Reposted by: Jennifer Weuve
What role do competing events play in #dementia research?
Paloma Rojas-Saunero (UCLA Fielding School of Public Health) is next for the 2024-2025 CAUSALab Methods Series @karolinskainst.bsky.social
📆 December 10, 2024
⏰ 15.00 CEST/9.00 ET
📍 Virtual
Register now 👇
stats.sender.net/forms/e7JD1d...
Paloma Rojas-Saunero (UCLA Fielding School of Public Health) is next for the 2024-2025 CAUSALab Methods Series @karolinskainst.bsky.social
📆 December 10, 2024
⏰ 15.00 CEST/9.00 ET
📍 Virtual
Register now 👇
stats.sender.net/forms/e7JD1d...
Reposted by: Jennifer Weuve
TOMORROW's episode of #MELODEM features...
Dr. Audrey Murchland presenting:
"Intimate Partner Violence and #Dementia Risk: Challenges and Opportunities for Longitudinal Studies of Aging."
11a US ET
Not on the zoom link email list? Mosey on over to our web lounge for deets sites.bu.edu/melodem/
Dr. Audrey Murchland presenting:
"Intimate Partner Violence and #Dementia Risk: Challenges and Opportunities for Longitudinal Studies of Aging."
11a US ET
Not on the zoom link email list? Mosey on over to our web lounge for deets sites.bu.edu/melodem/
Methods for Longitudinal Studies in Dementia (MELODEM)
sites.bu.edu
Reposted by: Jennifer Weuve
People are enraged by health insurance denials because they arise when they are at their most vulnerable and least able to respond. Both physical and mental health matter to our ability to respond to the types of administrative demands that insurers rely on.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Reposted by: Jennifer Weuve
#MELODEM, your favorite place to hash out #methodologic challenges in #dementia research, kicks off 2025 w a session ft Dr. Miguel Arce & Dr. Emily Briceño-Abreu conversing abt "Cross-national harmonization of the Harmonized Cognitive Assessment Protocol (HCAP)."
Th Jan 16, 11a US ET via zoom.
Th Jan 16, 11a US ET via zoom.
Reposted by: Jennifer Weuve
**Jan 27, 2025** <-- the last day to apply for the In-Person Meeting of #MELODEM, a sumptuous convening to collaboratively scratch heads (one's own, just so we're clear) and generate solutions to #methodologic challenges in longitudinal #dementia research.
sites.bu.edu/melodem/cale...
sites.bu.edu/melodem/cale...
Reposted by: Jennifer Weuve
FWIW, I‘ve known @usha.bsky.social and have been repeatedly impressed by her scrupulous attention to truth; her courage; and her deep respect for sourcing
Usha Lee McFarling
@usha.bsky.social
· Jan 26
Are you affected by the Trump administration’s pause on health communications, science meetings, and reviews?
Have you been affected by the Trump administration’s pause on communications, science meetings, and reviews? @statnews would like to hear from you.
www.statnews.com
Reposted by: Jennifer Weuve
Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...
Are you affected by the Trump administration’s pause on health communications, science meetings, and reviews?
Have you been affected by the Trump administration’s pause on communications, science meetings, and reviews? @statnews would like to hear from you.
www.statnews.com
Reposted by: Jennifer Weuve
#MELODEM is accepting applications--by 1/27/25--to participate in this year's Annual In-Person Meeting!
The meeting features:
Jun 23-25: presentations w extensive discussion
Jun 25-27: hands-on data workshop, involving a subset of participants
See deets & apply:
docs.google.com/forms/d/e/1F...
The meeting features:
Jun 23-25: presentations w extensive discussion
Jun 25-27: hands-on data workshop, involving a subset of participants
See deets & apply:
docs.google.com/forms/d/e/1F...
Application for 2025 Annual MELODEM Meeting
We are delighted to announce that we are accepting applications to participate in MELODEM's Annual In-Person Meeting which will be held in St. James Hotel in Red Wing, MN from Monday, June 23rd to Fri...
docs.google.com
Additional gratitude to The @tejenson.bsky.social for orchestrating the session, which included the best marketing prose on an epi/EH methods seminar invite in recent memory.
What was esp helpful about Amanda's talk was getting a firmer sense of seeing how ITB plays out with exposures distributed on a continuum (an expansion on the examples many of us have seen that involve dichotomous exposures).
In the true-story example she chronicled, effects estimated using a design that induced ITB were impressively large (one might call a HR of 51 gargantuan). Upon correction, they all shrank. & though some remained large (that HR of 51 became a HR of 5.5), some previously adverse findings became null.
A big holler-y grateful shout-out to **Amanda Gassett**, Research Scientist at University of Washington, for presenting clearly and constructively on dodging immortal time bias in studies of air pollution's health effects. #EnviroBrain #CONFAB @busph.bsky.social
Patterns of earnings trajectories (age 25 thru 60) differed by sex and a bit by birth cohort.
Cognitive decline was faster among ppl w earnings trajectories that cycled and that were consistently low. Those w consistently high earnings had the slowest mean decline.
@melodem.bsky.social
Cognitive decline was faster among ppl w earnings trajectories that cycled and that were consistently low. Those w consistently high earnings had the slowest mean decline.
@melodem.bsky.social
@ccolvin94.bsky.social presents meticulously thought-thru & generated results on life course earnings trajectories & cognitive decline, by birth cohort. The #MELODEM2025 equivalent of a walk-off HR will launch us into deep thoughts, conversations, and collaborations over the coming weeks and months.
Proposed setting/Discovery cohort: WHICAP Offspring Study (many wmn had not entered menopause as of baseline)
More enlightening lightning (talks) at #MELODEM2025: Justina Avila-Rieger dares to wade thru the thicket that is reproductive status (and aging) in relation to dementia risk. Idea: exploit DNA methylation, which can reflect changes in the endocrine system and hormonal status.
@melodem.bsky.social
@melodem.bsky.social
Exposure to fluoride was assoc'd w higher achievement in education (e.g., math). Not at all assoc'd w cogn at age 60.
So ... how about cogn later on in life?
Setting: High School & Beyond
Exposure: Based on location of pt's secondary school (>1000 high schools are represented here) and the fluoridation status of water there. Sufficient for none, part, or all of childhood.
Setting: High School & Beyond
Exposure: Based on location of pt's secondary school (>1000 high schools are represented here) and the fluoridation status of water there. Sufficient for none, part, or all of childhood.
Fluoride. Great for oral health and stunning teeth. Does it exposure to it in childhood related to cogn later in life? @ #MELODEM2025, Rob Warren (U MN) points out the extraordinarily high exposures in studies of kids' IQs: not relevant to what's in our public water supply.
@melodem.bsky.social
@melodem.bsky.social
Trend 1: cardiometabolic RF prevalence has been increasing
Trend 2: dementia incidence and prevalence have been decreasing
But, in the absence of trend 1, trend 2 (the decreases in dementia inc and prev) would have been steeper.
Trend 2: dementia incidence and prevalence have been decreasing
But, in the absence of trend 1, trend 2 (the decreases in dementia inc and prev) would have been steeper.
Now up @ #MELODEM2025, @astokespop.bsky.social teases out the contribution of secular trends in midlife cardiometabolic health in relation to trends in dementia incidence and prevalence in the US.
@melodem.bsky.social
@melodem.bsky.social
Cool innovation here: this is about the cog effects of incident trauma, not the effects of prevalent (historical) trauma.
Our next lightning bolt @ #MELODEM2025 is from Katrina Kezios, presenting research on incident traumatic experiences in relation to cog change in older adults. Upshot: these exp were assoc'd w cog decline, esp among those w worse financial well-being.
@melodem.bsky.social
@melodem.bsky.social
Iris Strangmann issues the first bolt of a lightning talk in today's #MELODEM2025. Does being multilingual offer cognitive benefits in older age? She is using data from LASI-DAD to answer this q, evaluating assns within strata of urbanicity and SES.
Younger age, male (v fem), being White (not Latinx, Black), higher mid-life income, lower cog scores, more disability, and more comorbidities. (Others coming to a journal near you.)
Carrying the #MELODEM2025 baton now is Melinda Power (GW). Among ppl who have #dementia, a large % have not been diagnosed. What predicts who gets diagnosed in a timely fashion?
@melodem.bsky.social
@melodem.bsky.social
A shout-out to yesterday afternoon's and todays moderators--Suzanne Judd, @ermayeda.bsky.social, @relajoie.bsky.social, & @miguelarce.bsky.social--for shrewdly ensuring that talks run on time and discussions are inclusive.
@melodem.bsky.social
@melodem.bsky.social
A key ingredient to the appeal and success of #MELODEM2025 (as with other #MELODEM mtgs) comes from the generous blocks of time dedicated to discussion. And a key ingredient of that discussion is excellent moderating.
Broader context: A4 was viewed as innovative bc it started earlier in the course of disease. It was 5 years long. Is longer treatment duration needed? Or maybe a different agent operating via a different mechanism?