full remission after being labeled “treatment resistant.”👏
#TreatmentResistantDepression #MentalHealth
November 21, 2025 at 7:37 AM
It's neither a moral failure nor a permanent condition.
There are DOZENS of effective next-step treatments: tDCS, TMS, ketamine/esketamine, ECT, augmentation strategies, etc. Many of them go into full remission after being labeled “treatment resistant.”👏
#TreatmentResistantDepression #MentalHealth
There are DOZENS of effective next-step treatments: tDCS, TMS, ketamine/esketamine, ECT, augmentation strategies, etc. Many of them go into full remission after being labeled “treatment resistant.”👏
#TreatmentResistantDepression #MentalHealth
Vor der Narkose machten die österreichische Anästhesistin und der bayrische Psychiater mir noch die linguistische Freude und diskutierten über Bedeutung und Aussprache von "Springinkerl". #EKT4TRD #TreatmentResistantDepression
November 5, 2025 at 7:34 PM
Vor der Narkose machten die österreichische Anästhesistin und der bayrische Psychiater mir noch die linguistische Freude und diskutierten über Bedeutung und Aussprache von "Springinkerl". #EKT4TRD #TreatmentResistantDepression
Hoher Besuch heute. Ein Professor aus New York, der führend in der EKT- und VNS-Forschung ist. Gemeinsam mit zwei AssistentInnen kam er um von meinen Erfahrungen mit diesen Behandlungsformen zu hören.
#EKT4TRD #VNS4TRD #TreatmentResistantDepression
#EKT4TRD #VNS4TRD #TreatmentResistantDepression
November 5, 2025 at 2:15 PM
Hoher Besuch heute. Ein Professor aus New York, der führend in der EKT- und VNS-Forschung ist. Gemeinsam mit zwei AssistentInnen kam er um von meinen Erfahrungen mit diesen Behandlungsformen zu hören.
#EKT4TRD #VNS4TRD #TreatmentResistantDepression
#EKT4TRD #VNS4TRD #TreatmentResistantDepression
Ketamine’s fast action makes it especially beneficial for treating patients who are suicidal or who have an acute depressive episode. It’s also effective for #treatmentresistantdepression and helps relieve physical #pain caused by depression. www.paloaltomindbody.com/services/dep...
Depression
Trusted Depression Specialist serving Palo Alto, CA. Contact us at 650-681-2900 or visit us at 206 California Ave, Palo Alto, CA 94306: Palo Alto Mind Body
www.paloaltomindbody.com
November 4, 2025 at 6:29 PM
Ketamine’s fast action makes it especially beneficial for treating patients who are suicidal or who have an acute depressive episode. It’s also effective for #treatmentresistantdepression and helps relieve physical #pain caused by depression. www.paloaltomindbody.com/services/dep...
Mein Bruder war da und hat das Klavier gestimmt. Und gemeint, man würde so stark merken, was sich bei mir in den letzten 1 - 1 1/2 Jahren getan hat. Selbst darin wie (schnell und auf welche Art) ich auf Nachrichten reagiere, aber vor allem persönlich... #TreatmentResistantDepression #Depression
October 31, 2025 at 5:58 PM
Mein Bruder war da und hat das Klavier gestimmt. Und gemeint, man würde so stark merken, was sich bei mir in den letzten 1 - 1 1/2 Jahren getan hat. Selbst darin wie (schnell und auf welche Art) ich auf Nachrichten reagiere, aber vor allem persönlich... #TreatmentResistantDepression #Depression
Mind blown, Japan is conducting a clinical psilocybin study for treatment resistant depression at Keio University lead by Dr. Hiroyuki Uchida. It gives me hope for Hong Kong
#psilocybin #psychedelicscience #treatmentresistantdepression
#psilocybin #psychedelicscience #treatmentresistantdepression
October 31, 2025 at 3:34 AM
Mind blown, Japan is conducting a clinical psilocybin study for treatment resistant depression at Keio University lead by Dr. Hiroyuki Uchida. It gives me hope for Hong Kong
#psilocybin #psychedelicscience #treatmentresistantdepression
#psilocybin #psychedelicscience #treatmentresistantdepression
Ketamine therapy helps those with severe depression after other treatments fail. Consult your doctor to find out if you’re a good candidate.
#KetamineTherapy #TreatmentResistantDepression
👇 Learn More:
#KetamineTherapy #TreatmentResistantDepression
👇 Learn More:
Who Is A Good Candidate For Ketamine Therapy?
Wondering who is a good candidate for ketamine therapy? Learn how it helps emotional blocks, PTSD, and depression, and when it may not be right
maplemountainrecovery.com
October 6, 2025 at 2:02 PM
Ketamine therapy helps those with severe depression after other treatments fail. Consult your doctor to find out if you’re a good candidate.
#KetamineTherapy #TreatmentResistantDepression
👇 Learn More:
#KetamineTherapy #TreatmentResistantDepression
👇 Learn More:
Difficult-to-treat depression affects up to half of people with depression.
It drives disability, costs, and service pressures.
Yet effective add-on treatments are underused.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression #MentalHealthPolicy
It drives disability, costs, and service pressures.
Yet effective add-on treatments are underused.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression #MentalHealthPolicy
October 2, 2025 at 7:02 AM
Difficult-to-treat depression affects up to half of people with depression.
It drives disability, costs, and service pressures.
Yet effective add-on treatments are underused.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression #MentalHealthPolicy
It drives disability, costs, and service pressures.
Yet effective add-on treatments are underused.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression #MentalHealthPolicy
Calling all mental health prescribers!
20–50% of patients with depression meet criteria for treatment-resistant depression.
Evidence-based options exist, but are underused.
The LQD study tested lithium vs quetiapine as augmentation.
🧵 THREAD #TreatmentResistantDepression
buff.ly/Zvza0o1
20–50% of patients with depression meet criteria for treatment-resistant depression.
Evidence-based options exist, but are underused.
The LQD study tested lithium vs quetiapine as augmentation.
🧵 THREAD #TreatmentResistantDepression
buff.ly/Zvza0o1
Lithium versus Quetiapine in Depression: the results of the LQD study
Difficult-to-treat depression (sometimes called treatment-resistant depression) affects a large proportion of people living with depression. Many patients don’t respond fully to antidepressants, and…
youtu.be
October 1, 2025 at 7:26 AM
Calling all mental health prescribers!
20–50% of patients with depression meet criteria for treatment-resistant depression.
Evidence-based options exist, but are underused.
The LQD study tested lithium vs quetiapine as augmentation.
🧵 THREAD #TreatmentResistantDepression
buff.ly/Zvza0o1
20–50% of patients with depression meet criteria for treatment-resistant depression.
Evidence-based options exist, but are underused.
The LQD study tested lithium vs quetiapine as augmentation.
🧵 THREAD #TreatmentResistantDepression
buff.ly/Zvza0o1
If you live with depression, you’ll know treatment doesn’t always work.
About half of people still have symptoms, even after more than one medication.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
buff.ly/BtJ3ydR
About half of people still have symptoms, even after more than one medication.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
buff.ly/BtJ3ydR
Lithium versus Quetiapine in Depression: the results of the LQD study
Difficult-to-treat depression (sometimes called treatment-resistant depression) affects a large proportion of people living with depression. Many patients don’t respond fully to antidepressants, and…
youtu.be
September 30, 2025 at 7:17 AM
If you live with depression, you’ll know treatment doesn’t always work.
About half of people still have symptoms, even after more than one medication.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
buff.ly/BtJ3ydR
About half of people still have symptoms, even after more than one medication.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
buff.ly/BtJ3ydR
About half of people with depression still have symptoms even after trying more than one medication.
This is called difficult-to-treat depression.
It affects daily life, relationships, and long-term recovery.
🧵 THREAD #DifficultToTreatDepression #TreatmentResistantDepression
This is called difficult-to-treat depression.
It affects daily life, relationships, and long-term recovery.
🧵 THREAD #DifficultToTreatDepression #TreatmentResistantDepression
September 29, 2025 at 9:03 AM
About half of people with depression still have symptoms even after trying more than one medication.
This is called difficult-to-treat depression.
It affects daily life, relationships, and long-term recovery.
🧵 THREAD #DifficultToTreatDepression #TreatmentResistantDepression
This is called difficult-to-treat depression.
It affects daily life, relationships, and long-term recovery.
🧵 THREAD #DifficultToTreatDepression #TreatmentResistantDepression
In related news, I wrote this (see screenshot) on 𝕏 this past January (01.02.2025), before I initiated the process of transferring all of my stuff from there over to thee ✨️Promised Land✨️ (this here app of the clear Blue Sky...🦋):
#TRD #treatmentresistantdepression #longtermdepression #depression
#TRD #treatmentresistantdepression #longtermdepression #depression
September 19, 2025 at 8:13 PM
In related news, I wrote this (see screenshot) on 𝕏 this past January (01.02.2025), before I initiated the process of transferring all of my stuff from there over to thee ✨️Promised Land✨️ (this here app of the clear Blue Sky...🦋):
#TRD #treatmentresistantdepression #longtermdepression #depression
#TRD #treatmentresistantdepression #longtermdepression #depression
The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in treatment-resistant depression.
A new study of nearly 300,000 people suggests some genetic traits may make depression harder to treat.
🧵 THREAD
#TreatmentResistantDepression #Genetics #BiologicalPsychiatry
A new study of nearly 300,000 people suggests some genetic traits may make depression harder to treat.
🧵 THREAD
#TreatmentResistantDepression #Genetics #BiologicalPsychiatry
September 17, 2025 at 6:41 AM
The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in treatment-resistant depression.
A new study of nearly 300,000 people suggests some genetic traits may make depression harder to treat.
🧵 THREAD
#TreatmentResistantDepression #Genetics #BiologicalPsychiatry
A new study of nearly 300,000 people suggests some genetic traits may make depression harder to treat.
🧵 THREAD
#TreatmentResistantDepression #Genetics #BiologicalPsychiatry
✨Congratulations to Stuti Bansal, Yael Jacob, Laurel Morris & James Murrough for receiving the 2025 Richard and Susan Friedman Research Scholar Award for their project on #TreatmentResistantDepression (TRD). Here, Drs. James Murrough & Yael Jacob discuss their work 👉 www.youtube.com/watch?v=hE7I...
2025 FBI Research Scholars -- James Murrough and Yael Jacob
YouTube video by Icahn School of Medicine
www.youtube.com
September 8, 2025 at 1:56 PM
✨Congratulations to Stuti Bansal, Yael Jacob, Laurel Morris & James Murrough for receiving the 2025 Richard and Susan Friedman Research Scholar Award for their project on #TreatmentResistantDepression (TRD). Here, Drs. James Murrough & Yael Jacob discuss their work 👉 www.youtube.com/watch?v=hE7I...
💡 New hope for difficult-to-treat depression
Many people don’t respond to first-line treatment. What else works?
This webinar shares the latest evidence on meds, psychotherapies, neuromodulation, psychedelics, diet and exercise.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
Many people don’t respond to first-line treatment. What else works?
This webinar shares the latest evidence on meds, psychotherapies, neuromodulation, psychedelics, diet and exercise.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
September 4, 2025 at 10:01 AM
💡 New hope for difficult-to-treat depression
Many people don’t respond to first-line treatment. What else works?
This webinar shares the latest evidence on meds, psychotherapies, neuromodulation, psychedelics, diet and exercise.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
Many people don’t respond to first-line treatment. What else works?
This webinar shares the latest evidence on meds, psychotherapies, neuromodulation, psychedelics, diet and exercise.
🧵 THREAD
#DifficultToTreatDepression #TreatmentResistantDepression
"... And as the study authors note, those improvements were comparable to treatment with with antidepressants—at a fraction of the cost."
#mindfulness #depression #depressiontreatment #depressionrelief #treatmentresistantdepression
www.mindbodygreen.com/articles/thi...
#mindfulness #depression #depressiontreatment #depressionrelief #treatmentresistantdepression
www.mindbodygreen.com/articles/thi...
Research Finds An Effective Free Tool For Hard-To-Treat Depression
And it's cost-effective, too.
www.mindbodygreen.com
August 25, 2025 at 2:26 PM
"... And as the study authors note, those improvements were comparable to treatment with with antidepressants—at a fraction of the cost."
#mindfulness #depression #depressiontreatment #depressionrelief #treatmentresistantdepression
www.mindbodygreen.com/articles/thi...
#mindfulness #depression #depressiontreatment #depressionrelief #treatmentresistantdepression
www.mindbodygreen.com/articles/thi...
My article describing alternative treatments for treatment resistant depression is on the @NAMIGlendale website. namiglendale.org/alternative-...
#depression #mentalhealth #mentalillness #TMS #esketamine #ECT #psychiatrist #psychologist #treatmentresistantdepression
#depression #mentalhealth #mentalillness #TMS #esketamine #ECT #psychiatrist #psychologist #treatmentresistantdepression
namiglendale.org
June 28, 2025 at 2:22 AM
My article describing alternative treatments for treatment resistant depression is on the @NAMIGlendale website. namiglendale.org/alternative-...
#depression #mentalhealth #mentalillness #TMS #esketamine #ECT #psychiatrist #psychologist #treatmentresistantdepression
#depression #mentalhealth #mentalillness #TMS #esketamine #ECT #psychiatrist #psychologist #treatmentresistantdepression
Cortical spreading depolarization (CSD) discovered as second brain event following controlled seizure induction during #ElectroconvulsiveTherapy (ECT) for #TreatmentResistantDepression doi.org/10.1038/s414... #MentalHealth #TranslationalScience
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature Communications
The underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon...
doi.org
May 29, 2025 at 4:43 PM
Cortical spreading depolarization (CSD) discovered as second brain event following controlled seizure induction during #ElectroconvulsiveTherapy (ECT) for #TreatmentResistantDepression doi.org/10.1038/s414... #MentalHealth #TranslationalScience
Mindfulness plus the standard talk therapies has better patient outcomes, and is more cost effective. #mindfulness #depression #treatmentresistantdepression #MBCT #majordepressivedisorder
news.exeter.ac.uk/faculty-of-h...
news.exeter.ac.uk/faculty-of-h...
Mindfulness course effective in people with difficult-to-treat depression
Mindfulness-based therapy can offer significant relief for individuals who are still depressed after receiving treatment, according to a new clinical trial. Researchers hope their findings, published ...
news.exeter.ac.uk
May 15, 2025 at 2:12 PM
Mindfulness plus the standard talk therapies has better patient outcomes, and is more cost effective. #mindfulness #depression #treatmentresistantdepression #MBCT #majordepressivedisorder
news.exeter.ac.uk/faculty-of-h...
news.exeter.ac.uk/faculty-of-h...
Which condition responds BEST to ECT?
youtube.com/shorts/CVAdsKzkS7I?feature=share
#ECT #PsychiatryFacts #DepressionWithPsychoticFeatures #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
youtube.com/shorts/CVAdsKzkS7I?feature=share
#ECT #PsychiatryFacts #DepressionWithPsychoticFeatures #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
🧠 What’s the one diagnosis where ECT often falls short
YouTube video by Shrinks In Sneakers
youtube.com
May 13, 2025 at 8:02 PM
youtube.com/shorts/m8dCa...
🎥 New Short just dropped!
Which condition responds BEST to ECT?🧠💡
#ECT #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
🎥 New Short just dropped!
Which condition responds BEST to ECT?🧠💡
#ECT #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
Which condition responds BEST to ECT?
YouTube video by Shrinks In Sneakers
youtube.com
May 12, 2025 at 5:30 PM
youtube.com/shorts/m8dCa...
🎥 New Short just dropped!
Which condition responds BEST to ECT?🧠💡
#ECT #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
🎥 New Short just dropped!
Which condition responds BEST to ECT?🧠💡
#ECT #Catatonia #MentalHealthEducation #ElectroconvulsiveTherapy #TreatmentResistantDepression #PsychiatryTikTok #MedicalShorts #MentalHealthAwareness #PsychMedEd
Electroceuticals are expanding psychiatry’s toolbox | Doctors are turning to new tech for patients w/ #TreatmentResistantDepression & #OCD. Weighing in👉 @mountsinainyc.bsky.social neurologist Dr. Helen Mayberg & neurosurgeon Dr. Brian Kopell @washingtonpost.com www.washingtonpost.com/health/2025/...
April 7, 2025 at 6:24 PM
Electroceuticals are expanding psychiatry’s toolbox | Doctors are turning to new tech for patients w/ #TreatmentResistantDepression & #OCD. Weighing in👉 @mountsinainyc.bsky.social neurologist Dr. Helen Mayberg & neurosurgeon Dr. Brian Kopell @washingtonpost.com www.washingtonpost.com/health/2025/...
