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Reposted by Luc Camoin
Reposted by Luc Camoin
Reposted by Luc Camoin
Reposted by Luc Camoin
Reposted by Luc Camoin
J.-F. Cavalier
@jefcavalier.bsky.social
· Jun 25
The polyamino‐isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi‐target inhibitors against the ESKAPEE bacterium Enterobacter cloacae
Gram-negative bacteria are particularly prone to developing antimicrobial resistance (AMR), as evidenced by the WHO's ESKAPEE list of high-priority pathogens. One strategy that has increased is the u...
onlinelibrary.wiley.com
Reposted by Luc Camoin
Reposted by Luc Camoin
Reposted by Luc Camoin
Luc Camoin
@camoinluc.bsky.social
· Jun 2
J.-F. Cavalier
@jefcavalier.bsky.social
· May 29
Mapping of Mycobacterial Enzymes Involved in Triacylglycerol Accumulation as Intrabacterial Lipid Inclusions Using Activity-Based Multitarget Inhibitor Probes
Lipids play a critical role in the physiology, life cycle, and pathogenicity of mycobacteria. They largely participate in host–pathogen interactions and fulfill important functions ranging from cell w...
pubs.acs.org
Reposted by Luc Camoin
Reposted by Luc Camoin
Reposted by Luc Camoin
Michael MacCoss
@maccoss.bsky.social
· Jun 1
Evaluation of an Orbitrap Astral Zoom mass spectrometer prototype for quantitative proteomics - beyond identification lists
Mass spectrometry instrumentation continues to evolve rapidly, yet quantifying these advances beyond conventional peptide and protein detections remains challenging. Here, we evaluate a modified Orbit...
www.biorxiv.org
Reposted by Luc Camoin
Reposted by Luc Camoin
Luc Camoin
@camoinluc.bsky.social
· May 23
Reposted by Luc Camoin
Reposted by Luc Camoin
Impens Lab
@impenslab.bsky.social
· May 16
Data-independent immunopeptidomics discovery of low-abundant bacterial epitopes
Mass spectrometry-based immunopeptidomics is a powerful approach to uncover peptides presented by human leukocyte antigen (HLA) molecules that can guide vaccine design and immunotherapies. While data-...
biorxiv.org
Reposted by Luc Camoin
Reposted by Luc Camoin
Luc Camoin
@camoinluc.bsky.social
· Apr 29
J.-F. Cavalier
@jefcavalier.bsky.social
· Apr 25
Synthesis and Anti-mycobacterial Activity of Novel Medium-chain β-Lactone Derivatives: A Multi-Target Strategy to combat Mycobacterium abscessus
The constant emergence of drug-resistant mycobacteria, together with the lack of new antibiotics entering the market, has become a global public health problem that threatens the effective treatment o...
pubs.rsc.org
Reposted by Luc Camoin
Reposted by Luc Camoin
Savitski Lab
@savitski-lab.bsky.social
· Apr 29
High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues, and bacteria
Systematic mapping of protein-ligand interactions is essential for understanding biological processes and drug mechanisms. Peptide-centric local stability assay (PELSA) is a powerful tool for detectin...
www.biorxiv.org
Luc Camoin
@camoinluc.bsky.social
· Apr 29
J.-F. Cavalier
@jefcavalier.bsky.social
· Apr 25
Synthesis and Anti-mycobacterial Activity of Novel Medium-chain β-Lactone Derivatives: A Multi-Target Strategy to combat Mycobacterium abscessus
The constant emergence of drug-resistant mycobacteria, together with the lack of new antibiotics entering the market, has become a global public health problem that threatens the effective treatment o...
pubs.rsc.org
Reposted by Luc Camoin
Reposted by Luc Camoin
