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Dr. Fresh @drfresh113.bsky.social · 4h

#Rocktober2025 Day 12 -- Network

NEW PASSWORD CANNOT BE THE SAME AS YOUR OLD PASSWORD

#MegaMan #MegaManX #MegaManLegends #MegaManBattleNetwork #MegaManZero #ロックマン #ロックマンX #Rocktober

Fanart of the mega Man Battle Network series. MegaMan.EXE is standing on white tiles (like those you see in an in-game battle) looking up at a titanic Prog character looming over him. The Prog is looking down at Mega with a menacing glare, and its eyes are like those stars that some people use to convey aggressive focus. A speech bubble coming from MegaMan shows his face worried and sweating.

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Kylerocks2004☆ @kylerocks2004.bsky.social · 13h

#SonicRacingCrossWorlds Whadya think?

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mintsoya @mintsoya.bsky.social · 7h

I want to draw but stuck for ideas so here a jet doodle #jetthehawk #sonicracingcrossworlds #sonicthehedgehog

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おいやん（ごま） @oiyan-goma.bsky.social · 3h

完成102/102
本編、ひとまず無事に完成しました！🎊㊗️🎊
来年一月のイベントと通販にて頒布する予定です。
応援や励ましのお言葉を頂き、ありがとうございました！

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Breezy 💖🏳️‍⚧️ @bluebirdbreeze.bsky.social · 10h

To my fellow trans peeps and those still figuring things out, this is a great resource 💖

Trans Lifeline @translifeline.org · 19h

We can’t ignore today’s political climate and how it impacts your safety and mental health as you consider the coming out process. So, we’ve made a website to support you!

heyimtrans.com has vetted articles, guides for coming out, pre-written templates, resources for allies, and free downloads!

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pikatwig1.bsky.social @pikatwig1.bsky.social · 3h

I know. I'm just saying that, in the moment, I briefly thought it was.

Just thought this was funny and worth sharing.

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D.P (LVL UP 10/13!) 🎂✨ @dp-in-the-sky.bsky.social · 3h

As always, be sure to full-view, and shares are greatly appreciated! 🌟

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D.P (LVL UP 10/13!) 🎂✨ @dp-in-the-sky.bsky.social · 3h

You must be my lucky star‼️
Cuz you make the darkness seem so far‼️✨

#NiGHTSintoDreams
#BalanWonderworld

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Chise @sailorrooscout.bsky.social · 3h

Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types.
• www.umass.edu/news/article...

The study has been published in Cell Reports Medicine. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️

HIGHLIGHTS
•Lipid NPs carrying STING and TLR4 agonists promote synergistic type I interferons
• NPs drain efficiently to lymph nodes and increase polyfunctional T and B cells
• NPs improve tumor-free outcomes with memory against multiple aggressive tumor models
SUMMARY
We report on the utility of a "super-adjuvant" nanoparticle (NP) system as a modular, customizable platform for next-generation cancer vaccination. Using nanomaterials engineering technology, we aim to harness not only the effective adjuvanticity of whole-pathogen vaccines, but also the safety of subunit vaccines.
Our lipid-based NP platform co-encapsulates agonists of the stimulator of interferon genes (STING) and Toll-like receptor 4 (TLR4) pathways to promote synergistic production of type I interferons and other
proinflammatory cytokines in innate antigen-presenting dendritic cells and macrophages.
Compared to empty NPs and free agonists, dual-adjuvant NPs administered with antigenic peptides or tumor cell lysate promote increased antigen processing and presentation, drain efficiently to nearby lymph nodes, increase polyfunctional tumor-specific T and B cells, and improve tumor-free outcomes upon vaccination and subsequent challenge with multiple aggressive tumor cells.

Graphical Abstract

The vaccine combines two immune-stimulating molecules (adjuvants) in a tiny lipid nanoparticle that enhances both innate and adaptive immune responses. The innate immune system acts as the body’s first line of defense, responding quickly and non-specifically to invaders using cells that release inflammatory signals. The adaptive immune system takes longer to activate but provides a targeted, long-lasting response, training T-cells and B- cells to recognize and remember specific threats. Together, they form a coordinated defense: the innate system alerts and activates the adaptive system, which then delivers precise and durable immunity.

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Chise @sailorrooscout.bsky.social · 3h

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

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Serena Plush and Friends @serenaplush.bsky.social · 13h

Serena: Nice work Greninja. You really put those ninja skills to good work today.

Greninja. Gre. 🙂‍↕️

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Serena Plush and Friends @serenaplush.bsky.social · 13h

Greninja: Greninja.

Impidimp: Heh… 😥

Greninja: Ninja! *Hydro Punp*

Impidimp: Eeeee!!!! 😱

… Eeh 😵‍💫

Marnie: *sigh* Oh Impidimp….

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Serena Plush and Friends @serenaplush.bsky.social · 13h

Impidimp: Eeeeee! 😡

Marnie: Impidimp, don’t lose your cool. Stay focused.

Serena: This is our chance Greninja. Get ready to counter again.

Greninja: Gre.

Impidimp: Eeeeee! *Punch*

… Heh?

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Serena Plush and Friends @serenaplush.bsky.social · 14h

Marnie: Impidimp, he’s weak to fairy type moves too. So Play Rough!

Impidimp: Hehe!

Greninja: Ninja! *Water Shuriken*

Impidimp: Eeeeee! *Crash*

Marnie: Impidimp!

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Serena Plush and Friends @serenaplush.bsky.social · 14h

Greninja: Ninja! *Whack*

Impidimp: Eeeeeh! 😖

Marnie: He’s super fast. Even faster than Rhyhorn.

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Serena Plush and Friends @serenaplush.bsky.social · 14h

Marnie: So she’s using Greninja now. Impidimp, Greninja isn’t one to fall for easy tricks. So be careful.

Impidimp: Hehe! *Punch*

…. Heh?

Marnie: I told you to be careful. Watch out!

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Serena Plush and Friends @serenaplush.bsky.social · 14h

Serena: It’s okay Pancham. You did your best.

Impidimp is way trickier than i realized. I’ll need someone fast and skilled to defeat him.

Greninja, I choose you!

Greninja: Ninja.

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ViViVooVoo @vivivoovoo.bsky.social · 6h

Abracadabra 🪄

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Kuji (Comms Open!) @kujikawaii.bsky.social · 5h

Found the issue of persona magazine that announced p5 was gonna release just a few months after p4 dancing...lmaO

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Balilart @balileart.bsky.social · 15h

There's a Mare to Blame #MLP

card art for the card "There's a Mare to Blame" from the TSSSF expansion, True Crimes Island Times. The art is a scenic beach at sunset. Princess Celestia is prancing in the water in the background. the foreground shows a rock with a photograph on it. the photograph features Twilight Sparkle, Celestia, and Spike.

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Applegreed @ringoapplegreed.bsky.social · 20h

Cute character C0mmission
!! Team rocket Rainbow!! 🌈

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🐟DarkTidalWave🪽 @darktidalwave.bsky.social · 14h

Chemy Gijinka Wave 5

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悠哉【youzai】 @youzai.bsky.social · 14h

🌸 #digimon #デジモン

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Claire Willett @clairewillett.bsky.social · 16h

found exactly the one use of “evil recoils in the presence of Christ” I am willing to sign off on, HOOOOOOOOLY SHIT

Father Larry did not come here to fuck around

Rich Raho @richraho.bsky.social · 22h

Chicago priest Fr. Larry Dowling describes procession to ICE facility: “No one had the courage to speak directly to us. No one from Homeland Security could stand in the presence of the Monstrance holding the Blessed Sacrament. No wonder. Evil is repelled, recoils in the presence of Christ.”

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pikatwig1.bsky.social @pikatwig1.bsky.social · 14h

A~nd first time this has happened to me. It was during a double point round.

Thankfully, no damage to my fair play points. ...eh, I had to stop anyway. It went to Tap Boost, and Zetzz was about to start.

#SonicRacingCrossWorlds #NintendoSwitch

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