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Frank @frankdejong.bsky.social · 1h

He literally demolishes the White House.

Jonathan Edwards @jonathanreports.bsky.social · 5h

Scoop: Trump has started demolishing the White House's East Wing facade to build his ballroom. The president had claimed construction of the $250 million building wouldn’t ‘interfere’ with the existing White House structure. /W @ddiamond.bsky.social wapo.st/4hqBNiU

White House begins demolishing East Wing facade to build Trump’s ballroom

The president had claimed construction of the $250 million ballroom wouldn’t ‘interfere’ with the existing White House structure.

wapo.st

Frank @frankdejong.bsky.social · 9h

Europe under attack. Now.

MAKS 25 👀🇺🇦 @maks23.bsky.social · 1d

🇬🇧⚠️ Russian hackers hit eight UK military bases and posted Ministry of Defence(MoD) staff names and emails on the dark web, - Mirror

The MoD is now investigating the massive breach that is suspected of having been carried out by the Russian group Lynx.

Frank @frankdejong.bsky.social · 9h

The army is really pissed after that hegseth meetup....

Frank @frankdejong.bsky.social · 9h

It all started during his russian period. And really I think they have those Epstein files. For a long time.

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Frank @frankdejong.bsky.social · 9h

Even long time allies disconnect from US trade and products.

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Henri Antifa @agent327.bsky.social · 13h

Wat weten advocaten er nou van? 🤔

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Peelridder @peelridder.bsky.social · 10h

En zo kan het ook..

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Frank @frankdejong.bsky.social · 11h

😂👍

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Spelling Mistakes Cost Lives @darrencullen.bsky.social · Aug 7

Did a new one

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Frank @frankdejong.bsky.social · 11h

Bij welke partij zit hij deze week?

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Bas Heijne @basheijne.bsky.social · 14h

29 oktober: stem vóór de democratie.

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Frank @frankdejong.bsky.social · 16h

You seem surprised? They are republicans.

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Frans Timmermans @franstimmermans.groenlinkspvda.nl · 16h

Trump eist schreeuwend dat Poetin van Oekraïne moet krijgen wat hij wil: controle over bijna de gehele Donbas. En anders volgt ‘vernietiging’. Compleet ontoelaatbare taal en even onaanvaardbare eisen. Wij moeten pal naast president Zelensky gaan staan.

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Chise @sailorrooscout.bsky.social · 8d

Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types.
• www.umass.edu/news/article...

The study has been published in Cell Reports Medicine. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️

HIGHLIGHTS
•Lipid NPs carrying STING and TLR4 agonists promote synergistic type I interferons
• NPs drain efficiently to lymph nodes and increase polyfunctional T and B cells
• NPs improve tumor-free outcomes with memory against multiple aggressive tumor models
SUMMARY
We report on the utility of a "super-adjuvant" nanoparticle (NP) system as a modular, customizable platform for next-generation cancer vaccination. Using nanomaterials engineering technology, we aim to harness not only the effective adjuvanticity of whole-pathogen vaccines, but also the safety of subunit vaccines.
Our lipid-based NP platform co-encapsulates agonists of the stimulator of interferon genes (STING) and Toll-like receptor 4 (TLR4) pathways to promote synergistic production of type I interferons and other
proinflammatory cytokines in innate antigen-presenting dendritic cells and macrophages.
Compared to empty NPs and free agonists, dual-adjuvant NPs administered with antigenic peptides or tumor cell lysate promote increased antigen processing and presentation, drain efficiently to nearby lymph nodes, increase polyfunctional tumor-specific T and B cells, and improve tumor-free outcomes upon vaccination and subsequent challenge with multiple aggressive tumor cells.

Graphical Abstract

The vaccine combines two immune-stimulating molecules (adjuvants) in a tiny lipid nanoparticle that enhances both innate and adaptive immune responses. The innate immune system acts as the body’s first line of defense, responding quickly and non-specifically to invaders using cells that release inflammatory signals. The adaptive immune system takes longer to activate but provides a targeted, long-lasting response, training T-cells and B- cells to recognize and remember specific threats. Together, they form a coordinated defense: the innate system alerts and activates the adaptive system, which then delivers precise and durable immunity.

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Casper Albers 🟥 @casperalbers.nl · 18h

Misschien, heel misschien, vonden we zorg al die tijd al wel gewoon superbelangrijk en hadden de journalisten dat niet goed door omdat ze als een kip zonder kop achter Geert aan holden

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Frank @frankdejong.bsky.social · 16h

These farmers didn't just vote against their interests—they voted for their own extinction, and now they're living with the consequences.
Sometimes the cruelest teacher is experience itself.

Frank @frankdejong.bsky.social · 16h

Perhaps this is democracy's harshest lesson: you can vote your way into oblivion. The question is whether the electorate learns from this cautionary tale, or whether we simply wait for economic Darwinism to run its course.

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Frank @frankdejong.bsky.social · 16h

in a perverse echo of the immigrant labor force they once employed.
And now, facing ruin, where do they turn? To the government subsidies they've long derided as socialism. To the safety net they voted to dismantle for others.

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Frank @frankdejong.bsky.social · 16h

The bitter irony deepens when we see wealthy investors—including political figures and their associates—positioning themselves to acquire foreclosed farmland at bargain prices. The very people who worked the soil for generations may soon find themselves as employees on land they once owned,

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Frank @frankdejong.bsky.social · 16h

The Harvest of Their Own Votes

These farmers were not blind to what they were choosing. The ballot boxes told the story, and they cast their votes accordingly. Now they're confronting the stark reality of a Republican agenda they helped empower.

Mark Bauer @thepurplebauer.bsky.social · 21h

Good job Trump, try some more tariffs!

Kansas, Missouri farmers went big for Trump. His tariffs are gutting them | Opinion — The Kansas City Star

China was Kansas and Missouri farmers’ biggest buyer of soybeans and milo or sorghum. Donald Trump’s tariffs destroyed that market and Brazil is stepping in.

apple.news

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Frank @frankdejong.bsky.social · 1d

Helemaal mee eens.

Frank @frankdejong.bsky.social · 1d

Dat is toch wel een terugkerende factor, de Telegraaf, al 132 jaar bruin.

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Straight w/o Hate @dellrecycles.bsky.social · 1d

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Levi @levi98k.bsky.social · 1d

En dit soort dingen normaliseren het.
bsky.app/profile/myrt...

Myrthe Hilkens @myrthehilkens.bsky.social · 1d

Zeg NOS; waarom leek het jullie een goed idee om een promotiefilm voor Forum voor Democratie te maken zonder ENIGE factcheck? Luchtiges het principe van remigratie toelichten. Echt man… anders doe er meteen een rode loper bij. Volledig van de pot gerukt.

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