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GLIORESOLVE @glioresolve.bsky.social · 17d

We are committed to tackling GBM through innovative research and collaboration. On #WorldCancerResearchDay, we celebrate the dedication of scientists and clinicians working to understand cancer, develop new therapies and improve patient outcomes. Together we push the boundaries of #cancerresearch

Reposted by GLIORESOLVE

MIMETAS @mimetas.bsky.social · Aug 27

🧠 New study from MIMETAS & Roche (pRED) shows how the ApoE4 Alzheimer’s risk gene alters brain endothelial function & iron transport.

Using our iPSC-based BBB model + Roche’s BrainShuttle tech, we uncovered ApoE4-driven changes that may shape how therapies can reach the brain. shorturl.at/RwgUP

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GLIORESOLVE @glioresolve.bsky.social · Aug 13

A new clinical trial is recruiting patients with glioblastoma — the most aggressive brain tumor in adults. KSAT’s The Conversation talks to Dr. Andrew Brenner about the study and how patients can get involved. #Glioblastoma #ClinicalTrial #BrainCancerResearch
youtu.be/5Vm95A-zVcE?...

The Conversation: Mays Cancer Center recruiting glioblastoma patients for trial

YouTube video by KSAT 12

youtu.be

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Reposted by GLIORESOLVE

GLIORESOLVE @glioresolve.bsky.social · Jul 15

📣 Join us in #Prague on 15 Oct for the GLIORESOLVE #EANO2025 satellite pre-meeting! Speakers: Prof Patrick Wen (Harvard), Prof Anna Dimberg (Uppsala), Prof Gabriele Bergers (VIB), Dr Kate Connor (TCD) plus research highlights from our PhD students. Details & registration: www.eano.eu/eano2025/pro...

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GLIORESOLVE @glioresolve.bsky.social · Aug 13

Level up your science! Explore EMBL’s hands-on courses, conferences, and learn cutting-edge techniques from world-class experts. Here is the poster for 2026 #EMBL #EMBLEvents #LifelongLearning #ScienceTraining

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GLIORESOLVE @glioresolve.bsky.social · Jul 18

Nanjing University is organizing "AI Augmented Biology," a conference in China on AI's integration with biological sciences. Topics include multi-modal data, protein engineering, and LLMs for biology.
🗓️ Oct 22-24, 2025
📍 Nanjing, China

#AIinScience #Bioinformatics #Genomics #Conference

AI Augmented Biology

Organised by Nanjing University，Nature, Nature Communications, Nature Biotechnology, Nature Methods The Nature conference on "AI Augmented Biology" explores how the integration of artificial intellige...

natureconferences.streamgo.live

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GLIORESOLVE @glioresolve.bsky.social · Jul 17

Google has introduced AlphaGenome, an AI model designed to predict the impact of genetic mutations on gene regulation across the human genome. This development aims to contribute to the understanding of disease mechanisms and potential therapeutic avenues. #AlphaGenome #AI #Genomics

AlphaGenome: AI for better understanding the genome

Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API.

deepmind.google

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GLIORESOLVE @glioresolve.bsky.social · Jul 16

Here are some links that may be of use if you or your family members are facing a glioblastoma diagnosis theibta.org
braintumourireland.com
stophersentumoren.nl
brainstrust.org.uk
www.thebraintumourcharity.org
artc-asso.fr www.thebraintumourcharity.org/living-with-...

IBTA – The International Brain Tumour Alliance (IBTA)

theibta.org

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GLIORESOLVE @glioresolve.bsky.social · Jul 16

On #GlioblastomaAwarenessDay, we reflect on lives affected by this devastating disease. In #GLIORESOLVE, we’re working to understand the complex landscape that surrounds and fuels each tumour — aiming for more personalised, effective treatments #BrainTumourResearch www.glioresolve.eu

GLIORESOLVE

www.glioresolve.eu

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Reposted by GLIORESOLVE

National Brain Tumor Society @braintumor.org · Jul 16

More than 13,000 Americans will be diagnosed with #glioblastoma in 2025, yet treatments and survival rates have remained largely unchanged for decades.

📣 This #GBMDay, reshare these stats to raise public awareness and inspire action.

Learn more: braintumor.org/events/gliob...

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GLIORESOLVE @glioresolve.bsky.social · Jul 15

We can't wait👏 We are especially looking forward to hosting an #EANO2025 satellite pre-meeting on the 15 October. Talks from Prof Patrick Wen, Prof Anna Dimberg, Prof Gabriele Bergers and Dr Kate Connor + research highlights from our students. Details & FREE registration👉 www.eano.eu/eano2025/pro...

Pre-Meetings, October 15

www.eano.eu

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GLIORESOLVE @glioresolve.bsky.social · Jul 15

📣 Join us in #Prague on 15 Oct for the GLIORESOLVE #EANO2025 satellite pre-meeting! Speakers: Prof Patrick Wen (Harvard), Prof Anna Dimberg (Uppsala), Prof Gabriele Bergers (VIB), Dr Kate Connor (TCD) plus research highlights from our PhD students. Details & registration: www.eano.eu/eano2025/pro...

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Reposted by GLIORESOLVE

Nils Blüthgen @molsysbio.bsky.social · Jun 24

Join ICSB2025 in Dublin: The late-breaking abstract deadline has been extended to August 1st (for oral presentation) and September 1st (for posters). Hope to see you in Dublin! icsb2025.com

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Reposted by GLIORESOLVE

Martine Lamfers @martinelamfers.bsky.social · Jun 10

Happy to share our latest work by Verheul, Fabro etal, describing our optimized protocol for establishing GBM cell cultures. Another step forward to personalized drugscreening for GBM patients! Thank you to everyone who contributed.🙏𝗡𝗮𝘁𝘂𝗿𝗲 𝗣𝗿𝗲𝗰𝗶𝘀𝗶𝗼𝗻 𝗢𝗻𝗰𝗼𝗹𝗼𝗴𝘆(2025)
🔗 www.nature.com/articles/s41...

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GLIORESOLVE @glioresolve.bsky.social · Jun 11

This recent study maps the transcriptional heterogeneity of IDH-wildtype glioblastoma, identifying distinct cellular states and gene programs across disease stages:
"The multilayered transcriptional architecture of glioblastoma ecosystems"
doi.org/10.1038/s415...

The multilayered transcriptional architecture of glioblastoma ecosystems - Nature Genetics

Integrated single-cell transcriptomic and genetic characterization of 121 adult glioblastomas identifies heterogeneity at cell type, cell state and baseline expression program levels associated with s...

doi.org

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GLIORESOLVE @glioresolve.bsky.social · Jun 11

It has long been known that glioblastoma(GBM) tumor microenvironment evolves; how therapy shapes the GBM TME remains poorly understood. This recent article sheds light on it: "Deciphering the longitudinal trajectories of GBM ecosystems by integrative single-cell genomics" doi.org/10.1038/s415...

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics - Nature Genetics

Comparison of paired primary and recurrent glioblastomas at the single-cell transcriptomic level describes molecular and cellular trajectories associated with tumor recurrence, highlighting extensive ...

doi.org

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GLIORESOLVE @glioresolve.bsky.social · Jun 10

📣 **SAVE THE DATE** The GLIORESOLVE consortium is hosting a satellite conference at #EANO2025 in Prague on 15 October. We have an outstanding lineup of invited speakers and exciting research updates from the network. Free registration will open soon via the EANO website. #BrainTumourResearch

Reposted by GLIORESOLVE

RCSI University of Medicine and Health Sciences @rcsi.bsky.social · May 27

Professor Annette Byrne, Professor of Physiology at RCSI and head of the RCSI Precision Cancer Medicine Group has been elected as a Member of the Royal Irish Academy, Ireland’s foremost body of experts in sciences and humanities.

🔗 tinyurl.com/4yx2auwx

#RCSIdiscover

A man and woman pose in yellow and green ceremonial robes. The woman is wearing a black silk blouse, has brown hair and a fringe and is holding a scroll and shaking the hand of the man who is wearing a navy suit and blue tie.

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GLIORESOLVE @glioresolve.bsky.social · May 27

Huge congratulations to Prof Byrne 👏🏻👏🏻

GLIORESOLVE @glioresolve.bsky.social · May 27

Congratulations again to GLIORESOLVE Coordinator Prof Annette Byrne who has been elected as a Member of the Royal Irish Academy. Read the RCSI press release here www.rcsi.com/dublin/news-... @physiologyrcsi.bsky.social @mariescurie-ire.bsky.social @horizoneu.bsky.social @researchireland.ie

Professor Annette Byrne elected as Member of the Royal Irish Academy

Professor Annette Byrne has been elected as a Member of the Royal Irish Academy (MRIA), Ireland’s foremost body of experts in the sciences and humanities. More ...

www.rcsi.com

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GLIORESOLVE @glioresolve.bsky.social · May 13

Impressive de novo enzyme design! 🧪 Researchers engineered new protein catalysts for cyclopropanation (some >99:1 e.r.!) & Si-H insertion. They even used directed evolution in whole cells to optimize! Shows efficient catalysts are designable. #ProteinDesign
www.science.org/doi/10.1126/...

De novo design of porphyrin-containing proteins as efficient and stereoselective catalysts

De novo design of protein catalysts with high efficiency and stereoselectivity provides an attractive approach toward the design of environmentally benign catalysts. Here, we design proteins that inco...

www.science.org

GLIORESOLVE @glioresolve.bsky.social · May 12

How do enhancers drive cell specificity? 🤔 Fascinating study used 64k+ synthetic sequences in blood cell differentiation & found activating TF sites often show negative synergy, converting TF gradients into sharp gene patterns! #Bioinformatics
www.cell.com/cell/fulltex...

Design principles of cell-state-specific enhancers in hematopoiesis

Screen of minimalistic enhancers in blood progenitor cells demonstrates widespread dual activator-repressor function of transcription factors (TFs) and enables the model-guided design of cell-state-sp...

www.cell.com

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GLIORESOLVE @glioresolve.bsky.social · May 12

Meet AutoBA: An autonomous AI agent simplifying complex multi-omic analysis! 🧬 Features LLM power, self-designing plans, online/local flexibility, Auto Code Repair, & adaptability to new tools. #bioinformatics #AI #genomics #LLM #AutoBA
advanced.onlinelibrary.wiley.com/doi/full/10....

An AI Agent for Fully Automated Multi‐Omic Analyses

This study introduces AutoBA, which is an AI agent designed for fully automated multi-omic analyses based large language models. AutoBA simplifies bioinformatics tasks with minimal user input, offeri...

advanced.onlinelibrary.wiley.com

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Reposted by GLIORESOLVE

Avishay Spitzer, MD, PhD @avishayspitzer.bsky.social · May 10

1/ Truly excited to share our new study that I had to privilege to co-lead during my PhD alongside great friends and collaborators @masashi-nomura.bsky.social, @kevin-johnson.bsky.social and Luciano Garofano, published at Nature Genetics @natureportfolio.nature.com!

www.nature.com/articles/s41...

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics - Nature Genetics

Comparison of paired primary and recurrent glioblastomas at the single-cell transcriptomic level describes molecular and cellular trajectories associated with tumor recurrence, highlighting extensive ...

www.nature.com

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Reposted by GLIORESOLVE

neurooncologyhd.bsky.social @neurooncologyhd.bsky.social · May 2

UNDERSTANDING AND TARGETING RESISTANCE in Glioblastoma (UNITE Glioblastoma) ist eine DFG geförderte Forschungsinitiative, Hier ein Interview mit Prof. Wolfgang Wick @wickwolfgang.bsky.social und Dr. Sophie Heuer im Rahmen der Reihe ÜBERLEBENSSTRATEGIEN: www.youtube.com/watch?v=BO3I...

SFB 1389: Überwindung der Therapieresistenz von Glioblastomen.

YouTube video by UniHeidelberg

www.youtube.com

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