My main PhD project is out in #CancerDiscovery @theaacr.bsky.social

We found that PKC activators (TPPB) destroy tumor microtube networks that glioblastoma cells use to invade & resist therapy.

Huge thanks to my first co-author @dirkchoffmann.bsky.social , @winklerlab.bsky.social & all co-authors!

#Glioblastoma cells don’t just grow — they extend tumor microtubes that let them invade the brain 🧠 and link into multicellular networks that resist therapy ☢️.
We developed a strategy to inhibit these TMs — and make these cells vulnerable to therapy ☠️.
This study is now online @Cancer Discovery

📢New Article now published at Nature Cancer!

'Colorectal cancer cells hijack a brain–gut polysynaptic circuit from the lateral septum to enteric neurons to sustain tumor growth'

✏️By Tian-Ming Gao, Jian-Ming Li and colleagues

🔗 www.nature.com/articles/s43...

We are proud to present a Special Issue on Cancer Neuroscience, curated by editors Bennie Babayan & Ted Dobie. This issue offers a snapshot of the field through a collection of Perspectives, Reviews, and NeuroViews: cell.com/neuron/issue.... See below for details on the pieces:

Molecular recording of cellular protein kinase activity with chemical labeling:

www.nature.com/articles/s41...

Congratulations to De-en Sun and the entire team.

Need a distraction to shift your TMEntality today?
If you’re curious about how sympathetic nerve signaling rewires immune and non-immune stromal cells in the TME, dive into this review article by Ariana Sattler and the team to reimagine the TME! link.springer.com/article/10.1...

The EACR Cancer Neuroscience conference 14-16 October 2025 is open for registrations. Please bear in mind that the abstract deadline is June 30th 2025. We will be selecting a number of short talks from the abstracts! eacr.org/conference/c...

and the News & Views: www.nature.com/articles/d41...

I am happy to share our PDAC study, led by @verat-h.bsky.social.

I developed a machine-learning pipeline to analyze large 3D light sheet microscopy volumes. We uncover how pancreatic cancer rewires neurons, advancing the field of Cancer Neuroscience.

Full text here: www.nature.com/articles/s41...

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature.
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...

Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies | Cancer Discovery | American Association for Cancer Research
#paper

aacrjournals.org/cancerdiscov...

So many nice starter packs.. I couldn't find one related to spatial biology yet, so I started one 🧬🔬! Here's who I’ve included so far—let me know if you'd like to be added or suggest other must-follow accounts! #SpatialBiology

go.bsky.app/SU34ELC